Improved N-phenylpyrrolamide inhibitors of DNA gyrase as antibacterial agents for high-priority bacterial strains

Autor: Zidar, Nace, Onali, Alessia, Peršolja, Peter, Benedetto Tiz, Davide, Dernovšek, Jaka, Skok, Žiga, Durcik, Martina, Cotman, Andrej Emanuel, Hrast Rambaher, Martina, Cruz, Cristina D., Tammela, Päivi, Senerovic, Lidija, Jovanovic, Milija, Szili, Petra Éva, Czikkely, Márton Simon, Pál, Csaba, Zega, Anamarija, Peterlin Mašič, Lucija, Ilaš, Janez, Tomašič, Tihomir, Kikelj, Danijel

Publikováno v: In European Journal of Medicinal Chemistry 15 November 2024 278

New dual ATP-competitive inhibitors of bacterial DNA gyrase and topoisomerase IV active against ESKAPE pathogens

Autor: Durcik, Martina, Nyerges, Ákos, Skok, Žiga, Skledar, Darja Gramec, Trontelj, Jurij, Zidar, Nace, Ilaš, Janez, Zega, Anamarija, Cruz, Cristina D., Tammela, Päivi, Welin, Martin, Kimbung, Yengo R., Focht, Dorota, Benek, Ondřej, Révész, Tamás, Draskovits, Gábor, Szili, Petra Éva, Daruka, Lejla, Pál, Csaba, Kikelj, Danijel, Mašič, Lucija Peterlin, Tomašič, Tihomir

Publikováno v: In European Journal of Medicinal Chemistry 5 March 2021 213

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Hybrid Inhibitors of DNA Gyrase A and B: Design, Synthesis and Evaluation.

Autor: Durcik M; University of Ljubljana, Faculty of Pharmacy, Aškerčeva cesta 7, 1000 Ljubljana, Slovenia., Skok Ž; University of Ljubljana, Faculty of Pharmacy, Aškerčeva cesta 7, 1000 Ljubljana, Slovenia., Ilaš J; University of Ljubljana, Faculty of Pharmacy, Aškerčeva cesta 7, 1000 Ljubljana, Slovenia., Zidar N; University of Ljubljana, Faculty of Pharmacy, Aškerčeva cesta 7, 1000 Ljubljana, Slovenia., Zega A; University of Ljubljana, Faculty of Pharmacy, Aškerčeva cesta 7, 1000 Ljubljana, Slovenia., Szili PÉ; Synthetic and Systems Biology Unit, Institute of Biochemistry, Biological Research Centre, H-6726 Szeged, Hungary., Draskovits G; Synthetic and Systems Biology Unit, Institute of Biochemistry, Biological Research Centre, H-6726 Szeged, Hungary., Révész T; Synthetic and Systems Biology Unit, Institute of Biochemistry, Biological Research Centre, H-6726 Szeged, Hungary., Kikelj D; University of Ljubljana, Faculty of Pharmacy, Aškerčeva cesta 7, 1000 Ljubljana, Slovenia., Nyerges A; Synthetic and Systems Biology Unit, Institute of Biochemistry, Biological Research Centre, H-6726 Szeged, Hungary.; Department of Genetics, Harvard Medical School, Boston, MA 02215, USA., Pál C; Synthetic and Systems Biology Unit, Institute of Biochemistry, Biological Research Centre, H-6726 Szeged, Hungary., Mašič LP; University of Ljubljana, Faculty of Pharmacy, Aškerčeva cesta 7, 1000 Ljubljana, Slovenia., Tomašič T; University of Ljubljana, Faculty of Pharmacy, Aškerčeva cesta 7, 1000 Ljubljana, Slovenia.

Publikováno v: Pharmaceutics [Pharmaceutics] 2020 Dec 22; Vol. 13 (1). Date of Electronic Publication: 2020 Dec 22.