Zobrazeno 1 - 10
of 61
pro vyhledávání: '"Sze-Wan Shan"'
Autor:
Ka-Lok Li, Sze-Wan Shan, Fang-Yu Lin, Choi-Ying Ling, Nga-Wai Wong, Hoi-Lam Li, Wei Han, Chi-Ho To, Chi-Wai Do
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 6, p 5789 (2023)
Secretion of melatonin, a natural hormone whose receptors are present in the ciliary epithelium, displays diurnal variation in the aqueous humor (AH), potentially contributing to the regulation of intraocular pressure. This study aimed to determine t
Externí odkaz:
https://doaj.org/article/5b37ae5412a14bd78e2792ff4e2205c3
Publikováno v:
Data in Brief, Vol 31, Iss , Pp 105846- (2020)
Rho-associated coiled coil-forming protein kinase (ROCK) inhibitors represent a novel class of anti-glaucoma drugs because of their ocular hypotensive effects. However, the underlying mechanisms responsible for lowering intraocular pressure (IOP) are
Externí odkaz:
https://doaj.org/article/7997925d92c0497d9def750f6f0afd7e
Autor:
Samuel Abokyi, Sze-Wan Shan, Christie Hang-I Lam, Kirk Patrick Catral, Feng Pan, Henry Ho-Lung Chan, Chi-Ho To, Dennis Yan-Yin Tse
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 16, p 9042 (2021)
In age-related macular degeneration (AMD), hydroquinone (HQ)-induced oxidative damage in retinal pigment epithelium (RPE) is believed to be an early event contributing to dysregulation of inflammatory cytokines and vascular endothelial growth factor
Externí odkaz:
https://doaj.org/article/3ee1b183b2934800924bbe2b11b997af
Autor:
Hoi-lam Li, Sze Wan Shan, W. Daniel Stamer, King-kit Li, Henry Ho-lung Chan, Mortimer M. Civan, Chi-ho To, Thomas Chuen Lam, Chi-wai Do
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 13, p 7372 (2022)
Elevated intraocular pressure (IOP) is a major risk factor for glaucoma that results from impeded fluid drainage. The increase in outflow resistance is caused by trabecular meshwork (TM) cell dysfunction and excessive extracellular matrix (ECM) depos
Externí odkaz:
https://doaj.org/article/26c35e8fa7df4d3c965d575e752eef29
Autor:
Sze Wan Shan, Pan Feng Wang, Jimmy Ka Wai Cheung, Fengjuan Yu, Hui Zheng, Shumeng Luo, Shea Ping Yip, Chi Ho To, Thomas Chuen Lam
Publikováno v:
Molecular Omics. 18:449-459
Gene expression of the chick retina was examined during the early development of lens-induced myopia (LIM) using whole transcriptome sequencing.
Publikováno v:
Biophys J
Myopia is a common ocular disorder with significant alterations in the anterior ocular structure, including the cornea. The cell biophysical phenotype has been proposed to reflect the state of various diseases. However, the biophysical properties of
Autor:
Wing Yan Yu, Samantha Sze Wan Shan, Yamunadevi Lakshmanan, Francisca Siu Yin Wong, Kai Yip Choi, Henry Ho Lung Chan
Publikováno v:
PloS one. 17(5)
This study aimed to investigate whether use of a selective-blue-filtering (S-BF) lens can protect cultured primary porcine RPE cells against photo-irradiation. Transmittance of S-BF and UV-filtering (UVF) lenses was characterised spectrophotometrical
Autor:
Henry H. L. Chan, Samuel Abokyi, Christie Hang I Lam, Feng Pan, Dennis Y. Tse, Chi Ho To, Kirk Patrick Catral, Sze-Wan Shan
Publikováno v:
International Journal of Molecular Sciences
International Journal of Molecular Sciences, Vol 22, Iss 9042, p 9042 (2021)
Volume 22
Issue 16
International Journal of Molecular Sciences, Vol 22, Iss 9042, p 9042 (2021)
Volume 22
Issue 16
In age-related macular degeneration (AMD), hydroquinone (HQ)-induced oxidative damage in retinal pigment epithelium (RPE) is believed to be an early event contributing to dysregulation of inflammatory cytokines and vascular endothelial growth factor
Publikováno v:
Journal of cellular physiology. 236(12)
Rho-kinase (ROCK) inhibitors, a novel class of anti-glaucoma agents, act by increasing the aqueous humor outflow through the conventional trabecular meshwork pathway. However, the downstream signaling consequences of the ROCK inhibitor are not comple
Autor:
King Kit Li, Seema Banerjee, Sze Wan Shan, ChungHim So, Qing Wang, George Tang, Chi Wai Do, Feng Pan
Publikováno v:
Visual Neuroscience
Our previous research showed that increased phosphorylation of connexin (Cx)36 indicated extended coupling of AII amacrine cells (ACs) in the rod-dominant mouse myopic retina. This research will determine whether phosphorylation at serine 276 of Cx35