Zobrazeno 1 - 10
of 26
pro vyhledávání: '"Syota Kagawa"'
Autor:
Syota Kagawa, Katsuya Tanabe, Makoto Hiromura, Kakuyou Ogawa, Takayuki Koga, Takahiro Maeda, Kikuko Amo-Shiinoki, Hiroyuki Ochi, Yui Ichiki, Shogo Fukuyama, Saori Suzuki, Natsuki Suizu, Takaaki Ohmine, Sakurako Hamachi, Hiroshi Tsuneki, Shigeru Okuya, Toshiyasu Sasaoka, Yukio Tanizawa, Fumihiro Nagashima
Publikováno v:
Frontiers in Pharmacology, Vol 14 (2023)
Hachimijiogan (HJG) has originally been used to ameliorate a variety of symptoms associated with low ambient temperatures. However, its pharmacological action in metabolic organs remains unclear. We hypothesized that HJG may modulate metabolic functi
Externí odkaz:
https://doaj.org/article/6a843b8816024421a6964c11f6afff37
Publikováno v:
Pharmacologytherapeutics. 235
Bamboo is a medicinal plant, and has long been used as a traditional/folk medicine and a food preservative in Japan. Bamboo leaf contains many active ingredients with medicinal benefits. In particular, recent studies demonstrated that bamboo leaf ext
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d9662bb69dd306a1ae216a6e5f495366
https://pubmed.ncbi.nlm.nih.gov/35183589
https://pubmed.ncbi.nlm.nih.gov/35183589
Publikováno v:
Traditional & Kampo Medicine. 4:58-61
Cases A sudden asthma attack in patient 1, a 36-year-old man, was treated with standard anti-asthma drugs; and patient 2, a 76-year-old woman, developed asthma 6 years earlier that worsened every winter. Standard anti-asthma drugs inadequately improv
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6e85d9cd30ebee9cf683626532b1f405
https://doi.org/10.1002/tkm2.1070
https://doi.org/10.1002/tkm2.1070
Autor:
Yuki Kishida, Hideki Yoshikawa, Shizue Otsuka, Keisuke Hagihara, Junsuke Arimitsu, Miho Nakanishi, Noriko Sakashita, Syota Kagawa
Publikováno v:
Phytomedicine. 22(1):16-22
Sarcopenia is characterized by age-associated skeletal muscle atrophy and reduced muscle strength; currently, no pharmaceutical treatment is available. Go-sha-jinki-Gan (GJG) is a traditional Japanese herbal medicine that is used to alleviate various
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8265bee36b2328dd0b40a8d58d3fed1b
Autor:
Norihiko Mori, Yoshiyuki Soeda, Naoki Toyooka, Xu Wang, Shuji Hosoh, Syota Kagawa, Hiroshi Tsuneki, Toshiyasu Sasaoka, Teruko Uwano, Hayato Muranaka, Yoshinori Ichihara, Yusaku Takamura, Tsutomu Wada, Hisao Nishijo
Publikováno v:
Molecular Endocrinology. 24:1965-1977
Impairment of insulin and IGF-I signaling in the brain is one of the causes of dementia associated with diabetes mellitus and Alzheimer’s disease. However, the precise pathological processes are largely unknown. In the present study, we found that
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fee682b35492a7c578c16c1f2fbda327
https://doi.org/10.1210/me.2010-0163
https://doi.org/10.1210/me.2010-0163
Publikováno v:
Journal of Neurochemistry. 110:791-800
Indoleamine 2,3-dioxygenase (IDO) is the rate-limiting enzyme of the kynurenine pathway of tryptophan metabolism, ultimately leading to production of the excitotoxin quinolinic acid (QUIN) by monocytic cells. In the Tg2576 mouse model of Alzheimer's
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9e38c3f6402a86bd528301adbe737a57
https://doi.org/10.1111/j.1471-4159.2009.06175.x
https://doi.org/10.1111/j.1471-4159.2009.06175.x
Autor:
Saori Yaguchi, Syota Kagawa, Takeshi Oya, Hajime Ishihara, Toshiyasu Sasaoka, Hiroshi Tsuneki, Masakiyo Sasahara, Yoshiyuki Soeda, Ryo Oshita, Tsutomu Wada
Publikováno v:
Endocrinology. 149:642-650
SH2-containing inositol 5'-phosphatase 2 (SHIP2) is a 5'-lipid phosphatase hydrolyzing the phosphatidylinositol (PI) 3-kinase product PI(3,4,5)P(3) to PI(3,4)P(2) in the regulation of insulin signaling, and is shown to be increased in peripheral tiss
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f09379dc1d9cdb064f6e2412545fa5dc
https://doi.org/10.1210/en.2007-0820
https://doi.org/10.1210/en.2007-0820
Autor:
Tsutomu Wada, Hajime Ishihara, Syota Kagawa, Kiyofumi Nagira, Mariko Ikubo, Kazuhito Fukui, Toshiyasu Sasaoka, Masashi Kobayashi
Publikováno v:
Diabetes. 54:1958-1967
We investigated the role of hepatic SH2-containing inositol 5′-phosphatase 2 (SHIP2) in glucose metabolism in mice. Adenoviral vectors encoding wild-type SHIP2 (WT-SHIP2) and a dominant-negative SHIP2 (ΔIP-SHIP2) were injected via the tail vein in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::39b8deae6f46375807637a5a7eb62423
https://doi.org/10.2337/diabetes.54.7.1958
https://doi.org/10.2337/diabetes.54.7.1958
Autor:
Yuji Takei, Akiyo Yamada, Syota Kagawa, Yasushi Saga, Shizuo Machida, Hiroyuki Fujiwara, Hiroaki Nonaka, Osamu Takikawa, Mitsuaki Suzuki, Hidetoshi Akimoto
Publikováno v:
International Journal of Oncology. 38
The purpose of this study was to clarify the relationship between ovarian cancer peritoneal dissemination and indoleamine 2,3-dioxygenase (IDO) expression, and to explore the possibility of IDO-targeting molecular therapy for ovarian cancer. We trans
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::47b6dc53344e110fd93f2e0b15c99ed9
https://doi.org/10.3892/ijo_00000830
https://doi.org/10.3892/ijo_00000830