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pro vyhledávání: '"Synexpression"'
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Publikováno v:
Nature Communications
Nature Communications, Vol 11, Iss 1, Pp 1-16 (2020)
Nature Communications, Vol 11, Iss 1, Pp 1-16 (2020)
BMP signaling plays key roles in development, stem cells, adult tissue homeostasis, and disease. How BMP receptors are extracellularly modulated and in which physiological context, is therefore of prime importance. R-spondins (RSPOs) are a small fami
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::970268727c5fdf4537b4e06bdc1f6e98
https://doi.org/10.1038/s41467-020-19373-w
https://doi.org/10.1038/s41467-020-19373-w
BMP signalling plays key roles in development, stem cells, adult tissue homeostasis, and disease. How BMP receptors are extracellularly modulated and in which physiological context, is therefore of prime importance. R-spondins (RSPOs) are a small fam
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::32be66c4147a4defa5979b97c8b02dd6
https://doi.org/10.1101/2020.09.10.287607
https://doi.org/10.1101/2020.09.10.287607
Autor:
Alissa M. Hulstrand, Jeffrey C. Murray, J. Robert Manak, Robert A. Cornell, Lisa A. Lansdon, Douglas W. Houston, Abby Long, Rachel B. Brouillette, M. Adela Mansilla, Aline Petrin, Benjamin W. Darbro, Jennifer Standley
Publikováno v:
Genetics. 208:283-296
Orofacial clefts are one of the most common birth defects, affecting 1–2 per 1000 births, and have a complex etiology. High-resolution array-based comparative genomic hybridization has increased the ability to detect copy number variants (CNVs) tha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8713d29ba88b897f6f94c1fd7e6969f0
https://doi.org/10.1534/genetics.117.300535
https://doi.org/10.1534/genetics.117.300535
Publikováno v:
Advances in Sexual Medicine. :50-78
Methods: Asystematic literature search was performed using PUBMED for all English articles up to April 2014. Although this review mainly focuses on published human studies, it also draws attention to where future research should be directed based on
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::945e51375a6bfdafcaa1dab863cefc7b
https://doi.org/10.4236/asm.2016.64007
https://doi.org/10.4236/asm.2016.64007
Autor:
Fatima Wazin, Frank J. Lovicu, Charles G. Bailey, Yue Feng, Alyssa Susanto, Guannan Zhao, John E.J. Rasko
Publikováno v:
Experimental eye research. 178
Spred, like Sprouty (Spry) and also Sef proteins, have been identified as important regulators of receptor tyrosine kinase (RTK)-mediated MAPK/ERK-signaling in various developmental systems, controlling cellular processes such as proliferation, migra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::767e2565a7752905cb27ac0cfb8013a2
https://pubmed.ncbi.nlm.nih.gov/30290165
https://pubmed.ncbi.nlm.nih.gov/30290165
Autor:
Kazunobu Isogaya, Keiji Miyazawa, Masahiko Shinozaki, Ulf Hellman, Akiyoshi Komuro, Hiroaki Ikushima, Kohei Miyazono
Publikováno v:
The EMBO Journal
Transforming growth factor (TGF)-beta induces various cellular responses principally through Smad-dependent transcriptional regulation. Activated Smad complexes cooperate with transcription factors in regulating a group of target genes. The target ge
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8db258b7b39a51872ea43fe7026060e0
https://doi.org/10.1038/emboj.2008.218
https://doi.org/10.1038/emboj.2008.218
Publikováno v:
BMC Bioinformatics
BackgroundNext-generation sequencing technologies have greatly increased our ability to identify gene expression levels, including at specific developmental stages and in specific tissues. Gene expression data can help researchers understand the dive
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::57500c0bb74df57dce92a697f7e50ee7
https://pubmed.ncbi.nlm.nih.gov/28187709
https://pubmed.ncbi.nlm.nih.gov/28187709
Autor:
Nick D.L. Owens, Ilya Patrushev, Mustafa K. Khokha, Ken W.Y. Cho, Michael J. Gilchrist, Ira L. Blitz, Maura Lane, John D. Overton
Publikováno v:
Cell reports, vol 14, iss 3
Cell Reports, Vol 14, Iss 3, Pp 632-647 (2016)
Cell Reports, Vol 14, Iss 3, Pp 632-647 (2016)
Summary Transcript regulation is essential for cell function, and misregulation can lead to disease. Despite technologies to survey the transcriptome, we lack a comprehensive understanding of transcript kinetics, which limits quantitative biology. Th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::964f9bf4c8181dd8e74c27b00e947b79
https://escholarship.org/uc/item/0vj297jb
https://escholarship.org/uc/item/0vj297jb
Autor:
Rachel Robertson, Abir Mukherjee
Publikováno v:
Biochemical and Biophysical Research Communications. 427:568-573
Follistatin-like 3 (FSTL3) is a secreted glycoprotein that forms inactive complexes with and acts as an endogenous inhibitor of TGFβ ligands such as activin, myostatin and GDF11. FSTL3 gene deleted mice (FSTL3 KO) are viable, fertile and show a cons
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::01bf28601ab00ab6d3000a3e59eddd11
https://doi.org/10.1016/j.bbrc.2012.09.098
https://doi.org/10.1016/j.bbrc.2012.09.098