Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Szabolcs Mayer"'
Autor:
Szabolcs Mayer, Péter Keglevich, Péter Ábrányi-Balogh, Áron Szigetvári, Miklós Dékány, Csaba Szántay, László Hazai
Publikováno v:
Molecules, Vol 25, Iss 4, p 888 (2020)
Chrysin is a naturally occurring flavonoid with mild anticancer activity. In this paper we report the synthesis of new chrysin derivatives alkylated with N-phenylchloroacetamides in position 7. A novel method was developed for the preparation of 7-am
Externí odkaz:
https://doaj.org/article/9545a6a8a59343779b95ac4d3b037628
Autor:
András Keglevich, Szabolcs Mayer, Réka Pápai, Áron Szigetvári, Zsuzsanna Sánta, Miklós Dékány, Csaba Szántay, Péter Keglevich, László Hazai
Publikováno v:
Molecules, Vol 23, Iss 10, p 2574 (2018)
Our successful work for the synthesis of cyclopropanated vinblastine and its derivatives by the Simmons–Smith reaction was followed to build up further three-membered rings into the 14,15-position of the vindoline part of the dimer alkaloid. Haloge
Externí odkaz:
https://doaj.org/article/af881658737844deb1c489859450850b
Autor:
Szabolcs Mayer, Dominika Mária Herr, Nóra Nagy, Viktória Donkó-Tóth, Péter Keglevich, Márton Weber, Miklós Dékány, László Hazai
Publikováno v:
Periodica Polytechnica Chemical Engineering. 67:316-336
Chrysin, a well-known naturally occurring flavonoid having several biological effects including antiproliferative activity, was coupled with different pharmacophore structures. Coupling was carried out with spacers of different lengths and types. Str
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::da1335b1908e3708f27bb0e1c3859e96
https://doi.org/10.3311/ppch.21919
https://doi.org/10.3311/ppch.21919
Publikováno v:
Current Organic Chemistry. 25:1224-1234
The chemistry and pharmacology of the important Vinca alkaloids such as vinblastine and vincristine used in anticancer therapy are still investigated widely. Several new derivatives, e.g., vinflunine, vinorelbine, and vindesine, have been synthesized
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e5ea250e24a0876f01372336fab3d4e0
https://doi.org/10.2174/1385272825666210216123256
https://doi.org/10.2174/1385272825666210216123256
Autor:
Csilla Sepsey Für, Viktor Ilkei, Szabolcs Mayer, Hedvig Bölcskei, András Keglevich, László Hazai, Péter Keglevich
Publikováno v:
Chemistry. 2:714-726
The antitumor indole–indoline alkaloids of the evergreen Catharanthus roseus—namely vinblastine and vincristine—are widely used in chemotherapy of cancer. Many efforts were made to synthesize more efficient derivatives with less side-effect. Th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::971476771aff420e8b1d9581a67a1e77
https://doi.org/10.3390/chemistry2030046
https://doi.org/10.3390/chemistry2030046
Publikováno v:
Medical Research Archives. 10
Vinca alkaloids used in anticancer therapy are the well-known vinblastine and vincristine as classical antitumor agents. These dimeric molecules consist of two monomers, vindoline and catharanthine, which have no particular activity on their own. The
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e93e5bac301838d30a32fc06dc6abcef
https://doi.org/10.18103/mra.v10i3.2663
https://doi.org/10.18103/mra.v10i3.2663
Autor:
Szabolcs Mayer, Nóra Nagy, Péter Keglevich, Áron Szigetvári, Miklós Dékány, Csaba Szántay Junior, László Hazai
Publikováno v:
Chemistry & Biodiversity. 19
Vinca alkaloids are well-known microtubule targeting agents, which are used against some types of cancer. Vindoline is one of the monomeric Vinca alkaloids which does not have anti-tumor effect, although its derivatives have serious impact on the fie
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::056c9324b938fdb12fbfd2c109095c48
https://doi.org/10.1002/cbdv.202100725
https://doi.org/10.1002/cbdv.202100725
Autor:
Péter Ábrányi-Balogh, László Hazai, Szabolcs Mayer, Miklós Dékány, Áron Szigetvári, Péter Keglevich, Csaba Szántay
Publikováno v:
Molecules
Volume 25
Issue 4
Molecules, Vol 25, Iss 4, p 888 (2020)
Volume 25
Issue 4
Molecules, Vol 25, Iss 4, p 888 (2020)
Chrysin is a naturally occurring flavonoid with mild anticancer activity. In this paper we report the synthesis of new chrysin derivatives alkylated with N-phenylchloroacetamides in position 7. A novel method was developed for the preparation of 7-am
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::58a5b504d7e69639de7e51958d5982f8
https://doi.org/10.3390/molecules25040888
https://doi.org/10.3390/molecules25040888
Autor:
László Hazai, Zsuzsanna Sánta, Szantay Csaba, Réka Pápai, Áron Szigetvári, Szabolcs Mayer, Miklós Dékány, Péter Keglevich, András Keglevich
Publikováno v:
Molecules
Volume 23
Issue 10
Molecules, Vol 23, Iss 10, p 2574 (2018)
Volume 23
Issue 10
Molecules, Vol 23, Iss 10, p 2574 (2018)
Our successful work for the synthesis of cyclopropanated vinblastine and its derivatives by the Simmons&ndash
Smith reaction was followed to build up further three-membered rings into the 14,15-position of the vindoline part of the dimer alkaloi
Smith reaction was followed to build up further three-membered rings into the 14,15-position of the vindoline part of the dimer alkaloi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::51fcfd0464c31c41e24ebf1715d3046e
Autor:
András, Keglevich, Szabolcs, Mayer, Réka, Pápai, Áron, Szigetvári, Zsuzsanna, Sánta, Miklós, Dékány, Csaba, Szántay, Péter, Keglevich, László, Hazai
Publikováno v:
Molecules : A Journal of Synthetic Chemistry and Natural Product Chemistry
Our successful work for the synthesis of cyclopropanated vinblastine and its derivatives by the Simmons–Smith reaction was followed to build up further three-membered rings into the 14,15-position of the vindoline part of the dimer alkaloid. Haloge
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::092bffb0bed76c36620202164a348c27
https://pubmed.ncbi.nlm.nih.gov/30304796
https://pubmed.ncbi.nlm.nih.gov/30304796