Zobrazeno 1 - 10
of 69
pro vyhledávání: '"Szilárd, TÓTH"'
Autor:
Szilárd Tóth, Márton F. Szlávik, Réka Mandel, Fanni Fekecs, Gábor Tusnády, Flóra Vajda, Nóra Varga, Ágota Apáti, Attila Bényei, Attila Paczal, András Kotschy, Gergely Szakács
Publikováno v:
ACS Omega, Vol 9, Iss 29, Pp 32226-32234 (2024)
Externí odkaz:
https://doaj.org/article/79a1802ae16c4eafaec39a09939a8c03
Autor:
Gábor M. Harami, János Pálinkás, Zoltán J. Kovács, Bálint Jezsó, Krisztián Tárnok, Hajnalka Harami-Papp, József Hegedüs, Lamiya Mahmudova, Nóra Kucsma, Szilárd Tóth, Gergely Szakács, Mihály Kovács
Publikováno v:
iScience, Vol 27, Iss 9, Pp 110788- (2024)
Summary: Human single-stranded DNA binding protein 1 (hSSB1/NABP2/OBFC2B) plays central roles in DNA repair. Here, we show that purified hSSB1 undergoes redox-dependent liquid-liquid phase separation (LLPS) in the presence of single-stranded DNA or R
Externí odkaz:
https://doaj.org/article/f900f8a1e9714c37a521aa897d38d7b2
Autor:
Szilárd, TÓTH1 toth.szili2@gmail.com
Publikováno v:
Papers of Hungarian Studies / Hungarologiai Kozlemenyek. 2024, Vol. 25 Issue 3, p132-147. 16p.
Autor:
Ádám Póti, Hella Gyergyák, Eszter Németh, Orsolya Rusz, Szilárd Tóth, Csenger Kovácsházi, Dan Chen, Bernadett Szikriszt, Sándor Spisák, Shunichi Takeda, Gergely Szakács, Zoltan Szallasi, Andrea L. Richardson, Dávid Szüts
Publikováno v:
Genome Biology, Vol 20, Iss 1, Pp 1-13 (2019)
Abstract Background Homologous recombination (HR) repair deficiency arising from defects in BRCA1 or BRCA2 is associated with characteristic patterns of somatic mutations. In this genetic study, we ask whether inactivating mutations in further genes
Externí odkaz:
https://doaj.org/article/8760977339c040bda5b2a0d40c280508
Publikováno v:
Letters in Drug Design & Discovery. 20:365-371
Background: α-Aminophosphonates are potentially biologically active species. Objective: We wished to compare the synthetic methods and evaluate the effect of the α- aminophosphonates on sarcoma cell lines. Methods: We investigated microwave-assiste
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::07976f3b4e3acb6b79a4567afe75619b
https://doi.org/10.2174/1570180819666220609104427
https://doi.org/10.2174/1570180819666220609104427
Autor:
Petra R. Varga, Alexandra Belovics, Péter Bagi, Szilárd Tóth, Gergely Szakács, Szilvia Bősze, Rita Szabó, László Drahos, György Keglevich
Publikováno v:
Molecules, Vol 27, Iss 7, p 2067 (2022)
An efficient method applying acyl chlorides as reagents was developed for the acylation of the hindered hydroxy group of dialkyl α-hydroxy-benzylphosphonates. The procedure did not require any catalyst. A few acylations were also performed with the
Externí odkaz:
https://doaj.org/article/aeef1e55b51e4ae3802306d75ad26299
Autor:
Andrea Angelo Pierluigi Tripodi, Szilárd Tóth, Kata Nóra Enyedi, Gitta Schlosser, Gergely Szakács, Gábor Mező
Publikováno v:
Beilstein Journal of Organic Chemistry, Vol 14, Iss 1, Pp 911-918 (2018)
Cyclic NGR peptides as homing devices are good candidates for the development of drug conjugates for targeted tumor therapy. In our previous study we reported that the Dau=Aoa-GFLGK(c[KNGRE]-GG-)-NH2 conjugate has a significant antitumor activity aga
Externí odkaz:
https://doaj.org/article/0849990b48c64223a0c380c04e568ae1
Autor:
Veronika F. S. Pape, Roberta Palkó, Szilárd Tóth, Miklós J. Szabó, Judit Sessler, György Dormán, Éva A. Enyedy, Tibor Soós, István Szatmári, Gergely Szakács
Publikováno v:
Journal of Medicinal Chemistry. 65:7729-7745
A recently proposed strategy to overcome multidrug resistance (MDR) in cancer is to target the collateral sensitivity of otherwise resistant cells. We designed a library of 120 compounds to explore the chemical space around previously identified 8-hy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c4d7a78a112b29d745d20a9625d75996
https://doi.org/10.1021/acs.jmedchem.2c00076
https://doi.org/10.1021/acs.jmedchem.2c00076
Autor:
Gergely Szakács, József Tóvári, László Cervenak, Nóra Kucsma, Dóra Türk, Veronika F.S. Pape, Kornélia Szebényi, Szilárd Tóth, András Füredi
Supplementary Figure 1: MDR-selective toxicity of NSC297366 in additional MDR cell lines
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::68443fa44c4682e40a6e723b9dd6976c
https://doi.org/10.1158/1535-7163.22508104.v1
https://doi.org/10.1158/1535-7163.22508104.v1
Autor:
Gergely Szakács, József Tóvári, László Cervenak, Nóra Kucsma, Dóra Türk, Veronika F.S. Pape, Kornélia Szebényi, Szilárd Tóth, András Füredi
Structure of the compounds analyzed in this study
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::909a5e7a4010fa963291ae12275eb74a
https://doi.org/10.1158/1535-7163.22508092
https://doi.org/10.1158/1535-7163.22508092