Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Sytske H. Moolenaar"'
Autor:
Sytske H. Moolenaar, Anne-Marie van Cappellen van Walsum, Jane Crevels, Jan G. Nijhuis, Henk W. Jongsma, Udo F. H. Engelke, Berend Oeseburg, Roel Nijland, Ron A. Wevers, Ronny A De Abreu
Publikováno v:
Pediatric Research. 52:56-63
The purpose of the study was to investigate the sequence of processes occurring during and after hypoxia-induced acidemia. We used proton nuclear magnetic resonance spectroscopy, which provides an overview of metabolites in cerebrospinal fluid (CSF),
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4747b7728d728d240b96caa58a545775
https://doi.org/10.1203/00006450-200207000-00012
https://doi.org/10.1203/00006450-200207000-00012
Autor:
Gudrun Göhlich-Ratmann, Udo F. H. Engelke, Sytske H. Moolenaar, Peter Vreken, Albert H. van Gennip, Eberhard Humpfer, Georg F. Hoffmann, C. Brautigam, André B.P. van Kuilenburg, Manfred Spraul, Ron A. Wevers, Peter Dvortsak, Thomas Voit
Publikováno v:
Magnetic Resonance in Medicine. 46:1014-1017
In this work, NMR investigations that led to the discovery of a new inborn error of metabolism, beta-ureidopropionase (UP) deficiency, are reported. 1D (1)H-NMR experiments were performed using a patient's urine. 3-Ureidopropionic acid was observed i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c2a9e86cc2b99e41a83f75ac08f71842
https://doi.org/10.1002/mrm.1289
https://doi.org/10.1002/mrm.1289
Autor:
Udo F. H. Engelke, Henk W. Jongsma, Jane Crevels, Ron A. Wevers, Berend Oeseburg, Anne-Marie van Cappellen van Walsum, Roel Nijland, Sytske H. Moolenaar, Jan G. Nijhuis
Publikováno v:
Pediatric Research. 49:698-704
In fetal lambs, severe hypoxia (SH) will lead to brain damage. Mild hypoxia (MH) is thought to be relatively safe for the fetal brain because compensating mechanisms are activated. We questioned whether MH, leading to mild acidosis, induces changes i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::19c8984359b039bf4d52b5a1a3256458
https://doi.org/10.1203/00006450-200105000-00015
https://doi.org/10.1203/00006450-200105000-00015
Autor:
Udo F. H. Engelke, Ron A. Wevers, N. G. G. M. Abeling, Sytske H. Moolenaar, Hanna Mandel, Marinus Duran
Publikováno v:
Journal of inherited metabolic disease, 24(8), 843-850. Springer Netherlands
Journal of Inherited Metabolic Disease, 24, 8, pp. 843-850
Journal of Inherited Metabolic Disease, 24, 843-850
Journal of Inherited Metabolic Disease, 24, 8, pp. 843-850
Journal of Inherited Metabolic Disease, 24, 843-850
Three urine samples from two prolidase-deficient patients were analysed using 1H NMR spectroscopy. One-dimensional 1H NMR spectra showed a characteristic pattern of overlapping resonances of the proline and hydroxyproline protons of the imidodipeptid
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::06dd20b556beb93b821c0c626fd995d2
https://doi.org/10.1023/a:1013940207973
https://doi.org/10.1023/a:1013940207973
Autor:
Albert H. van Gennip, Udo F. H. Engelke, Ries Duran, Ronney A. de Abreu, Jan G.N. de Jong, Sytske H. Moolenaar, Ron A. Wevers, C. Brautigam
Publikováno v:
Clinical Chemistry. 45:539-548
Background: The diagnosis of inborn errors of purine and pyrimidine metabolism is often difficult. We examined the potential of 1H-NMR as a tool in evaluation of patients with these disorders. Methods: We performed 1H-NMR spectroscopy on 500 and 600
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d8e75358c7eb7c9d697e05e4c7d3e610
https://doi.org/10.1093/clinchem/45.4.539
https://doi.org/10.1093/clinchem/45.4.539
Autor:
Jerry Vockley, Arend Heerschap, Jan G.N. de Jong, Jacqueline M.B. Corstiaensen, Udo F. H. Engelke, Jo Poggi-Bach, Ron A. Wevers, Sytske H. Moolenaar, Barbara A. Binzak
Publikováno v:
Clinical Chemistry. 45:459-464
Background: A38-year-old man presented with a history of fish odor (since age 5) and unusual muscle fatigue with increased serum creatine kinase. Our aim was to identify the metabolic error in this new condition.Methods: We used 1H NMR spectroscopy t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c38d24917bc2a9b1bd2b46813fb7df32
https://doi.org/10.1093/clinchem/45.4.459
https://doi.org/10.1093/clinchem/45.4.459
Publikováno v:
Annals of Clinical Biochemistry, 40, 16-24
Annals of Clinical Biochemistry, 40, pp. 16-24
Annals of Clinical Biochemistry, 40, pp. 16-24
Proton nuclear magnetic resonance (NMR) spectroscopy of body fluids has been successfully applied to the field of inborn errors of metabolism. This technique has the advantage of minimal sample pretreatment not requiring extraction or derivatization
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::33f79a883369feeb29ea143f9eb7b1be
https://pubmed.ncbi.nlm.nih.gov/12542907
https://pubmed.ncbi.nlm.nih.gov/12542907
Publikováno v:
Physician’s Guide to the Laboratory Diagnosis of Metabolic Diseases ISBN: 9783642627095
The laboratory diagnosis of inherited metabolic diseases cannot always be achieved by analysis of amino acids and organic acids alone. Often, however, additional investigations also do not lead to the diagnosis while there is a strong suspicion of a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::07b38fa50bbbcc61513d92cad0a27f72
https://doi.org/10.1007/978-3-642-55878-8_6
https://doi.org/10.1007/978-3-642-55878-8_6
Autor:
Marjo S. van der Knaap, Udo F. H. Engelke, Fokje S. M. Janssen-Zijlstra, Nanda M. Verhoeven, Petra J. W. Pouwels, Sytske H. Moolenaar, Cornelis Jakobs, Ron A. Wevers
Publikováno v:
Moolenaar, S H, Van Der Knaap, M S, Engelke, U F H, Pouwels, P J W, Janssen-Zijlstra, F S M, Verhoeven, N M, Jakobs, C & Wevers, R A 2001, ' In vivo and in vitro NMR spectroscopy reveal a putative novel inborn error involving polyol metabolism ', NMR in Biomedicine, vol. 14, no. 3, pp. 167-176 . https://doi.org/10.1002/nbm.690
NMR in Biomedicine, 14(3), 167-176. John Wiley and Sons Ltd
NMR in Biomedicine, 14(3), 167-176. John Wiley and Sons Ltd
In vivo NMR spectroscopy was performed on the brain of a patient with a leukoencephalopathy, revealing unknown resonances between 3.5 and 4.0 ppm. In addition, urine and CSF of the patient were measured using high-resolution NMR spectroscopy. Also in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::258788c2be510b9a0b60c755cef76877
https://research.vumc.nl/en/publications/f45f0e92-f4fb-4e9b-9dbb-5d2fa2131eb7
https://research.vumc.nl/en/publications/f45f0e92-f4fb-4e9b-9dbb-5d2fa2131eb7
Autor:
Udo F. H. Engelke, H. Boonstra, J.G.N. de Jong, Erik A. Boss, Ron A. Wevers, Leon F. A. G. Massuger, Sytske H. Moolenaar
Most ovarian tumors are cystic structures containing variable amounts of fluid. Several studies of ovarian cyst fluid focus on one specific metabolite using conventional assay systems. We examined the potential of (1)H-nuclear magnetic resonance spec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ac1e8e26231f6688bfdd33603301bfd7
https://doi.org/10.1002/1099-1492(200008)13:5<297::AID-NBM648>3.0.CO
https://doi.org/10.1002/1099-1492(200008)13:5<297::AID-NBM648>3.0.CO