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Akademický článek

Computational characterization of 3' splice variants in the GFAP isoform family.

Autor: Sarah E Boyd, Betina Nair, Sze Woei Ng, Jonathan M Keith, Jacqueline M Orian

Publikováno v: PLoS ONE, Vol 7, Iss 3, p e33565 (2012)

Glial fibrillary acidic protein (GFAP) is an intermediate filament (IF) protein specific to central nervous system (CNS) astrocytes. It has been the subject of intense interest due to its association with neurodegenerative diseases, and because of gr

Externí odkaz: https://doaj.org/article/cfc5401563e948259b508298673091b6

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Adult Neural Precursor Cells from the Subventricular Zone Contribute Significantly to Oligodendrocyte Regeneration and Remyelination

Autor: Sarah Ellis, Bernard H.A. Chuang, Tobias D. Merson, Jo Anne Stratton, Sze Woei Ng, Jill Danne, Yao Lulu Xing, Trevor J. Kilpatrick, Philipp T. Röth

Publikováno v: The Journal of Neuroscience. 34:14128-14146

Parenchymal oligodendrocyte progenitor cells (pOPCs) are considered the principal cell type responsible for oligodendrogenesis and remyelinaton in demyelinating diseases. Recent studies have demonstrated that neural precursor cells (NPCs) from the ad

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2c9b181d649b0ed23ef467b6bddc08ea
https://doi.org/10.1523/jneurosci.3491-13.2014

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Targeted Ablation of Oligodendrocytes Induces Axonal Pathology Independent of Overt Demyelination

Autor: Holly S. Cate, Tobias D. Merson, Jo Anne Stratton, Trevor J. Kilpatrick, Laura Jane Oluich, Sze Woei Ng, Pankaj Sah, François Windels, Yao Lulu Xing

Publikováno v: Journal of Neuroscience. 32:8317-8330

The critical role of oligodendrocytes in producing and maintaining myelin that supports rapid axonal conduction in CNS neurons is well established. More recently, additional roles for oligodendrocytes have been posited, including provision of trophic

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a67af646f7c686cfe42a83a1ff3a8a34
https://doi.org/10.1523/jneurosci.1053-12.2012

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The astrocytic response in early experimental autoimmune encephalomyelitis occurs across both the grey and white matter compartments

Autor: Armelle Klopstein, Hong Pham, Anton A. Ramp, Sze Woei Ng, Margaret Ayers, Jacqueline M. Orian, Nectarios Klonis

Publikováno v: Journal of neuroimmunology. 208(1-2)

An unexpectedly prominent aspect of murine experimental autoimmune encephalomyelitis is pre-onset astrocyte reactivity. Further examination of this phenomenon in the spinal cord demonstrates that grey matter, as well as white matter astrocytes, chang

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7a1affb69adc174eedbc81027a3b32fe
https://pubmed.ncbi.nlm.nih.gov/19195719

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