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pro vyhledávání: '"Synovial Membrane/cytology/metabolism"'
Autor:
Céline Foulquier, Jean-Michel Dayer, Sylvie Ferrari-Lacraz, Mireille Sebbag, Rachel Chicheportiche, Guy Serre
Publikováno v:
European Cytokine Network, Vol. 23, No 2 (2012) pp. 36-44
Objective: The antigenic targets of the rheumatoid arthritis (RA)-associated autoantibodies to “citrullinated” proteins are generated following citrullination by a peptidylarginine deiminase (PAD). Of the five PAD isotypes, two – PAD2 and PAD4