Zobrazeno 1 - 10
of 2 180
pro vyhledávání: '"T, Barry"'
Autor:
Nikita Sushentsev, Gregory Hamm, Lucy Flint, Daniel Birtles, Aleksandr Zakirov, Jack Richings, Stephanie Ling, Jennifer Y. Tan, Mary A. McLean, Vinay Ayyappan, Ines Horvat Menih, Cara Brodie, Jodi L. Miller, Ian G. Mills, Vincent J. Gnanapragasam, Anne Y. Warren, Simon T. Barry, Richard J. A. Goodwin, Tristan Barrett, Ferdia A. Gallagher
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-22 (2024)
Abstract Hyperpolarised magnetic resonance imaging (HP-13C-MRI) has shown promise as a clinical tool for detecting and characterising prostate cancer. Here we use a range of spatially resolved histological techniques to identify the biological mechan
Externí odkaz:
https://doaj.org/article/5d269719830146bfb19310f180c8fbe9
Autor:
Elizabeth L. Hardaker, Emilio Sanseviero, Ankur Karmokar, Devon Taylor, Marta Milo, Chrysis Michaloglou, Adina Hughes, Mimi Mai, Matthew King, Anisha Solanki, Lukasz Magiera, Ricardo Miragaia, Gozde Kar, Nathan Standifer, Michael Surace, Shaan Gill, Alison Peter, Sara Talbot, Sehmus Tohumeken, Henderson Fryer, Ali Mostafa, Kathy Mulgrew, Carolyn Lam, Scott Hoffmann, Daniel Sutton, Larissa Carnevalli, Fernando J. Calero-Nieto, Gemma N. Jones, Andrew J. Pierce, Zena Wilson, David Campbell, Lynet Nyoni, Carla P. Martins, Tamara Baker, Gilberto Serrano de Almeida, Zainab Ramlaoui, Abdel Bidar, Benjamin Phillips, Joseph Boland, Sonia Iyer, J. Carl Barrett, Arsene-Bienvenu Loembé, Serge Y. Fuchs, Umamaheswar Duvvuri, Pei-Jen Lou, Melonie A. Nance, Carlos Alberto Gomez Roca, Elaine Cadogan, Susan E. Critichlow, Steven Fawell, Mark Cobbold, Emma Dean, Viia Valge-Archer, Alan Lau, Dmitry I. Gabrilovich, Simon T. Barry
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-20 (2024)
Abstract The Ataxia telangiectasia and Rad3-related (ATR) inhibitor ceralasertib in combination with the PD-L1 antibody durvalumab demonstrated encouraging clinical benefit in melanoma and lung cancer patients who progressed on immunotherapy. Here we
Externí odkaz:
https://doaj.org/article/189773f2417346dcbdf8b6281d57effa
Autor:
Lorna Hopcroft, Eleanor M. Wigmore, Stuart C. Williamson, Susana Ros, Cath Eberlein, Jennifer I. Moss, Jelena Urosevic, Larissa S. Carnevalli, Sara Talbot, Lauren Bradshaw, Catherine Blaker, Sreeharsha Gunda, Venetia Owenson, Scott Hoffmann, Daniel Sutton, Stewart Jones, Richard J. A. Goodwin, Brandon S. Willis, Claire Rooney, Elza C. de Bruin, Simon T. Barry
Publikováno v:
npj Breast Cancer, Vol 9, Iss 1, Pp 1-14 (2023)
Abstract Combining the selective AKT inhibitor, capivasertib, and SERD, fulvestrant improved PFS in a Phase III clinical trial (CAPItello-291), treating HR+ breast cancer patients following aromatase inhibitors, with or without CDK4/6 inhibitors. How
Externí odkaz:
https://doaj.org/article/216706db2e6b4b6eae15d98244910c27
Autor:
Kim A. Hoffman, Emma Thompson, Marina Gaeta Gazzola, Lindsay M. S. Oberleitner, Anthony Eller, Lynn M. Madden, Ruthanne Marcus, David E. Oberleitner, Mark Beitel, Declan T. Barry
Publikováno v:
Addiction Science & Clinical Practice, Vol 18, Iss 1, Pp 1-12 (2023)
Abstract Background During the period of community re-entry immediately following release from jail or prison, individuals with opioid use disorder (OUD) face structural barriers to successful re-entry and high risk of overdose. Few published studies
Externí odkaz:
https://doaj.org/article/6d79b3ed3aad4c1abcd32fb313f5a0d4
Autor:
Dustin J. Flanagan, Raheleh Amirkhah, David F. Vincent, Nuray Gundaz, Pauline Gentaz, Patrizia Cammareri, Aoife J. McCooey, Amy M. B. McCorry, Natalie C. Fisher, Hayley L. Davis, Rachel A. Ridgway, Jeroen Lohuis, Joshua D. G. Leach, Rene Jackstadt, Kathryn Gilroy, Elisa Mariella, Colin Nixon, William Clark, Ann Hedley, Elke K. Markert, Douglas Strathdee, Laurent Bartholin, Keara L. Redmond, Emma M. Kerr, Daniel B. Longley, Fiona Ginty, Sanghee Cho, Helen G. Coleman, Maurice B. Loughrey, Alberto Bardelli, Timothy S. Maughan, Andrew D. Campbell, Mark Lawler, Simon J. Leedham, Simon T. Barry, Gareth J. Inman, Jacco van Rheenen, Philip D. Dunne, Owen J. Sansom
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-18 (2022)
It remains critical to identify colorectal cancers (CRC) that will disseminate as early as possible. Here, the authors identify CRC tumours that are aggressive and prone to early dissemination, characterised by epithelial TGFβ and growth-factor sign
Externí odkaz:
https://doaj.org/article/685f337608c24440b7e084866104173a
Autor:
Lynn M. Madden, Scott O. Farnum, Daniel J. Bromberg, Declan T. Barry, Alyona Mazhnaya, Tetiana Fomenko, Anna Meteliuk, Ruthanne Marcus, Julia Rozanova, Iurii Poklad, Sergii Dvoriak, Frederick L. Altice
Publikováno v:
Addiction Science & Clinical Practice, Vol 17, Iss 1, Pp 1-7 (2022)
Abstract Background Efficient and linguistically appropriate instruments are needed to assess response to addiction treatment, including severity of addiction/mental health status. This is critical for Russian-speaking persons in Eastern Europe and C
Externí odkaz:
https://doaj.org/article/2924dc6535e0418d8780464d9b0c0969
Publikováno v:
Telematics and Informatics Reports, Vol 10, Iss , Pp 100054- (2023)
The potential validity and utility of a joy of missing out (JOMO) construct in relation to social media use, self-perception, and indicators of mental health was examined. This research follows from evidence that fear of missing out (FOMO) on social
Externí odkaz:
https://doaj.org/article/51fa945203b24ff49adf97a907ead590
Autor:
William Oles, Marcus Alexander, Navin Kumar, Benjamin Howell, Patrick G. O’Connor, Lynn M. Madden, Declan T. Barry
Publikováno v:
BMC Psychiatry, Vol 22, Iss 1, Pp 1-10 (2022)
Abstract Background Despite the growing morbidity and mortality rates associated with opioid use disorder, a large gap still exists between treatment need and capacity. Low-threshold clinics utilizing medication for opioid use disorder (MOUD) treatme
Externí odkaz:
https://doaj.org/article/417d75decdf047b6bde080c859820df8
Autor:
Lorna Hopcroft, Eleanor M. Wigmore, Stuart C. Williamson, Susana Ros, Cath Eberlein, Jennifer I. Moss, Jelena Urosevic, Larissa S. Carnevalli, Sara Talbot, Lauren Bradshaw, Catherine Blaker, Sreeharsha Gunda, Venetia Owenson, Scott Hoffmann, Daniel Sutton, Stewart Jones, Richard J. A. Goodwin, Brandon S. Willis, Claire Rooney, Elza C. de Bruin, Simon T. Barry
Publikováno v:
npj Breast Cancer, Vol 9, Iss 1, Pp 1-1 (2023)
Externí odkaz:
https://doaj.org/article/597341a4bba64230b85546c506522cc0