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Neuregulin-1β Improves Uremic Cardiomyopathy and Renal Dysfunction in Rats.

Autor: Sárközy M; MEDICS Research Group, Department of Biochemistry, Albert Szent-Györgyi Medical School, University of Szeged, Szeged, Hungary.; Interdisciplinary Center of Excellence, University of Szeged, Szeged, Hungary., Watzinger S; Ludwig Boltzmann Institute for Cardiovascular Research at Center for Biomedical Research and Translational Surgery, Medical University of Vienna, Vienna, Austria., Kovács ZZA; MEDICS Research Group, Department of Biochemistry, Albert Szent-Györgyi Medical School, University of Szeged, Szeged, Hungary.; Interdisciplinary Center of Excellence, University of Szeged, Szeged, Hungary., Acar E; Ludwig Boltzmann Institute for Cardiovascular Research at Center for Biomedical Research and Translational Surgery, Medical University of Vienna, Vienna, Austria., Márványkövi F; MEDICS Research Group, Department of Biochemistry, Albert Szent-Györgyi Medical School, University of Szeged, Szeged, Hungary.; Interdisciplinary Center of Excellence, University of Szeged, Szeged, Hungary., Szűcs G; MEDICS Research Group, Department of Biochemistry, Albert Szent-Györgyi Medical School, University of Szeged, Szeged, Hungary.; Interdisciplinary Center of Excellence, University of Szeged, Szeged, Hungary., Lauber GY; Ludwig Boltzmann Institute for Cardiovascular Research at Center for Biomedical Research and Translational Surgery, Medical University of Vienna, Vienna, Austria., Galla Z; Metabolic and Newborn Screening Laboratory, Department of Pediatrics, Albert Szent-Györgyi Medical School, University of Szeged, Hungary., Siska A; Department of Laboratory Medicine, Albert Szent-Györgyi Medical School, University of Szeged, Szeged, Hungary., Földesi I; Department of Laboratory Medicine, Albert Szent-Györgyi Medical School, University of Szeged, Szeged, Hungary., Fintha A; Department of Pathology and Experimental Cancer Research, Semmelweis University, Budapest, Hungary., Kriston A; Synthetic and Systems Biology Unit, Biological Research Centre, Eötvös Loránd Research Network, Szeged, Hungary.; Single-Cell Technologies Ltd, Szeged, Hungary.; Institute for Molecular Medicine Finland (FIMM), University of Helsinki, Helsinki, Finland., Kovács F; Synthetic and Systems Biology Unit, Biological Research Centre, Eötvös Loránd Research Network, Szeged, Hungary.; Single-Cell Technologies Ltd, Szeged, Hungary.; Institute for Molecular Medicine Finland (FIMM), University of Helsinki, Helsinki, Finland., Horváth P; Synthetic and Systems Biology Unit, Biological Research Centre, Eötvös Loránd Research Network, Szeged, Hungary.; Single-Cell Technologies Ltd, Szeged, Hungary.; Institute for Molecular Medicine Finland (FIMM), University of Helsinki, Helsinki, Finland., Kővári B; Department of Pathology, Albert Szent-Györgyi Medical School, University of Szeged, Szeged, Hungary., Cserni G; Department of Pathology, Albert Szent-Györgyi Medical School, University of Szeged, Szeged, Hungary., Krenács T; Department of Pathology and Experimental Cancer Research, Semmelweis University, Budapest, Hungary., Szabó PL; Ludwig Boltzmann Institute for Cardiovascular Research at Center for Biomedical Research and Translational Surgery, Medical University of Vienna, Vienna, Austria., Szabó GT; Ludwig Boltzmann Institute for Cardiovascular Research at Center for Biomedical Research and Translational Surgery, Medical University of Vienna, Vienna, Austria., Monostori P; Metabolic and Newborn Screening Laboratory, Department of Pediatrics, Albert Szent-Györgyi Medical School, University of Szeged, Hungary., Zins K; Center for Anatomy and Cell Biology, Medical University of Vienna, Vienna, Austria., Abraham D; Center for Anatomy and Cell Biology, Medical University of Vienna, Vienna, Austria., Csont T; MEDICS Research Group, Department of Biochemistry, Albert Szent-Györgyi Medical School, University of Szeged, Szeged, Hungary.; Interdisciplinary Center of Excellence, University of Szeged, Szeged, Hungary., Pokreisz P; Ludwig Boltzmann Institute for Cardiovascular Research at Center for Biomedical Research and Translational Surgery, Medical University of Vienna, Vienna, Austria., Podesser BK; Ludwig Boltzmann Institute for Cardiovascular Research at Center for Biomedical Research and Translational Surgery, Medical University of Vienna, Vienna, Austria., Kiss A; Ludwig Boltzmann Institute for Cardiovascular Research at Center for Biomedical Research and Translational Surgery, Medical University of Vienna, Vienna, Austria.

Publikováno v: JACC. Basic to translational science [JACC Basic Transl Sci] 2023 May 31; Vol. 8 (9), pp. 1160-1176. Date of Electronic Publication: 2023 May 31 (Print Publication: 2023).

Methylation of the Hippo effector YAP by the methyltransferase SETD7 drives myocardial ischaemic injury: a translational study.

Autor: Ambrosini S; Center for Molecular Cardiology, University of Zürich, Wagistrasse 12, 8952 Schlieren, Switzerland., Montecucco F; First Clinic of Internal Medicine, Department of Internal Medicine, University of Genoa, viale Benedetto XV, 16132, Genoa, Italy.; IRCCS Ospedale Policlinico San Martino Genova-Italian Cardiovascular Network, Largo Rosanna Benzi, 10, 16132 Genova, Italy., Kolijn D; Institute of Physiology, Ruhr University, Universitätsstraße 150, 44801 Bochum, Germany.; Molecular and Experimental Cardiology, Ruhr University, Universitätsstraße 150, 44801 Bochum, Germany.; Department of Cardiology, St-Josef Hospital, Ruhr University, Gudrunstraße 56, 44791 Bochum, Germany., Pedicino D; Dipartimento di Scienze Cardiovascolari e Toraciche, Università Cattolica del Sacro Cuore, Largo Agostino Gemelli 8, 00168, Rome, Italy.; Fondazione Policlinico Universitario A. Gemelli IRCCS, Via Giuseppe Moscati, 31, 00168 Rome, Italy., Akhmedov A; Center for Molecular Cardiology, University of Zürich, Wagistrasse 12, 8952 Schlieren, Switzerland., Mohammed SA; Center for Molecular Cardiology, University of Zürich, Wagistrasse 12, 8952 Schlieren, Switzerland., Herwig M; Institute of Physiology, Ruhr University, Universitätsstraße 150, 44801 Bochum, Germany.; Molecular and Experimental Cardiology, Ruhr University, Universitätsstraße 150, 44801 Bochum, Germany.; Department of Cardiology, St-Josef Hospital, Ruhr University, Gudrunstraße 56, 44791 Bochum, Germany., Gorica E; Center for Molecular Cardiology, University of Zürich, Wagistrasse 12, 8952 Schlieren, Switzerland.; Department of Pharmacy, University of Pisa, via Bonanno, 6, I-56126 Pisa, Italy., Szabó PL; Ludwig-Boltzmann-Institute for Cardiovascular Research at the Center for Biomedical Research, Medical University of Vienna, Währinger Gürtel 18-20A-1090 Wien, Austria., Weber L; Ludwig-Boltzmann-Institute for Cardiovascular Research at the Center for Biomedical Research, Medical University of Vienna, Währinger Gürtel 18-20A-1090 Wien, Austria., Russo G; Dipartimento di Scienze Cardiovascolari e Toraciche, Università Cattolica del Sacro Cuore, Largo Agostino Gemelli 8, 00168, Rome, Italy.; Fondazione Policlinico Universitario A. Gemelli IRCCS, Via Giuseppe Moscati, 31, 00168 Rome, Italy., Vinci R; Dipartimento di Scienze Cardiovascolari e Toraciche, Università Cattolica del Sacro Cuore, Largo Agostino Gemelli 8, 00168, Rome, Italy.; Fondazione Policlinico Universitario A. Gemelli IRCCS, Via Giuseppe Moscati, 31, 00168 Rome, Italy., Matter CM; Center for Molecular Cardiology, University of Zürich, Wagistrasse 12, 8952 Schlieren, Switzerland.; University Heart Center, Cardiology, University Hospital Zurich, Rämistrasse 100, 8091 Zürich, Switzerland., Liuzzo G; Dipartimento di Scienze Cardiovascolari e Toraciche, Università Cattolica del Sacro Cuore, Largo Agostino Gemelli 8, 00168, Rome, Italy.; Fondazione Policlinico Universitario A. Gemelli IRCCS, Via Giuseppe Moscati, 31, 00168 Rome, Italy., Brown PJ; Structural Genomics Consortium, Univerity of Toronto, MaRS South Tower, Suite 700101 College Street, Toronto, ON M5G 1L7, Canada., Rossi FMV; Biomedical Research Centre, University of British Columbia, Vancouver, BC V6T 1Z3, Canada., Camici GG; Center for Molecular Cardiology, University of Zürich, Wagistrasse 12, 8952 Schlieren, Switzerland.; University Heart Center, Cardiology, University Hospital Zurich, Rämistrasse 100, 8091 Zürich, Switzerland.; Department of Research and Education, University Hospital Zurich, Rämistrasse 100, 8091 Zürich, Switzerland., Sciarretta S; Dipartimento di Scienze e Biotecnologie Medico-Chirurgiche, Sapienza Università di Roma, C.so della Repubblica, 79, 04100 Latina LT, Italy.; Department of AngioCardioNeurology, IRCCS Neuromed, Via Atinense, 18, 86077 Pozzilli IS, Italy., Beltrami AP; University of Udine, Piazzale Massimiliano Kolbe, 4, 33100 Udine, Italy.; Institute of Clinical Pathology, Academic Hospital 'Santa Maria della Misericordia', ASUFC, 33100 Udine, Italy., Crea F; Dipartimento di Scienze Cardiovascolari e Toraciche, Università Cattolica del Sacro Cuore, Largo Agostino Gemelli 8, 00168, Rome, Italy.; Fondazione Policlinico Universitario A. Gemelli IRCCS, Via Giuseppe Moscati, 31, 00168 Rome, Italy., Podesser B; Ludwig-Boltzmann-Institute for Cardiovascular Research at the Center for Biomedical Research, Medical University of Vienna, Währinger Gürtel 18-20A-1090 Wien, Austria., Lüscher TF; Center for Molecular Cardiology, University of Zürich, Wagistrasse 12, 8952 Schlieren, Switzerland.; Royal Brompton & Harefield Hospitals, Imperial College and King's College, Sydney Street, London SW3 6NP, UK., Kiss A; Ludwig-Boltzmann-Institute for Cardiovascular Research at the Center for Biomedical Research, Medical University of Vienna, Währinger Gürtel 18-20A-1090 Wien, Austria., Ruschitzka F; University Heart Center, Cardiology, University Hospital Zurich, Rämistrasse 100, 8091 Zürich, Switzerland., Hamdani N; Institute of Physiology, Ruhr University, Universitätsstraße 150, 44801 Bochum, Germany.; Molecular and Experimental Cardiology, Ruhr University, Universitätsstraße 150, 44801 Bochum, Germany.; Department of Cardiology, St-Josef Hospital, Ruhr University, Gudrunstraße 56, 44791 Bochum, Germany., Costantino S; Center for Molecular Cardiology, University of Zürich, Wagistrasse 12, 8952 Schlieren, Switzerland.; University Heart Center, Cardiology, University Hospital Zurich, Rämistrasse 100, 8091 Zürich, Switzerland., Paneni F; Center for Molecular Cardiology, University of Zürich, Wagistrasse 12, 8952 Schlieren, Switzerland.; University Heart Center, Cardiology, University Hospital Zurich, Rämistrasse 100, 8091 Zürich, Switzerland.; Department of Research and Education, University Hospital Zurich, Rämistrasse 100, 8091 Zürich, Switzerland.

Publikováno v: Cardiovascular research [Cardiovasc Res] 2023 Jan 18; Vol. 118 (17), pp. 3374-3385.

Remote Ischemic Perconditioning Ameliorates Myocardial Ischemia and Reperfusion-Induced Coronary Endothelial Dysfunction and Aortic Stiffness in Rats.

Autor: Szabó PL; Ludwig Boltzmann Institute for Cardiovascular Research at the Center for Biomedical Research, 27271Medical University of Vienna, Vienna, Austria., Dostal C; Ludwig Boltzmann Institute for Cardiovascular Research at the Center for Biomedical Research, 27271Medical University of Vienna, Vienna, Austria., Pilz PM; Ludwig Boltzmann Institute for Cardiovascular Research at the Center for Biomedical Research, 27271Medical University of Vienna, Vienna, Austria.; Stanford Cardiovascular Institute, School of Medicine, Stanford University, Stanford, CA, USA., Hamza O; Ludwig Boltzmann Institute for Cardiovascular Research at the Center for Biomedical Research, 27271Medical University of Vienna, Vienna, Austria., Acar E; Ludwig Boltzmann Institute for Cardiovascular Research at the Center for Biomedical Research, 27271Medical University of Vienna, Vienna, Austria., Watzinger S; Ludwig Boltzmann Institute for Cardiovascular Research at the Center for Biomedical Research, 27271Medical University of Vienna, Vienna, Austria., Mathew S; Ludwig Boltzmann Institute for Cardiovascular Research at the Center for Biomedical Research, 27271Medical University of Vienna, Vienna, Austria., Kager G; Division of Physiological Chemistry, Otto Loewi Research Center, 31475Medical University Graz, Graz, Austria., Hallström S; Division of Physiological Chemistry, Otto Loewi Research Center, 31475Medical University Graz, Graz, Austria., Podesser BK; Ludwig Boltzmann Institute for Cardiovascular Research at the Center for Biomedical Research, 27271Medical University of Vienna, Vienna, Austria., Kiss A; Ludwig Boltzmann Institute for Cardiovascular Research at the Center for Biomedical Research, 27271Medical University of Vienna, Vienna, Austria.

Publikováno v: Journal of cardiovascular pharmacology and therapeutics [J Cardiovasc Pharmacol Ther] 2021 Nov; Vol. 26 (6), pp. 702-713. Date of Electronic Publication: 2021 Aug 03.

Cardiovascular phenotype of the Dmd ^mdx rat - a suitable animal model for Duchenne muscular dystrophy.

Autor: Szabó PL; Ludwig Boltzmann Institute for Cardiovascular Research at Center for Biomedical Research, Medical University of Vienna, Vienna 1090, Austria., Ebner J; Department of Neurophysiology and Pharmacology, Center for Physiology and Pharmacology, Medical University of Vienna, Vienna 1090, Austria., Koenig X; Department of Neurophysiology and Pharmacology, Center for Physiology and Pharmacology, Medical University of Vienna, Vienna 1090, Austria., Hamza O; Ludwig Boltzmann Institute for Cardiovascular Research at Center for Biomedical Research, Medical University of Vienna, Vienna 1090, Austria., Watzinger S; Ludwig Boltzmann Institute for Cardiovascular Research at Center for Biomedical Research, Medical University of Vienna, Vienna 1090, Austria., Trojanek S; Center for Anatomy and Cell Biology, Medical University of Vienna, Vienna 1090, Austria., Abraham D; Center for Anatomy and Cell Biology, Medical University of Vienna, Vienna 1090, Austria., Todt H; Department of Neurophysiology and Pharmacology, Center for Physiology and Pharmacology, Medical University of Vienna, Vienna 1090, Austria., Kubista H; Department of Neurophysiology and Pharmacology, Center for Physiology and Pharmacology, Medical University of Vienna, Vienna 1090, Austria., Schicker K; Department of Neurophysiology and Pharmacology, Center for Physiology and Pharmacology, Medical University of Vienna, Vienna 1090, Austria., Remy S; INSERM, Center for Research in Transplantation and Immunology, UMR 1064, Nantes Université, F-44000 Nantes, France., Anegon I; INSERM, Center for Research in Transplantation and Immunology, UMR 1064, Nantes Université, F-44000 Nantes, France., Kiss A; Ludwig Boltzmann Institute for Cardiovascular Research at Center for Biomedical Research, Medical University of Vienna, Vienna 1090, Austria attila.kiss@meduniwien.ac.at., Podesser BK; Ludwig Boltzmann Institute for Cardiovascular Research at Center for Biomedical Research, Medical University of Vienna, Vienna 1090, Austria., Hilber K; Department of Neurophysiology and Pharmacology, Center for Physiology and Pharmacology, Medical University of Vienna, Vienna 1090, Austria.

Publikováno v: Disease models & mechanisms [Dis Model Mech] 2021 Feb 22; Vol. 14 (2). Date of Electronic Publication: 2021 Feb 22.