Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Szabolcs Éliás"'
Autor:
Inga Viktoria Hensel, Szabolcs Éliás, Michelle Steinhauer, Bilgenaz Stoll, Salvatore Benfatto, Wolfgang Merkt, Stefan Krienke, Hanns-Martin Lorenz, Jürgen Haas, Brigitte Wildemann, Martin Resnik-Docampo
Publikováno v:
EMBO Molecular Medicine, Vol 16, Iss 3, Pp 547-574 (2024)
Abstract Human intestinal epithelial cells are the interface between luminal content and basally residing immune cells. They form a tight monolayer that constantly secretes mucus creating a multilayered protective barrier. Alterations in this barrier
Externí odkaz:
https://doaj.org/article/b7aabe92d90649c6adf10c4fefcf4995
Autor:
Szabolcs Éliás, Clemens Wrzodek, Charlotte M. Deane, Alain C. Tissot, Stefan Klostermann, Francesca Ros
Publikováno v:
Frontiers in Bioinformatics, Vol 3 (2024)
Antibodies are generated with great diversity in nature resulting in a set of molecules, each optimized to bind a specific target. Taking advantage of their diversity and specificity, antibodies make up for a large part of recently developed biologic
Externí odkaz:
https://doaj.org/article/82c207e452cf49e4b1f72cfe95d982e4
Publikováno v:
Journal of Immunology Research, Vol 2021 (2021)
GM-CSF produced by autoreactive CD4-positive T helper cells is involved in the pathogenesis of autoimmune diseases, such as multiple sclerosis. However, the molecular regulators that establish and maintain the features of GM-CSF-positive CD4 T cells
Externí odkaz:
https://doaj.org/article/1c4d12510e5b4deab3c78d3fb5811821
Autor:
Angelika Schmidt, Francesco Marabita, Narsis A. Kiani, Catharina C. Gross, Henrik J. Johansson, Szabolcs Éliás, Sini Rautio, Matilda Eriksson, Sunjay Jude Fernandes, Gilad Silberberg, Ubaid Ullah, Urvashi Bhatia, Harri Lähdesmäki, Janne Lehtiö, David Gomez-Cabrero, Heinz Wiendl, Riitta Lahesmaa, Jesper Tegnér
Publikováno v:
BMC Biology, Vol 16, Iss 1, Pp 1-35 (2018)
Abstract Background Regulatory T cells (Tregs) expressing the transcription factor FOXP3 are crucial mediators of self-tolerance, preventing autoimmune diseases but possibly hampering tumor rejection. Clinical manipulation of Tregs is of great intere
Externí odkaz:
https://doaj.org/article/76505ec7322541c6a52ccbe7bb412266
Publikováno v:
Journal of Immunology Research, Vol 2021 (2021)
Journal of Immunology Research
Journal of Immunology Research
GM-CSF produced by autoreactive CD4-positive T helper cells is involved in the pathogenesis of autoimmune diseases, such as multiple sclerosis. However, the molecular regulators that establish and maintain the features of GM-CSF-positive CD4 T cells
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b81e1e5e163a18d4b7e404bfb304c94a
https://doi.org/10.1155/2021/8880585
https://doi.org/10.1155/2021/8880585
Autor:
Ioannis Tsamardinos, Giorgos Athineou, Vincenzo Lagani, Georgios Papoutsoglou, Jesper Tegnér, Iordanis Xanthopoulos, Szabolcs Éliás, Angelika Schmidt
Publikováno v:
Nucleic Acids Research
Flow and mass cytometry technologies can probe proteins as biological markers in thousands of individual cells simultaneously, providing unprecedented opportunities for reconstructing networks of protein interactions through machine learning algorith
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b4c8e0618689d7f79fe040556ee74d9d
Autor:
Hermann Josef Gröne, Hanns Martin Lorenz, Szabolcs Éliás, Angelika Schmidt, Peter H. Krammer, Annegret Kuhn, Regina Max, Cosima C. Rieger, Ram Kumar Venigalla
Publikováno v:
Immunologic Research. 65:551-563
Regulatory T cells (Tregs) are critical mediators of immune tolerance, yet their involvement in the autoimmune disease systemic lupus erythematosus (SLE) is incompletely understood. We analyzed CD4+ T cell subpopulations with Treg-related phenotypes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::dba16fac22e7b40bc50df8d728f43846
https://doi.org/10.1007/s12026-017-8904-4
https://doi.org/10.1007/s12026-017-8904-4
GM-CSF produced by autoreactive CD4 positive T helper cells is involved in the pathogenesis of autoimmune diseases, such as Multiple Sclerosis. However, the molecular regulators that establish and maintain the features of GM-CSF positive CD4 T cells
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::46b0d6535924f8db719ed91b07d93b85
https://doi.org/10.1101/555433
https://doi.org/10.1101/555433
Publikováno v:
Journal of Visualized Experiments.
Regulatory T cells (Tregs) are an integral part of peripheral tolerance, suppressing immune reactions against self-structures and thus preventing autoimmune diseases. Clinical approaches to adoptively transfer Tregs, or to deplete Tregs in cancer, ar
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::13f0ab36bc9d51f8ac42d4c36cc5b627
https://doi.org/10.3791/55015
https://doi.org/10.3791/55015
Publikováno v:
Frontiers in Immunology
The cytokine GM-CSF is involved in the pathogenesis of chronic inflammatory diseases such as Multiple Sclerosis. However, the environmental cues promoting differentiation of GM-CSF producing T cells are unclear. Herein, we performed a broad experimen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1922e9f1e8bf685393349b3174b6f370
https://doi.org/10.3389/fimmu.2016.00603
https://doi.org/10.3389/fimmu.2016.00603