Zobrazeno 1 - 10
of 44
pro vyhledávání: '"Szymon M Kiełbasa"'
Autor:
Kazimierz Oksza-Orzechowski, Edwin Quinten, Shadi Shafighi, Szymon M. Kiełbasa, Hugo W. van Kessel, Ruben A. L. de Groen, Joost S. P. Vermaat, Julieta H. Sepúlveda Yáñez, Marcelo A. Navarrete, Hendrik Veelken, Cornelis A. M. van Bergen, Ewa Szczurek
Publikováno v:
Genome Biology, Vol 25, Iss 1, Pp 1-31 (2024)
Abstract Tumours exhibit high genotypic and transcriptional heterogeneity. Both affect cancer progression and treatment, but have been predominantly studied separately in follicular lymphoma. To comprehensively investigate the evolution and genotype-
Externí odkaz:
https://doaj.org/article/e8dea72bd5804a5db13255b3e28f964b
Autor:
Rayna J. S. Anijs, El Houari Laghmani, Betül Ünlü, Szymon M. Kiełbasa, Hailiang Mei, Suzanne C. Cannegieter, Frederikus A. Klok, Peter J. K. Kuppen, Henri H. Versteeg, Jeroen T. Buijs
Publikováno v:
Research and Practice in Thrombosis and Haemostasis, Vol 6, Iss 5, Pp n/a-n/a (2022)
Abstract Background Colorectal cancer patients have an increased risk of developing venous thromboembolism (VTE), resulting in increased morbidity and mortality. Because the exact mechanism is yet unknown, risk prediction is still challenging; theref
Externí odkaz:
https://doaj.org/article/2c0b1feb2ee14dffae9ea1e831e36f88
Autor:
Shadi Darvish Shafighi, Szymon M. Kiełbasa, Julieta Sepúlveda-Yáñez, Ramin Monajemi, Davy Cats, Hailiang Mei, Roberta Menafra, Susan Kloet, Hendrik Veelken, Cornelis A.M. van Bergen, Ewa Szczurek
Publikováno v:
Genome Medicine, Vol 13, Iss 1, Pp 1-16 (2021)
Abstract Background Drawing genotype-to-phenotype maps in tumors is of paramount importance for understanding tumor heterogeneity. Assignment of single cells to their tumor clones of origin can be approached by matching the genotypes of the clones to
Externí odkaz:
https://doaj.org/article/3d2fdb3a359f473fa50be1499b8e526d
Autor:
Maria Tió-Coma, Szymon M. Kiełbasa, Susan J.F. van den Eeden, Hailiang Mei, Johan Chandra Roy, Jacco Wallinga, Marufa Khatun, Sontosh Soren, Abu Sufian Chowdhury, Khorshed Alam, Anouk van Hooij, Jan Hendrik Richardus, Annemieke Geluk
Publikováno v:
EBioMedicine, Vol 68, Iss , Pp 103379- (2021)
Background: Leprosy, a chronic infectious disease caused by Mycobacterium leprae, is often late- or misdiagnosed leading to irreversible disabilities. Blood transcriptomic biomarkers that prospectively predict those who progress to leprosy (progresso
Externí odkaz:
https://doaj.org/article/0f9f5c8c210446449b43c08d705e8e64
Autor:
Bharati Jadhav, Ramin Monajemi, Kristina K. Gagalova, Daniel Ho, Harmen H. M. Draisma, Mark A. van de Wiel, Lude Franke, Bastiaan T. Heijmans, Joyce van Meurs, Rick Jansen, GoNL Consortium, BIOS Consortium, Peter A. C. ‘t Hoen, Andrew J. Sharp, Szymon M. Kiełbasa
Publikováno v:
BMC Biology, Vol 17, Iss 1, Pp 1-20 (2019)
Abstract Background Identification of imprinted genes, demonstrating a consistent preference towards the paternal or maternal allelic expression, is important for the understanding of gene expression regulation during embryonic development and of the
Externí odkaz:
https://doaj.org/article/ac49695a15374f9b92412458d4082fc2
Autor:
Cyriel S. Olie, Muhammad Riaz, Rebecca Konietzny, Philip D. Charles, Adan Pinto-Fernandez, Szymon M. Kiełbasa, A. Aartsma-Rus, Jelle J. Goeman, Benedikt M. Kessler, Vered Raz
Publikováno v:
iScience, Vol 12, Iss , Pp 318-332 (2019)
Summary: Reduced poly(A)-binding protein nuclear 1 (PABPN1) levels cause aging-associated muscle wasting. PABPN1 is a multifunctional regulator of mRNA processing. To elucidate the molecular mechanisms causing PABPN1-mediated muscle wasting, we compa
Externí odkaz:
https://doaj.org/article/5dae7c2a66fa4fae87860ea79e03a0f4
Autor:
Said el Bouhaddani, Hae-Won Uh, Geurt Jongbloed, Caroline Hayward, Lucija Klarić, Szymon M. Kiełbasa, Jeanine Houwing-Duistermaat
Publikováno v:
BMC Bioinformatics, Vol 19, Iss 1, Pp 1-9 (2018)
Abstract Background With the exponential growth in available biomedical data, there is a need for data integration methods that can extract information about relationships between the data sets. However, these data sets might have very different char
Externí odkaz:
https://doaj.org/article/fc230314107d4557be678f1b079e3d7a
Autor:
Marvyn T. Koning, Ignis J. M. Trollmann, Cornelis A. M. van Bergen, Diego Alvarez Saravia, Marcelo A. Navarrete, Szymon M. Kiełbasa, Hendrik Veelken
Publikováno v:
Frontiers in Immunology, Vol 10 (2019)
IgE-mediated allergic disease represents an increasing health problem. Although numerous studies have investigated IgE sequences in allergic patients, little information is available on the healthy IgE repertoire. IgM, IgG, IgA, and IgE transcripts f
Externí odkaz:
https://doaj.org/article/2e67a354e1e143a1bd025b7bc65c4aa7
Autor:
Laure Grand Moursel, Willeke M. C. van Roon-Mom, Szymon M. Kiełbasa, Hailiang Mei, Henk P. J. Buermans, Linda M. van der Graaf, Kristina M. Hettne, Emile J. de Meijer, Sjoerd G. van Duinen, Jeroen F. J. Laros, Mark A. van Buchem, Peter A. C. ‘t Hoen, Silvère M. van der Maarel, Louise van der Weerd
Publikováno v:
Frontiers in Aging Neuroscience, Vol 10 (2018)
Hereditary cerebral hemorrhage with amyloidosis-Dutch type (HCHWA-D) is an early onset hereditary form of cerebral amyloid angiopathy (CAA) caused by a point mutation resulting in an amino acid change (NP_000475.1:p.Glu693Gln) in the amyloid precurso
Externí odkaz:
https://doaj.org/article/bb384dd1bf644b69bf85798bd6d2e5e9
Autor:
Roberta Rovito, Hans-Jörg Warnatz, Szymon M Kiełbasa, Hailiang Mei, Vyacheslav Amstislavskiy, Ramon Arens, Marie-Laure Yaspo, Hans Lehrach, Aloys C M Kroes, Jelle J Goeman, Ann C T M Vossen
Publikováno v:
PLoS ONE, Vol 13, Iss 7, p e0200652 (2018)
Congenital Cytomegalovirus infection (cCMV) is the leading infection in determining permanent long-term impairments (LTI), and its pathogenesis is largely unknown due to the complex interplay between viral, maternal, placental, and child factors. The
Externí odkaz:
https://doaj.org/article/d0aec4e74df94aa6afe02fab2c3e2ce1