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Thrombin activates NF-kappa B through thrombin receptor and results in proliferation of vascular smooth muscle cells: role of thrombin in atherosclerosis and restenosis

Autor: Syoko Ide, Hiroshi Shin, Koichiro Shigeta, Ikuro Maruyama, Toshihiro Nakajima, Isao Kitajima, Hironori Miyahara

Publikováno v: Annals of the New York Academy of Sciences. 811

We investigated the role of thrombin in the pathogenesis in atherosclerosis and restenosis. First we examined the effect of thrombin on cultured human vascular smooth muscle cells (VSMC). We showed that thrombin acts as a mitogen on VSMC through thro

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::948ec674e52b70d578e26c214f2d3bcd
https://pubmed.ncbi.nlm.nih.gov/9186620

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