Zobrazeno 1 - 10
of 2 665
pro vyhledávání: '"Synovial tissue"'
Publikováno v:
Rheumatology & Autoimmunity, Vol 4, Iss 2, Pp 99-108 (2024)
Abstract Background Rheumatoid arthritis (RA) is a chronic autoimmune inflammatory disease. Its pathogenesis is not fully understood, and early diagnosis is challenging owing to the lack of effective biomarkers. This study aimed to analyze different
Externí odkaz:
https://doaj.org/article/982ab9ccc9484ac2b18a6c7ca660567e
Autor:
JianBin Li, PengCheng Liu, YiPing Huang, Yan Wang, Jun Zhao, ZhenFang Xiong, MengXia Liu, Rui Wu
Publikováno v:
Heliyon, Vol 10, Iss 13, Pp e34088- (2024)
Objective: To examine the clinical features and synovial pathologies in rheumatoid arthritis (RA) patients across varying titers of circulating anti-citrullinated protein antibodies (ACPA). Methodology: We devised a negative pressure suction and rebo
Externí odkaz:
https://doaj.org/article/553f9ac4204b4c1faba750efeb8fb934
Autor:
Ana Belén Azuaga, Andrea Cuervo, Raquel Celis, Beatriz Frade-Sosa, Juan C. Sarmiento-Monroy, Virginia Ruiz-Esquide, José A. Gómez-Puerta, Raimon Sanmartí, Julio Ramírez
Publikováno v:
Arthritis Research & Therapy, Vol 26, Iss 1, Pp 1-8 (2024)
Abstract Background Inflammatory arthritis encompasses a group of immune-mediated diseases characterized by chronic joint inflammation. Despite having pathogenic mechanisms in common, the prognosis of rheumatoid arthritis (RA), psoriatic arthritis (P
Externí odkaz:
https://doaj.org/article/65f44a5fd44b4e708acc97ae275226ac
Autor:
Yingying Wan, Wenting Sun, Jiaxi Yang, Haonan Wang, Wenqian Wang, Wanting Ye, Guoliang Cheng, Bing Li, Jianxun Ren, Qiuai Kou
Publikováno v:
Frontiers in Pharmacology, Vol 15 (2024)
Introduction: Jinteng Qingbi granules (JTQBG), a traditional Chinese medicine formulation, are widely used for the treatment of rheumatoid arthritis (RA) due to their satisfactory therapeutic efficacy. However, the underlying mechanism of action rema
Externí odkaz:
https://doaj.org/article/aaf455e7d3d543729f8c5b8db71e10db
Autor:
Patchanika Hengtrakool, Nitigorn Leearamwat, Panjana Sengprasert, Jutamas Wongphoom, Thiamjit Chaichana, Mana Taweevisit, Srihatach Ngarmukos, Aree Tanavalee, Tanapat Palaga, Rangsima Reantragoon
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
ObjectivesIn knee osteoarthritis (OA), macrophages are the most predominant immune cells that infiltrate synovial tissues and infrapatellar fat pads (IPFPs). Both M1 and M2 macrophages have been described, but their role in OA has not been fully inve
Externí odkaz:
https://doaj.org/article/d062bc03aebf401d95c44fdbacf1e369
Publikováno v:
Cells, Vol 13, Iss 9, p 743 (2024)
Rheumatoid arthritis (RA) is a chronic autoimmune disorder which can lead to long-term joint damage and significantly reduced quality of life if not promptly diagnosed and adequately treated. Despite significant advances in treatment, about 40% of pa
Externí odkaz:
https://doaj.org/article/e4cd5b59a0904e62bcb09b8f290a2408
Autor:
Jose A. Pinto-Tasende, Mercedes Fernandez-Moreno, Ignacio Rego Perez, J. Carlos Fernandez-Lopez, Natividad Oreiro-Villar, F. Javier De Toro Santos, Francisco J. Blanco-García
Publikováno v:
Biomedicines, Vol 12, Iss 4, p 815 (2024)
Background: Delay in diagnosis and therapy in patients with arthritis commonly leads to progressive articular damage. The study aimed to investigate the immunohistochemical reactivity of synovial cytokines associated with inflammation and the bone er
Externí odkaz:
https://doaj.org/article/e7c1d5f482834e138e34651ace182f0d
Autor:
Runrun Zhang, Cen Chang, Yehua Jin, LingXia Xu, Ping Jiang, Kai Wei, Linshuai Xu, Shicheng Guo, Songtao Sun, Dongyi He
Publikováno v:
Journal of Translational Medicine, Vol 20, Iss 1, Pp 1-11 (2022)
Abstract Objective To identify novel DNA methylation-regulated differentially expressed genes (MeDEGs) in RA by integrated analysis of DNA methylation and RNA-Seq data. Methods The transcription and DNA methylation profiles of 9 RA and 15 OA synovial
Externí odkaz:
https://doaj.org/article/5321914052824ac0b45b516a59b310d2
Publikováno v:
Bone & Joint Research, Vol 11, Iss 9, Pp 679-689 (2022)
AimsThis study aimed, through bioinformatics analysis, to identify the potential diagnostic markers of osteoarthritis, and analyze the role of immune infiltration in synovial tissue.MethodsThe gene expression profiles were downloaded from the Gene Ex
Externí odkaz:
https://doaj.org/article/a3321a49ef2448e8a559207d86dd8a94
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 21, p 15932 (2023)
Infection by arthritogenic alphaviruses (aavs) can lead to reactive arthritis, which is characterized by inflammation and persistence of the virus; however, its mechanisms remain ill-characterized. Intriguingly, it has been shown that viral persisten
Externí odkaz:
https://doaj.org/article/2632e526d36b49d89d3fed9ed861ee42