Comparative assessment of genes driving cancer and somatic evolution in non-cancer tissues: an update of the Network of Cancer Genes (NCG) resource

Autor: Lisa Dressler, Michele Bortolomeazzi, Mohamed Reda Keddar, Hrvoje Misetic, Giulia Sartini, Amelia Acha-Sagredo, Lucia Montorsi, Neshika Wijewardhane, Dimitra Repana, Joel Nulsen, Jacki Goldman, Marc Pollitt, Patrick Davis, Amy Strange, Karen Ambrose, Francesca D. Ciccarelli

Publikováno v: Genome Biology, Vol 23, Iss 1, Pp 1-22 (2022)

Abstract Background Genetic alterations of somatic cells can drive non-malignant clone formation and promote cancer initiation. However, the link between these processes remains unclear and hampers our understanding of tissue homeostasis and cancer d

Externí odkaz: https://doaj.org/article/4b436b928b4743e792fdece120c80bb3

The Network of Cancer Genes (NCG): a comprehensive catalogue of known and candidate cancer genes from cancer sequencing screens

Autor: Dimitra Repana, Joel Nulsen, Lisa Dressler, Michele Bortolomeazzi, Santhilata Kuppili Venkata, Aikaterini Tourna, Anna Yakovleva, Tommaso Palmieri, Francesca D. Ciccarelli

Publikováno v: Genome Biology, Vol 20, Iss 1, Pp 1-12 (2019)

Abstract The Network of Cancer Genes (NCG) is a manually curated repository of 2372 genes whose somatic modifications have known or predicted cancer driver roles. These genes were collected from 275 publications, including two sources of known cancer

Externí odkaz: https://doaj.org/article/29e76a682461432a89a3f79a59e70e58

Pan-cancer detection of driver genes at the single-patient resolution

Autor: Joel Nulsen, Christopher Yau, Francesca D. Ciccarelli, Hrvoje Misetic

Publikováno v: Genome Medicine, Vol 13, Iss 1, Pp 1-14 (2021)
Nulsen, J, Misetic, H, Yau, C & Ciccarelli, F D 2021, ' Pan-cancer detection of driver genes at the single-patient resolution ', Genome medicine, vol. 13, no. 1, 12, pp. 12 . https://doi.org/10.1186/s13073-021-00830-0
Genome Medicine

Background Identifying the complete repertoire of genes that drive cancer in individual patients is crucial for precision oncology. Most established methods identify driver genes that are recurrently altered across patient cohorts. However, mapping t

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::55f6b4b3dd5d5c1f43c452913b5139ca
https://doi.org/10.1101/2020.06.12.147983

The Network of Cancer Genes (NCG): a comprehensive catalogue of known and candidate cancer genes from cancer sequencing screens

Autor: Michele Bortolomeazzi, Tommaso Palmieri, Francesca D. Ciccarelli, Joel Nulsen, Dimitra Repana, Lisa Dressler, Santhilata Kuppili Venkata, Anna Yakovleva, Aikaterini Tourna

Publikováno v: Genome Biology, Vol 20, Iss 1, Pp 1-12 (2019)
Genome Biology
Repana, D, Nulsen, J, Dressler, L, Bortolomeazzi, M, Venkata, S K, Tourna, A, Yakovleva, A, Palmieri, T & Ciccarelli, F D 2019, ' The Network of Cancer Genes (NCG) : a comprehensive catalogue of known and candidate cancer genes from cancer sequencing screens ', Genome Biology, vol. 20, no. 1, 1 . https://doi.org/10.1186/s13059-018-1612-0

The Network of Cancer Genes (NCG) is a manually curated repository of 2372 genes whose somatic modifications have known or predicted cancer driver roles. These genes were collected from 275 publications, including two sources of known cancer genes an

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::707d827652b6f44687e5d8d5982e0041
https://doi.org/10.1186/s13059-018-1612-0

Experimentally based sea urchin gene regulatory network and the causal explanation of developmental phenomenology.

Autor: Ben-Tabou de-Leon S; Division of Biology 156-29, California Institute of Technology, Pasadena, CA 91125, USA., Davidson EH; Division of Biology 156-29, California Institute of Technology, Pasadena, CA 91125, USA.

Publikováno v: Wiley interdisciplinary reviews. Systems biology and medicine [Wiley Interdiscip Rev Syst Biol Med] 2009 Sep-Oct; Vol. 1 (2), pp. 237-246.