Zobrazeno 1 - 10 of 13 pro vyhledávání: '"Synthetic Gene Oscillators"'
1
Basal leakage in oscillation: Coupled transcriptional and translational control using feed-forward loops
Autor: Chao-Ping Hsu, Ching Cher Sanders Yan, Shu-Hsing Wu, Ignasius Joanito, Jhih-Wei Chu
Publikováno v: PLoS Computational Biology
PLoS Computational Biology, Vol 16, Iss 9, p e1007740 (2020)
The circadian clock is a complex system that plays many important roles in most organisms. Previously, many mathematical models have been used to sharpen our understanding of the Arabidopsis clock, which brought to light the roles of each transcripti
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dc3f87e94688d1e0585369579da690bc
http://europepmc.org/articles/PMC7494099
Zobrazit plný text záznamu
2
A dual-feedback loop model of the mammalian circadian clock for multi-input control of circadian phase
Autor: Francis J. Doyle, Lindsey S. Brown
Publikováno v: PLoS Computational Biology, Vol 16, Iss 11, p e1008459 (2020)
PLoS Computational Biology
The molecular circadian clock is driven by interlocked transcriptional-translational feedback loops, producing oscillations in the expressions of genes and proteins to coordinate the timing of biological processes throughout the body. Modeling this s
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1032d844b5cde117d0067e75ca382e1d
https://doi.org/10.1371/journal.pcbi.1008459
Zobrazit plný text záznamu
3
Computational analysis of the oscillatory behavior at the translation level induced by mRNA levels oscillations due to finite intracellular resources
Autor: Yoram Zarai, Tamir Tuller
Publikováno v: PLoS Computational Biology
PLoS Computational Biology, Vol 14, Iss 4, p e1006055 (2018)
Recent studies have demonstrated how the competition for the finite pool of available gene expression factors has important effect on fundamental gene expression aspects. In this study, based on a whole-cell model simulation of translation in S. cere
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ee0d6370b227d670f7c934bd6de5a1ad
http://europepmc.org/articles/PMC5898785
Zobrazit plný text záznamu
4
A novel optogenetically tunable frequency modulating oscillator
Autor: Tarun Mahajan, Kshitij Rai
Publikováno v: PLoS ONE
PLoS ONE, Vol 13, Iss 2, p e0183242 (2018)
Synthetic biology has enabled the creation of biological reconfigurable circuits, which perform multiple functions monopolizing a single biological machine; Such a system can switch between different behaviours in response to environmental cues. Prev
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5e9208db45f0d0c7d4d19567e83d3c3f
http://europepmc.org/articles/PMC5794059
Zobrazit plný text záznamu
5
A synthetic multi-cellular network of coupled self-sustained oscillators
Autor: Miguel Fernández-Niño, Daniel Giraldo, Ingo Dreyer, Andrés Fernando González Barrios, Judith Lucia Gomez-Porras, Catalina Arévalo-Ferro
Publikováno v: PLoS ONE, Vol 12, Iss 6, p e0180155 (2017)
PLoS ONE
Engineering artificial networks from modular components is a major challenge in synthetic biology. In the past years, single units, such as switches and oscillators, were successfully constructed and implemented. The effective integration of these pa
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a85a2527eb2022e5435ffd587b1255ce
http://europepmc.org/articles/PMC5491139?pdf=render
Zobrazit plný text záznamu
6
Non-monotonic auto-regulation in single gene circuits
Autor: Eveline Peeters, Lana Descheemaeker, Sophie de Buyl
Publikováno v: PloS one, 14 (5
PLoS ONE
PLoS ONE, Vol 14, Iss 5, p e0216089 (2019)
We theoretically study the effects of non-monotonic response curves in genetic auto-regulation by exploring the possible dynamical behaviors for such systems. Our motivation is twofold: we aim at conceiving the simplest genetic circuits for synthetic
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::872821045f5a632b02b96793139423ae
https://doi.org/10.1371/journal.pone.0216089
Zobrazit plný text záznamu
7
Multi-modality in gene regulatory networks with slow promoter kinetics
Autor: Domitilla Del Vecchio, Muhammad Ali Al-Radhawi, Eduardo D. Sontag
Publikováno v: PLoS Computational Biology
PLoS Computational Biology, Vol 15, Iss 2, p e1006784 (2019)
Phenotypical variability in the absence of genetic variation often reflects complex energetic landscapes associated with underlying gene regulatory networks (GRNs). In this view, different phenotypes are associated with alternative states of complex
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4aa00b1ba26c6230acffbe4e301a6f25
https://doi.org/10.1371/journal.pcbi.1006784
Zobrazit plný text záznamu
8
Identifying stochastic oscillations in single-cell live imaging time series using Gaussian processes
Autor: Nick E Phillips, Cerys Manning, Nancy Papalopulu, Magnus Rattray
Publikováno v: PLoS Computational Biology
PLoS Computational Biology, Vol 13, Iss 5, p e1005479 (2017)
Multiple biological processes are driven by oscillatory gene expression at different time scales. Pulsatile dynamics are thought to be widespread, and single-cell live imaging of gene expression has lead to a surge of dynamic, possibly oscillatory, d
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::258cd3701d57d7084494fa8eb97273b7
http://arxiv.org/abs/1608.06476
Zobrazit plný text záznamu
9
Promoters Architecture-Based Mechanism for Noise-Induced Oscillations in a Single-Gene Circuit
Autor: Nara Guisoni, Luis Aníbal Diambra, Diana Monteoliva
Publikováno v: CONICET Digital (CONICET)
Consejo Nacional de Investigaciones Científicas y Técnicas
instacron:CONICET
SEDICI (UNLP)
Universidad Nacional de La Plata
instacron:UNLP
PLoS ONE, Vol 11, Iss 3, p e0151086 (2016)
PLoS ONE
It is well known that single-gene circuits with negative feedback loop can lead to oscillatory gene expression when they operate with time delay. In order to generate these oscillations many processes can contribute to properly timing such delay. Her
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8bb96c1fdea0311257bb3b719312a5b5
http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0151086
Zobrazit plný text záznamu
10
Modular synthetic inverters from zinc finger proteins and small RNAs
Autor: Murat Arcak, William J. Holtz, Jay D. Keasling, Michel M. Maharbiz, Justin Hsia
Publikováno v: Hsia, J; Holtz, WJ; Maharbiz, MM; Arcak, M; & Keasling, JD. (2016). Modular synthetic inverters from zinc finger proteins and small RNAs. PLoS ONE, 11(2). doi: 10.1371/journal.pone.0149483. UC Berkeley: Retrieved from: http://www.escholarship.org/uc/item/7dk3m9wb
PLoS ONE
PloS one, vol 11, iss 2
PLoS ONE, Vol 11, Iss 2, p e0149483 (2016)
© 2016 Hsia et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are cred
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2d69549a82edab87030bc2ad8d771702
http://www.escholarship.org/uc/item/7dk3m9wb
Zobrazit plný text záznamu

Vyhledávací nástroje:

Upřesnit hledání

Omezení vyhledávání
Plný text Recenzováno Digitální knihovna AV ČR
Zdroje