Zobrazeno 1 - 10
of 56
pro vyhledávání: '"Synthetic metabolism"'
Publikováno v:
Biotechnology for Biofuels and Bioproducts, Vol 15, Iss 1, Pp 1-19 (2022)
Abstract Global energy-related emissions, in particular carbon dioxide, are rapidly increasing. Without immediate and strong reductions across all sectors, limiting global warming to 1.5 °C and thus mitigating climate change is beyond reach. In addi
Externí odkaz:
https://doaj.org/article/6b242921b07642c89571d3ba55a97b18
Kniha
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Publikováno v:
Turlin, J, Dronsella, B, De Maria, A, Lindner, S N & Nikel, P I 2022, ' Integrated rational and evolutionary engineering of genome-reduced Pseudomonas putida strains promotes synthetic formate assimilation ', Metabolic Engineering, vol. 74, pp. 191-205 . https://doi.org/10.1016/j.ymben.2022.10.008
Formate is a promising, water-soluble C1 feedstock for biotechnology that can be efficiently produced from CO2—but formatotrophy has been engineered in only a few industrially-relevant microbial hosts. We addressed the challenge of expanding the fe
Akademický článek
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Akademický článek
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Publikováno v:
ACS Catalysis
Pardo, I, Bednar, D, Calero, P, Volke, D C, Damborský, J & Nikel, P I 2022, ' A Nonconventional Archaeal Fluorinase Identified by in Silico Mining for Enhanced Fluorine Biocatalysis ', ACS Catalysis, vol. 12, no. 11, pp. 6570-6577 . https://doi.org/10.1021/acscatal.2c01184
Pardo, I, Bednar, D, Calero, P, Volke, D C, Damborský, J & Nikel, P I 2022, ' A Nonconventional Archaeal Fluorinase Identified by in Silico Mining for Enhanced Fluorine Biocatalysis ', ACS Catalysis, vol. 12, no. 11, pp. 6570-6577 . https://doi.org/10.1021/acscatal.2c01184
Fluorinases, the only enzymes known to catalyze the transfer of fluorine to an organic molecule, are essential catalysts for the biological synthesis of valuable organofluorines. However, the few fluorinases identified so far have low turnover rates
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ca5904a6eb18362db72487dbb8ded218
https://is.muni.cz/publication/1883599
https://is.muni.cz/publication/1883599
Autor:
Diehl, Christoph
The global carbon cycle is a highly balanced exchange system of carbon between the geo-, hydro- and atmosphere. Since the industrial revolution, the combustion of fossil fuels is one of the main reasons for the shift of carbon levels towards higher c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b9f1d35863e757ed2b7a60dcaa4f37f5
CO2 is one of the main greenhouse gases driving global warming, and plays a fundamental role in the global carbon cycle. The threat posed by climate change needs to be addressed during this century, if its worst effects are to be prevented or at leas
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3b021076cb0604242646dd01bd89d7d7
Autor:
Lorena Fernández-Cabezón, Berta Rosich i Bosch, Ekaterina Kozaeva, Nicolás Gurdo, Pablo Iván Nikel
Publikováno v:
Fernández-Cabezón, L, Rosich i Bosch, B, Kozaeva, E, Gurdo, N & Nikel, P I 2022, ' Dynamic flux regulation for high-titer anthranilate production by plasmid-free, conditionally-auxotrophic strains of Pseudomonas putida ', Metabolic Engineering, vol. 73, pp. 11-25 . https://doi.org/10.1016/j.ymben.2022.05.008
Anthranilate, an intermediate of the shikimate pathway, is a high-value aromatic compound widely used as a precursor in the production of dyes, fragrances, plastics and pharmaceuticals. Traditional strategies adopted for microbial anthranilate produc
Publikováno v:
Current Opinion in Systems Biology 30 (2022)
Current Opinion in Systems Biology, 30
Current Opinion in Systems Biology, 30
Synthetic biology modifies biological systems with the aim of creating new biological parts, devices, and even organisms. Systems biology deciphers the design principles of biological systems trying to derive the mathematical logic behind biological