Zobrazeno 1 - 10
of 303
pro vyhledávání: '"Szymon W"'
Autor:
Szymon W. Manka
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-3 (2023)
Cell division critically requires amplification of microtubules (MTs) in the bipolar mitotic spindle. This relies on the filamentous augmin complex that enables MT branching. Studies by Gabel et al., Zupa et al. and Travis et al. describe consistent
Externí odkaz:
https://doaj.org/article/ac7f056450d2493d823e2c20650a61b8
Autor:
Szymon W. Manka, Wenjuan Zhang, Adam Wenborn, Jemma Betts, Susan Joiner, Helen R. Saibil, John Collinge, Jonathan D. F. Wadsworth
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-11 (2022)
High-resolution structures of mammalian prions have remained elusive. Here, Manka et al. report the cryo-EM structure of infectious RML prion fibrils from mice. Structural similarity with recently reported infectious 263K prion fibrils from hamsters
Externí odkaz:
https://doaj.org/article/9b6eb942195b4bc19be04c9aa47b9d02
Autor:
Rai, Ankit, Liu, Tianyang, Katrukha, Eugene A., Estévez-Gallego, Juan, Manka, Szymon W., Paterson, Ian, Díaz, J. Fernando, Kapitein, Lukas C., Moores, Carolyn A., Akhmanova, Anna
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America, 2021 Dec . 118(51), 1-11.
Externí odkaz:
https://www.jstor.org/stable/27117543
Autor:
Bhamra, Savroop, Arora, Parineeta, Manka, Szymon W., Schmidt, Christian, Brown, Craig, Rayner, Melissa L.D., Klöhn, Peter-Christian, Clarke, Anthony R., Collinge, John, Jat, Parmjit S.
Publikováno v:
In Journal of Molecular Biology 28 February 2023 435(4)
Autor:
Szymon W. Kmiecik, Qiaoni Shi, Ye-Guang Chen, Jannis Moormann, Tatjana M. Hildebrandt, Amy Schade, Martin Fischer, Kyusik Q. Kim
Publikováno v:
Trends in Biochemical Sciences. 48:491-494
Autor:
Szymon W. Manka, Adam Wenborn, Jemma Betts, Susan Joiner, Helen R. Saibil, John Collinge, Jonathan D.F. Wadsworth
Publikováno v:
Nature Chemical Biology. 19:607-613
Recent cryogenic electron microscopy (cryo-EM) studies of infectious, ex vivo, prion fibrils from hamster 263K and mouse RML prion strains revealed a similar, parallel in-register intermolecular β-sheet (PIRIBS) amyloid architecture. Rungs of the fi
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Publikováno v:
Cell and Tissue Research. 392:167-178
Mammalian prions are lethal transmissible pathogens that cause fatal neurodegenerative diseases in humans and animals. They consist of fibrils of misfolded, host-encoded prion protein (PrP) which propagate through templated protein polymerisation. Pr
Akademický článek
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Publikováno v:
Advances in Sciences and Technology, Vol 18, Iss 4, Pp 250-264 (2024)
This paper presents the results of comparative studies of strain modulus from static (PLT) and dynamic (LWD) plate testing. The tests were conducted on 9 sections of forest roads with different surfaces made of unbound aggregates. They produced 140-e
Externí odkaz:
https://doaj.org/article/31c13dc1f34b4c0b84af95497c21252b