Soft Skills Needed for Problem Understanding and Innovation Generation

Autor: Sys Zoffmann Glud

Publikováno v: Glud, S Z 2022, Soft Skills Needed for Problem Understanding and Innovation Generation . in M Friebe (ed.), Novel Innovation Design for the Future of Health : Entrepreneurial Concepts for Patient Empowerment and Health Democratization . Springer, Cham, pp. 359-367 . https://doi.org/10.1007/978-3-031-08191-0, https://doi.org/978-3-031-08191-0_28
Novel Innovation Design for the Future of Health ISBN: 9783031081903

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8b96f2e2745109120c55ec43bb1ec632
https://pure.au.dk/portal/da/publications/soft-skills-needed-for-problem-understanding-and-innovation-generation(9ecccfad-f1d4-49b0-b110-d1fd14dd772a).html

Pulmonary Gene Silencing in Transgenic EGFP Mice Using Aerosolised Chitosan/siRNA Nanoparticles

Autor: Flemming Besenbacher, Ebbe Juel Bech Nielsen, Alexander Karlas, Hridayesh Prakash, Jan Møller Nielsen, Sys Zoffmann Glud, Jonathan Merrison, Kenneth A. Howard, Daniel Becker, Thomas F. Meyer, Jørgen Kjems

Publikováno v: Nielsen, E J B, Nielsen, J M, Becker, D, Karlas, A, Prakash, H, Glud, S Z, Merrison, J, Besenbacher, F, Meyer, T F, Kjems, J & Howard, K A 2010, ' Pulmonary gene silencing in transgenic EGFP mice using aerosolised chitosan/siRNA nanoparticles ', Pharmaceutical Research, vol. 27, no. 12, pp. 2520-7 . https://doi.org/10.1007/s11095-010-0255-y

Purpose This work describes the production and application of an aerosolised formulation of chitosan nanoparticles for improved pulmonary siRNA delivery and gene silencing in mice. Methods Aerosolised chitosan/siRNA nanoparticles were pneumatically f

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2557dfb8605a567eae8abf9285415071
https://doi.org/10.1007/s11095-010-0255-y

Naked siLNA-mediated gene silencing of lung bronchoepithelium EGFP expression after intravenous administration

Autor: Jesper Wengel, Sys Zoffmann Glud, Jørgen Kjems, Jens R. Nyengaard, Frederik Dagnæs-Hansen, Kenneth A. Howard, Jesper B. Bramsen

Publikováno v: Glud, S Z, Bramsen, J B, Dagnaes-Hansen, F, Wengel, J, Howard, K A, Nyengaard, J R & Kjems, J 2009, ' Naked siLNA-mediated gene silencing of lung bronchoepithelium EGFP expression after intravenous administration ', Oligonucleotides, vol. 19, no. 2, pp. 163-8 . https://doi.org/10.1089/oli.2008.0175
Glud, S Z, Bramsen, J B, Dagnæs-Hansen, F, Wengel, J, Howard, K A, Nyengaard, J R & Kjems, J 2009, ' Naked siLNA-mediated gene silencing of lung bronchoepithelium EGFP expression after intravenous administration ', Oligonucleotides, vol. 19, no. 2, pp. 163-168 . https://doi.org/10.1089/oli.2008.0175

Udgivelsesdato: 2009-Jun The use of systemic siRNA therapeutics for RNA interference-mediated silencing of disease genes is limited by serum instability and inadequate biodistribution. We have previously reported on the EGFP gene silencing effect of

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::15a7ee3a58f40a7a16410cf04c2246fa
https://pure.au.dk/portal/da/publications/naked-silnamediated-gene-silencing-of-lung-bronchoepithelium-egfp-expression-after-intravenous-administration(8b318f30-1c95-11df-b95d-000ea68e967b).html

Naked siLNA-Mediated Gene Silencing of Lung Bronchoepithelium EGFP Expression After Intravenous Administration.

Autor: Sys Zoffmann Glud, Jesper B. Bramsen, Frederik Dagnæs-Hansen, Jesper Wengel, Kenneth Alan Howard, Jens R. Nyengaard, Jørgen Kjems

Publikováno v: Oligonucleotides; Jun2009, Vol. 19 Issue 2, p163-168, 6p

RNA interference in vitro and in vivo using a novel chitosan/siRNA nanoparticle system

Autor: Jens R. Nyengaard, Sys Zoffmann Glud, Morten Østergaard Andersen, Kenneth A. Howard, Ulrik Lytt Rahbek, Jørgen Kjems, Christian Kroun Damgaard, Flemming Besenbacher, Mads Bruun Hovgaard, Alexander Schmitz, Xiudong Liu

Publikováno v: University of Southern Denmark
Howard, K A, Rahbek, U L, Liu, X, Damgaard, C K, Glud, S Z, Andersen, M Ø, Hovgaard, M B, Schmitz, A, Nyengaard, J R, Besenbacher, F & Kjems, J 2006, ' RNA interference in Vitro and in Vivo using a novel chitosan/siRNA nanoparticle system ', Molecular Therapy, vol. 14, no. 4, pp. 476-484 . https://doi.org/10.1016/j.ymthe.2006.04.010

This work introduces a novel chitosan-based siRNA nanoparticle delivery system for RNA interference in vitro and in vivo. The formation of interpolyelectrolyte complexes between siRNA duplexes (21-mers) and chitosan polymer into nanoparticles, rangin

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b1aaf5bd30410483290ad6821d258fb0
https://portal.findresearcher.sdu.dk/en/publications/a5522b95-be1c-4a26-b932-760de1701f18