Novel Xanthone Derivatives Impair Growth and Invasiveness of Colon Cancer Cells In Vitro.

Autor: Rech J; Department of Biotechnology and Genetic Engineering, Faculty of Pharmaceutical Sciences in Sosnowiec, Medical University of Silesia, 40-055 Katowice, Poland., Sypniewski D; Department of Biotechnology and Genetic Engineering, Faculty of Pharmaceutical Sciences in Sosnowiec, Medical University of Silesia, 40-055 Katowice, Poland., Żelaszczyk D; Department of Bioorganic Chemistry, Faculty of Pharmacy, Jagiellonian University Medical College, 30-688 Krakow, Poland., Szkaradek N; Department of Bioorganic Chemistry, Faculty of Pharmacy, Jagiellonian University Medical College, 30-688 Krakow, Poland., Rogóż W; Department of Physical Pharmacy, Faculty of Pharmaceutical Sciences in Sosnowiec, Medical University of Silesia, 40-055 Katowice, Poland., Waszkielewicz A; Department of Bioorganic Chemistry, Faculty of Pharmacy, Jagiellonian University Medical College, 30-688 Krakow, Poland., Marona H; Department of Bioorganic Chemistry, Faculty of Pharmacy, Jagiellonian University Medical College, 30-688 Krakow, Poland., Bednarek I; Department of Biotechnology and Genetic Engineering, Faculty of Pharmaceutical Sciences in Sosnowiec, Medical University of Silesia, 40-055 Katowice, Poland.

Publikováno v: Biomolecules [Biomolecules] 2021 Oct 07; Vol. 11 (10). Date of Electronic Publication: 2021 Oct 07.

The antidepressant-like activity of chiral xanthone derivatives may be mediated by 5-HT1A receptor and β-arrestin signalling.

Autor: Sałaciak K; Department of Pharmacodynamics, Jagiellonian University Medical College, Kraków, Poland., Głuch-Lutwin M; Department of Pharmacobiology, Jagiellonian University Medical College, Kraków, Poland., Siwek A; Department of Pharmacobiology, Jagiellonian University Medical College, Kraków, Poland., Szafarz M; Department of Pharmacokinetics and Physical Pharmacy, Jagiellonian University Medical College, Kraków, Poland., Kazek G; Department of Pharmacodynamics, Jagiellonian University Medical College, Kraków, Poland., Bednarski M; Department of Pharmacodynamics, Jagiellonian University Medical College, Kraków, Poland., Nowiński L; Department of Pharmacodynamics, Jagiellonian University Medical College, Kraków, Poland., Mitchell E; Strathclyde Institute of Pharmacy and Biomedical Sciences, University of Strathclyde, Glasgow, United Kingdom., Jastrzębska-Więsek M; Department of Clinical Pharmacy, Jagiellonian University Medical College Kraków, Kraków, Poland., Partyka A; Department of Clinical Pharmacy, Jagiellonian University Medical College Kraków, Kraków, Poland., Wesołowska A; Department of Clinical Pharmacy, Jagiellonian University Medical College Kraków, Kraków, Poland., Kołaczkowski M; Department of Medicinal Chemistry, Jagiellonian University Medical College Kraków, Kraków, Poland., Szkaradek N; Department of Bioorganic Chemistry, Jagiellonian University Medical College, Krakow, Poland., Marona H; Department of Bioorganic Chemistry, Jagiellonian University Medical College, Krakow, Poland., Sapa J; Department of Pharmacodynamics, Jagiellonian University Medical College, Kraków, Poland., Pytka K; Department of Pharmacodynamics, Jagiellonian University Medical College, Kraków, Poland.

Publikováno v: Journal of psychopharmacology (Oxford, England) [J Psychopharmacol] 2020 Dec; Vol. 34 (12), pp. 1431-1442. Date of Electronic Publication: 2020 Oct 24.

Hyperthermia Intensifies α-Mangostin and Synthetic Xanthones' Antimalignancy Properties.

Autor: Rech, Jakub¹ (AUTHOR) ibednarek@sum.edu.pl, Żelaszczyk, Dorota² (AUTHOR) dorota.zelaszczyk@uj.edu.pl, Marona, Henryk² (AUTHOR) henryk.marona@uj.edu.pl, Gunia-Krzyżak, Agnieszka² (AUTHOR) agnieszka.gunia@uj.edu.pl, Żmudzki, Paweł³ (AUTHOR) pawel.zmudzki@uj.edu.pl, Bednarek, Ilona Anna¹ (AUTHOR)

Publikováno v: International Journal of Molecular Sciences. Aug2024, Vol. 25 Issue 16, p8874. 21p.

Ethanolic Extracts of Cupressaceae Species Conifers Provide Rapid Protection against Barium Chloride-Induced Cardiac Arrhythmia.

Autor: Zeng, Meng-Ting¹ (AUTHOR) 18859868050@163.com, Huang, Li-Yue¹ (AUTHOR) hly0915@163.com, Zheng, Xiao-Hui¹ (AUTHOR) 201500010365@xmmc.edu.cn, Fu, Yan-Qi¹ (AUTHOR) xmepb1@163.com, Weng, Ching-Feng^1,2,3 (AUTHOR) cfwengcf@gmail.com

Publikováno v: Pharmaceuticals (14248247). Aug2024, Vol. 17 Issue 8, p1003. 19p.

Preliminary antifungal activity assay of selected chlorine-containing derivatives of xanthone and phenoxyethyl amines.

Autor: Klesiewicz K; Department of Pharmaceutical Microbiology, Faculty of Pharmacy, Jagiellonian University Medical College, Kraków, Poland., Żelaszczyk D; Department of Bioorganic Chemistry, Chair of Organic Chemistry, Faculty of Pharmacy, Jagiellonian University Medical College, Kraków, Poland., Trojanowska D; Department of Pharmaceutical Microbiology, Faculty of Pharmacy, Jagiellonian University Medical College, Kraków, Poland., Bogusz B; Microbiological Laboratory, Department of Laboratory Diagnostics, Ludwik Rydygier Memorial Hospital, Kraków, Poland., Małek M; Department of Pharmaceutical Microbiology, Faculty of Pharmacy, Jagiellonian University Medical College, Kraków, Poland., Waszkielewicz A; Department of Bioorganic Chemistry, Chair of Organic Chemistry, Faculty of Pharmacy, Jagiellonian University Medical College, Kraków, Poland., Szkaradek N; Department of Bioorganic Chemistry, Chair of Organic Chemistry, Faculty of Pharmacy, Jagiellonian University Medical College, Kraków, Poland., Karczewska E; Department of Pharmaceutical Microbiology, Faculty of Pharmacy, Jagiellonian University Medical College, Kraków, Poland., Marona H; Department of Bioorganic Chemistry, Chair of Organic Chemistry, Faculty of Pharmacy, Jagiellonian University Medical College, Kraków, Poland., Budak A; Department of Pharmaceutical Microbiology, Faculty of Pharmacy, Jagiellonian University Medical College, Kraków, Poland.

Publikováno v: Chemical biology & drug design [Chem Biol Drug Des] 2018 Nov; Vol. 92 (5), pp. 1867-1875. Date of Electronic Publication: 2018 Jul 04.