Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Syota Miyajima"'
Autor:
Yu Ohmura, Tsunehito Higashi, Utano Tomaru, Tomoki Ito, Ruka Tomatsu, Masanori Kasahara, Yuji Kuge, Syota Miyajima, Mitsuhiro Yoshioka, Akihiro Ishizu, Kei Higashikawa
Publikováno v:
The American journal of pathology. 191(1)
Alzheimer disease (AD) is a progressive neurodegenerative disorder and the most common type of dementia worldwide. There is considerable evidence of age-related disruption of proteostasis being responsible for the development of AD. The proteasome is
Autor:
Takayuki Kiuchi, Yosuke Yamada, Masanori Kasahara, Soichi Miwa, Ayako Ono, Tsunehito Higashi, Tomoki Ito, Akihiro Ishizu, Katsura Nagai, Utano Tomaru, Hirotoshi Dosaka-Akita, Yoshihiro Matsuno, Syota Miyajima, Masaharu Nishimura
Publikováno v:
Laboratory Investigation. 95:625-634
Chronic obstructive pulmonary disease (COPD) is a disease common in elderly people, characterized by progressive destruction of lung parenchyma and chronic inflammation of the airways. The pathogenesis of COPD remains unclear, but recent studies sugg
Autor:
Rikuto Kimoto, Shizuka Kiuchi, Akihiro Ishizu, Saori Konno, Syota Miyajima, Mari Onodera, Utano Tomaru, Masanori Kasahara, Shigeo Murata
Publikováno v:
Cell reports. 26(3)
Summary The thymoproteasome subunit β5t is specifically expressed in cortical thymic epithelial cells (TECs) and generates unique peptides to support positive selection. In this study, using a mouse model ubiquitously expressing β5t, we showed that