Zobrazeno 1 - 10
of 40
pro vyhledávání: '"Synthetic Libraries"'
Autor:
Jorge Moura-Sampaio, André F. Faustino, Remi Boeuf, Miguel A. Antunes, Stefan Ewert, Ana P. Batista
Publikováno v:
Computational and Structural Biotechnology Journal, Vol 20, Iss , Pp 2723-2727 (2022)
Next-generation sequencing (NGS) is an indispensable tool in antibody discovery projects. However, the limits on NGS read length make it difficult to reconstruct full antibody sequences from the sequencing runs, especially if the six CDRs are randomi
Externí odkaz:
https://doaj.org/article/b9e95adfa66b4585895182d224e78614
Autor:
Tom Z. Yuan, Pankaj Garg, Linya Wang, Jordan R. Willis, Eric Kwan, Ana G Lujan Hernandez, Emily Tuscano, Emily N. Sever, Erica Keane, Cinque Soto, Eric M. Mucker, Mallorie E. Fouch, Edgar Davidson, Benjamin J. Doranz, Shweta Kailasan, M. Javad Aman, Haoyang Li, Jay W. Hooper, Erica Ollmann Saphire, James E. Crowe, Qiang Liu, Fumiko Axelrod, Aaron K. Sato
Publikováno v:
mAbs, Vol 14, Iss 1 (2022)
Coronavirus disease 2019 (COVID-19) is an evolving global public health crisis in need of therapeutic options. Passive immunization of monoclonal antibodies (mAbs) represents a promising therapeutic strategy capable of conferring immediate protection
Externí odkaz:
https://doaj.org/article/b6c1901170674ee7807acd867a09110b
Autor:
Omar U. Guzmán-Bringas, Keyla M. Gómez-Castellano, Edith González-González, Juana Salinas-Trujano, Said Vázquez-Leyva, Luis Vallejo-Castillo, Sonia M. Pérez-Tapia, Juan C. Almagro
Publikováno v:
International Journal of Molecular Sciences
Volume 24
Issue 5
Pages: 4609
Volume 24
Issue 5
Pages: 4609
We recently reported the isolation and characterization of anti-SARS-CoV-2 antibodies from a phage display library built with the VH repertoire of a convalescent COVID-19 patient, paired with four naïve synthetic VL libraries. One of the antibodies,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d7d2599639508b0df637276220e08550
Akademický článek
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Autor:
Tom Z. Yuan, Pankaj Garg, Linya Wang, Jordan R. Willis, Eric Kwan, Ana G Lujan Hernandez, Emily Tuscano, Emily N. Sever, Erica Keane, Cinque Soto, Eric M. Mucker, Mallorie E. Fouch, Edgar Davidson, Benjamin J. Doranz, Shweta Kailasan, M. Javad Aman, Haoyang Li, Jay W. Hooper, Erica Ollmann Saphire, James E. Crowe, Qiang Liu, Fumiko Axelrod, Aaron K. Sato
Publikováno v:
mAbs
article-version (VoR) Version of Record
mAbs, Vol 14, Iss 1 (2022)
article-version (VoR) Version of Record
mAbs, Vol 14, Iss 1 (2022)
Coronavirus disease 2019 (COVID-19) is an evolving global public health crisis in need of therapeutic options. Passive immunization of monoclonal antibodies (mAbs) represents a promising therapeutic strategy capable of conferring immediate protection
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::01454b5bcdde59a32f20af4ed44d29d1
http://europepmc.org/articles/PMC8726723
http://europepmc.org/articles/PMC8726723
Autor:
Needels, Michael C., Jones, David G., Tate, Emily H., Heinkel, Gregory L., Kochersperger, Lynn M., Dower, William J., Barrett, Ronald W., Gallop, Mark A.
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America, 1993 Nov . 90(22), 10700-10704.
Externí odkaz:
https://www.jstor.org/stable/2363295
Autor:
Serge Muyldermans
Publikováno v:
The Febs Journal
Immune or naïve nanobody (Nb) repertoires are cloned from B lymphocytes of camelids. Alternatively, synthetic Nb libraries are generated in vitro by randomising codons forming antigen‐binding loops of a Nb scaffold. These libraries serve to retrie
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8ab8340f628bc33b895fb67883d9ad44
https://pubmed.ncbi.nlm.nih.gov/32780549
https://pubmed.ncbi.nlm.nih.gov/32780549
Akademický článek
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Akademický článek
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Autor:
Jan Steyaert, Florent Chevillard, Stanimira Hristeva, Els Pardon, Silvia Stotani, Dimitrios Tzalis, Anna Karawajczyk, Peter Kolb
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 116(23)
Forward-synthetic databases are an efficient way to enumerate chemical space. We explored here whether these databases are good sources of novel protein ligands and how many molecules are obtainable and in which time frame. Based on docking calculati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::012f3387c2ec997a2c3caf04d179ceb0
https://pubmed.ncbi.nlm.nih.gov/31113876
https://pubmed.ncbi.nlm.nih.gov/31113876