Zobrazeno 1 - 10
of 63
pro vyhledávání: '"Szklanna P"'
Autor:
Luisa Weiss, Hayley MacLeod, Shane P. Comer, Sarah Cullivan, Paulina B. Szklanna, Fionnuala Ní Áinle, Barry Kevane, Patricia B. Maguire
Publikováno v:
STAR Protocols, Vol 4, Iss 2, Pp 102150- (2023)
Summary: The contents of the platelet releasate (PR) play significant roles in hemostasis, inflammation, and pathologic sequelae. Careful platelet isolation to ensure quiescence and subsequent activation is key to the successful generation of PR. Her
Externí odkaz:
https://doaj.org/article/c2866b26ba16494e90d809ab4b951d49
Autor:
Anne-Katrin Rohlfing, Kyra Kolb, Manuel Sigle, Melanie Ziegler, Alexander Bild, Patrick Münzer, Jessica Sudmann, Valerie Dicenta, Tobias Harm, Mailin-Christin Manke, Sascha Geue, Marcel Kremser, Madhumita Chatterjee, Chunguang Liang, Hendrik von Eysmondt, Thomas Dandekar, David Heinzmann, Manina Günter, Saskia von Ungern-Sternberg, Manuela Büttcher, Tatsiana Castor, Stine Mencl, Friederike Langhauser, Katharina Sies, Diyaa Ashour, Mustafa Caglar Beker, Michael Lämmerhofer, Stella E. Autenrieth, Tilman E. Schäffer, Stefan Laufer, Paulina Szklanna, Patricia Maguire, Matthias Heikenwalder, Karin Anne Lydia Müller, Dirk M. Hermann, Ertugrul Kilic, Ralf Stumm, Gustavo Ramos, Christoph Kleinschnitz, Oliver Borst, Harald F. Langer, Dominik Rath, Meinrad Gawaz
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-20 (2022)
ACKR3 is a critical regulator of platelet-mediated thrombosis and organ injury following ischemia/reperfusion. Platelet ACKR3 surface expression is independently associated with all-cause mortality in patients with cardiovascular diseases.
Externí odkaz:
https://doaj.org/article/bff45f142b4844968bc8a69ceae8231a
Autor:
Signe E. Cremer, James L. Catalfamo, Robert Goggs, Stefan E. Seemann, Annemarie T. Kristensen, Paulina B. Szklanna, Patricia B. Maguire, Marjory B. Brooks
Publikováno v:
Research and Practice in Thrombosis and Haemostasis, Vol 5, Iss 1, Pp 55-68 (2021)
Abstract Background Domestic dogs represent a translational animal model to study naturally occurring human disease. Proteomics has emerged as a promising tool for characterizing human platelet pathophysiology; thus a detailed characterization of the
Externí odkaz:
https://doaj.org/article/14310a91d0e74aff9e4e5f25ab057422
Akademický článek
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Autor:
Shane P. Comer, Ana Le Chevillier, Paulina B. Szklanna, Sarah Kelliher, Khalid Saeed, Steven Cullen, Osasere Edebiri, Tiina O'Neill, Niamh Stephens, Luisa Weiss, Claire A. Murphy, Saraswathi Rajakumar, Alexandra Tierney, Conor Hughes, Áine Lennon, Niamh Moran, Patricia B. Maguire, Fionnuala Ní Áinle, Barry Kevane
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 9 (2022)
BackgroundVaccine-induced thrombotic thrombocytopenia (VITT) post SARS-CoV-2 vaccination is characterized by thrombocytopenia and severe thrombosis. Platelet function during patient recovery in the medium-/long-term has not been investigated fully. H
Externí odkaz:
https://doaj.org/article/e43da276dd40457692b1c34616144286
Autor:
Paulina B. Szklanna, Haidar Altaie, Shane P. Comer, Sarah Cullivan, Sarah Kelliher, Luisa Weiss, John Curran, Emmet Dowling, Katherine M. A. O'Reilly, Aoife G. Cotter, Brian Marsh, Sean Gaine, Nick Power, Áine Lennon, Brian McCullagh, Fionnuala Ní Áinle, Barry Kevane, Patricia B. Maguire
Publikováno v:
Frontiers in Medicine, Vol 8 (2021)
To date, coronavirus disease 2019 (COVID-19) has affected over 100 million people globally. COVID-19 can present with a variety of different symptoms leading to manifestation of disease ranging from mild cases to a life-threatening condition requirin
Externí odkaz:
https://doaj.org/article/957d82295fb24aafa305e7006afba53e
Autor:
Shane P Comer, Sarah Cullivan, Paulina B Szklanna, Luisa Weiss, Steven Cullen, Sarah Kelliher, Albert Smolenski, Claire Murphy, Haidar Altaie, John Curran, Katherine O'Reilly, Aoife G Cotter, Brian Marsh, Sean Gaine, Patrick Mallon, Brian McCullagh, Niamh Moran, Fionnuala Ní Áinle, Barry Kevane, Patricia B Maguire, COCOON Study investigators
Publikováno v:
PLoS Biology, Vol 19, Iss 2, p e3001109 (2021)
Coronavirus Disease 2019 (COVID-19), caused by the novel Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2), has affected over 30 million globally to date. Although high rates of venous thromboembolism and evidence of COVID-19-induced endot
Externí odkaz:
https://doaj.org/article/accff9fda6ad4f21a599f41124fa2796
Autor:
Patricia B. Maguire, Martin E. Parsons, Paulina B. Szklanna, Monika Zdanyte, Patrick Münzer, Madhumita Chatterjee, Kieran Wynne, Dominik Rath, Shane P. Comer, Melanie Hayden, Fionnuala Ní Áinle, Meinrad Gawaz
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 7 (2020)
Upon activation, platelets release a host of soluble and vesicular signals, collectively termed the “platelet releasate” (PR). The contents of this PR play a significant role in haemostasis, inflammation, and pathologic sequelae. Despite this, pr
Externí odkaz:
https://doaj.org/article/54d7a47a1c8a471197c7d69f0ca6437b
Autor:
Rosalia Grande, Melania Dovizio, Simone Marcone, Paulina B. Szklanna, Annalisa Bruno, H. Alexander Ebhardt, Hilary Cassidy, Fionnuala Ní Áinle, Anna Caprodossi, Paola Lanuti, Marco Marchisio, Geltrude Mingrone, Patricia B. Maguire, Paola Patrignani
Publikováno v:
Frontiers in Pharmacology, Vol 10 (2019)
Rationale: Obesity is a risk factor for atherothrombosis and various cancers. However, the mechanisms are not yet completely clarified.Objectives: We aimed to verify whether the microparticles (MPs) released from thrombin-activated platelets differed
Externí odkaz:
https://doaj.org/article/6d7e099b74d74b9aaf8873d2be5b2e59
Autor:
Weiss, L., Szklanna, P., Kelliher, S., Wynne, K., Blanco, A., O’Doherty, A., Kevane, B., Zivny, J., Murphy, S., O’Donnell, M., Ní Áinle, F., Maguire, P.
Publikováno v:
In Research and Practice in Thrombosis and Haemostasis October 2023 7 Supplement 2