Zobrazeno 1 - 10
of 68
pro vyhledávání: '"Syu-Ichi Kanno"'
Autor:
Takafumi Hayashi, Syu-ichi Kanno, Chizuko Watanabe, Damiana Scuteri, Yasuyuki Agatsuma, Akiyoshi Hara, Giacinto Bagetta, Tsukasa Sakurada, Shinobu Sakurada
Publikováno v:
Biomedicines, Vol 12, Iss 6, p 1332 (2024)
A complication of diabetes is neuropathic pain, which is difficult to control with medication. We have confirmed that neuropathic pain due to mechanical allodynia in diabetic mice is mediated by a characteristic neuropeptide in the spinal cord. We ev
Externí odkaz:
https://doaj.org/article/abdde10706624f9c8ec97588b3c32c83
Autor:
Kenya Watanabe, Osamu Nakagawasai, Syu-ichi Kanno, Satoru Mitazaki, Hiroshi Onogi, Kohei Takahashi, Kei-ichiro Watanabe, Koichi Tan-No, Masaaki Ishikawa, Lalit K. Srivastava, Remi Quirion, Takeshi Tadano
Publikováno v:
Frontiers in Behavioral Neuroscience, Vol 16 (2022)
Genetic studies in humans have implicated the gene encoding neuregulin-1 (NRG-1) as a candidate susceptibility gene for schizophrenia. Furthermore, it has been suggested that NRG-1 is involved in regulating the expression and function of the N-methyl
Externí odkaz:
https://doaj.org/article/d59f1aca5adb4fd49e2d4667ba3f120f
Autor:
Syu-ichi Kanno, Takaharu Ohtake, Yuu Osanai, Kaori Kurauchi, Mayuko Ujibe, Koji Uwai, Mituhiro Takeshita, Susumu Satoh, Masaaki Ishikawa
Publikováno v:
Journal of Pharmacological Sciences, Vol 106, Iss 3, Pp 521-524 (2008)
We examined the effect of trimidox-induced apoptosis involvement of p53 in the NALM-6 cell line of acute lymphoblastic leukemia. Trimidox has been shown to increase the induction of p53. Phosphorylation of p53 protein at Ser-15 and Ser-20 residues wa
Externí odkaz:
https://doaj.org/article/0894172515e44663a0c9253c6b6beb24
Autor:
Syu-ichi Kanno, Mai Kakuta, Yasue Kitajima, Yuu Osanai, Kaori Kurauchi, Takaharu Ohtake, Mayuko Ujibe, Kouji Uwai, Mituhiro Takeshita, Masaaki Ishikawa
Publikováno v:
Journal of Pharmacological Sciences, Vol 104, Iss 3, Pp 278-281 (2007)
We examined the effect of trimidox (3,4,5-trihydroxybenzamidoxime) on the production of nitric oxide (NO) by lipopolysaccharide (LPS) in mouse RAW 264.7 macrophages. Trimidox (50 – 300 µM) concentration-dependently inhibited NO production by LPS (
Externí odkaz:
https://doaj.org/article/df8f35e7ff704caa9132d5502894f851
Publikováno v:
Journal of Pharmacological Sciences, Vol 92, Iss 2, Pp 166-170 (2003)
Flavonoids are widely recognized as naturally occurring antioxidants. Naringin (NG) is one of the flavonoid components in citrus fruits such as grapefruit. Hydrogen peroxide (H2O2) causes cytotoxicity through oxidative stress and apoptosis. In this p
Externí odkaz:
https://doaj.org/article/d1a90bcd19d7481c86f40422176fd937
Autor:
Syu-ichi Kanno, Akiyoshi Hara
Cardiotoxicity is a severe side effect of the potent chemotherapeutic agent doxorubicin (DOX). We recently showed that DOX-induced cardiomyocyte apoptosis and death are attenuated by pre-induction of autophagy. Here, we aimed to assess how the autoph
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1f803d107976a52b2885a52fc36608af
https://doi.org/10.21203/rs.3.rs-2872240/v1
https://doi.org/10.21203/rs.3.rs-2872240/v1
Autor:
Syu-ichi Kanno, Akiyoshi Hara
Publikováno v:
Cardiovascular Toxicology. 22:462-476
Doxorubicin (DOX) is a potent chemotherapeutic agent; however, it causes severe heart injury via apoptosis induction in many patients. DOX-induced cardiotoxicity is attenuated by activated autophagy in the heart. We previously found that programmed c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9b28eea925ae12c99309de7e957e0d3b
https://doi.org/10.1007/s12012-022-09726-w
https://doi.org/10.1007/s12012-022-09726-w
Autor:
Defny S. Wewengkang, Henki Rotinsulu, Deiske A. Sumilat, Hiroyuki Yamazaki, Syu-Ichi Kanno, Michio Namikoshi
Publikováno v:
THE 2ND INTERNATIONAL CONFERENCE ON NATURAL SCIENCES, MATHEMATICS, APPLICATIONS, RESEARCH, AND TECHNOLOGY (ICON-SMART 2021): Materials Science and Bioinformatics for Medical, Food, and Marine Industries.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b4a20a98d777d05407bc5cd8510d4dc4
https://doi.org/10.1063/5.0119405
https://doi.org/10.1063/5.0119405
Autor:
Akiyoshi Hara, Syu-ichi Kanno
Publikováno v:
Molecular Medicine Reports
Anthracyclines, such as doxorubicin (DOX), have been widely used in the treatment of a number of different solid and hematological malignancies. However, these drugs can inflict cumulative dose‑dependent and irreversible damage to the heart, and ca
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f175d2d0623763edd75513dec8b8e2e1
http://europepmc.org/articles/PMC7723161
http://europepmc.org/articles/PMC7723161
Autor:
Takafumi Hayashi, Syu-ichi Kanno, Chizuko Watanabe, Yasuyuki Agatsuma, Akiyoshi Hara, Tsukasa Sakurada, Shinobu Sakurada
Publikováno v:
Proceedings for Annual Meeting of The Japanese Pharmacological Society. 95:2
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::88470f4aa8719d7417f3b71c12964dec
https://doi.org/10.1254/jpssuppl.95.0_2-p-128
https://doi.org/10.1254/jpssuppl.95.0_2-p-128