Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Szilvia Juhász"'
Publikováno v:
Cells, Vol 12, Iss 18, p 2219 (2023)
Genome stability in human cells relies on the efficient repair of double-stranded DNA breaks, which is mainly achieved by homologous recombination (HR). Among the regulators of various cellular functions, Protein phosphatase 4 (PP4) plays a pivotal r
Externí odkaz:
https://doaj.org/article/dcb9889c9d9f424bbadfd57c4bfaa260
Publikováno v:
Molecular & Cellular Oncology, Vol 5, Iss 5 (2018)
Chromatin remodeling is critical for the regulation of the DNA damage response. We highlight findings from our recent study showing that the deposition of the histone variant H3.3 by the alpha-thalassemia mental retardation X-linked protein (ATRX) an
Externí odkaz:
https://doaj.org/article/d9c5afd83c454a02b1027a6f7e8a658d
Autor:
Lili Hegedus, Agnes Toth, Gabor M. Harami, Janos Palinkas, Nargis Karatayeva, Eniko Sajben-Nagy, Szabolcs Bene, Sara Afzali Jaktajdinani, Mihaly Kovacs, Szilvia Juhasz, Peter Burkovics
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-12 (2024)
Abstract Genome replication is frequently impeded by highly stable DNA secondary structures, including G-quadruplex (G4) DNA, that can hinder the progression of the replication fork. Human WRNIP1 (Werner helicase Interacting Protein 1) associates wit
Externí odkaz:
https://doaj.org/article/ef8693911000466fb2cdcfe50eeb72f6
Publikováno v:
Molecular & Cellular Oncology
Chromatin remodeling is critical for the regulation of the DNA damage response. We highlight findings from our recent study showing that the deposition of the histone variant H3.3 by the alpha-thalassemia mental retardation X-linked protein (ATRX) an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fd0932fd35a46df25788dde2aba7455f
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America
Significance Homologous recombination (HR) repairs DNA double-strand breaks by using a homologous template to retrieve sequence information lost at the break site. The broken DNA molecule first engages with the homologous donor molecule and is then s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0c4eb8b5726da6deebb5ca01f24b3ee3
Publikováno v:
Molecular cell. 71(1)
ATRX is a chromatin remodeler that, together with its chaperone DAXX, deposits the histone variant H3.3 in pericentromeric and telomeric regions. Notably, ATRX is frequently mutated in tumors that maintain telomere length by a specific form of homolo
Autor:
Bill Jelen, Szilvia Juhasz
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