Cell loss in the motor and cingulate cortex correlates with symptomatology in Huntington's disease.

Autor: Thu DC, Oorschot DE, Tippett LJ, Nana AL, Hogg VM, Synek BJ, Luthi-Carter R, Waldvogel HJ, Faull RL

Publikováno v: Brain: A Journal of Neurology; Apr2010, Vol. 133 Issue 4, p1094-1110, 17p

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Symptom heterogeneity in Huntington's disease correlates with neuronal degeneration in the cerebral cortex.

Autor: Mehrabi NF; Centre for Brain Research, University of Auckland, Auckland, New Zealand; Department of Anatomy and Medical Imaging, University of Auckland, Auckland, New Zealand., Waldvogel HJ; Centre for Brain Research, University of Auckland, Auckland, New Zealand; Department of Anatomy and Medical Imaging, University of Auckland, Auckland, New Zealand., Tippett LJ; Centre for Brain Research, University of Auckland, Auckland, New Zealand; Department of Psychology, University of Auckland, Auckland, New Zealand., Hogg VM; Centre for Brain Research, University of Auckland, Auckland, New Zealand; Department of Psychology, University of Auckland, Auckland, New Zealand., Synek BJ; Centre for Brain Research, University of Auckland, Auckland, New Zealand; Forensic Pathology, Auckland City Hospital, Auckland, New Zealand., Faull RL; Centre for Brain Research, University of Auckland, Auckland, New Zealand; Department of Anatomy and Medical Imaging, University of Auckland, Auckland, New Zealand. Electronic address: rlm.faull@auckland.ac.

Publikováno v: Neurobiology of disease [Neurobiol Dis] 2016 Dec; Vol. 96, pp. 67-74. Date of Electronic Publication: 2016 Aug 25.

Elevation of brain glucose and polyol-pathway intermediates with accompanying brain-copper deficiency in patients with Alzheimer's disease: metabolic basis for dementia.

Autor: Xu J; School of Biological Sciences, and Maurice Wilkins Centre for Molecular Biodiscovery, Faculty of Science, University of Auckland, New Zealand.; Centre for Brain Research, Faculty of Medical and Health Sciences, University of Auckland, New Zealand.; Centre for Advanced Discovery and Experimental Therapeutics (CADET), Central Manchester University Hospitals NHS Foundation Trust, and Institute of Human Development, Faculty of Medical and Human Sciences, University of Manchester, United Kingdom., Begley P; Centre for Advanced Discovery and Experimental Therapeutics (CADET), Central Manchester University Hospitals NHS Foundation Trust, and Institute of Human Development, Faculty of Medical and Human Sciences, University of Manchester, United Kingdom., Church SJ; Centre for Advanced Discovery and Experimental Therapeutics (CADET), Central Manchester University Hospitals NHS Foundation Trust, and Institute of Human Development, Faculty of Medical and Human Sciences, University of Manchester, United Kingdom., Patassini S; School of Biological Sciences, and Maurice Wilkins Centre for Molecular Biodiscovery, Faculty of Science, University of Auckland, New Zealand.; Centre for Brain Research, Faculty of Medical and Health Sciences, University of Auckland, New Zealand.; Centre for Advanced Discovery and Experimental Therapeutics (CADET), Central Manchester University Hospitals NHS Foundation Trust, and Institute of Human Development, Faculty of Medical and Human Sciences, University of Manchester, United Kingdom., McHarg S; Centre for Advanced Discovery and Experimental Therapeutics (CADET), Central Manchester University Hospitals NHS Foundation Trust, and Institute of Human Development, Faculty of Medical and Human Sciences, University of Manchester, United Kingdom., Kureishy N; Centre for Advanced Discovery and Experimental Therapeutics (CADET), Central Manchester University Hospitals NHS Foundation Trust, and Institute of Human Development, Faculty of Medical and Human Sciences, University of Manchester, United Kingdom., Hollywood KA; Centre for Advanced Discovery and Experimental Therapeutics (CADET), Central Manchester University Hospitals NHS Foundation Trust, and Institute of Human Development, Faculty of Medical and Human Sciences, University of Manchester, United Kingdom., Waldvogel HJ; Centre for Brain Research, Faculty of Medical and Health Sciences, University of Auckland, New Zealand., Liu H; School of Biological Sciences, and Maurice Wilkins Centre for Molecular Biodiscovery, Faculty of Science, University of Auckland, New Zealand., Zhang S; School of Biological Sciences, and Maurice Wilkins Centre for Molecular Biodiscovery, Faculty of Science, University of Auckland, New Zealand., Lin W; Centre for Advanced Discovery and Experimental Therapeutics (CADET), Central Manchester University Hospitals NHS Foundation Trust, and Institute of Human Development, Faculty of Medical and Human Sciences, University of Manchester, United Kingdom., Herholz K; Institute of Brain, Behaviour and Mental Health, Faculty of Medical and Human Sciences, University of Manchester, United Kingdom., Turner C; Anatomical Pathology, LabPLUS, Auckland City Hospital, Auckland, New Zealand., Synek BJ; Centre for Brain Research, Faculty of Medical and Health Sciences, University of Auckland, New Zealand.; Anatomical Pathology, LabPLUS, Auckland City Hospital, Auckland, New Zealand., Curtis MA; Centre for Brain Research, Faculty of Medical and Health Sciences, University of Auckland, New Zealand., Rivers-Auty J; Institute of Brain, Behaviour and Mental Health, Faculty of Medical and Human Sciences, University of Manchester, United Kingdom., Lawrence CB; Institute of Brain, Behaviour and Mental Health, Faculty of Medical and Human Sciences, University of Manchester, United Kingdom., Kellett KA; Institute of Brain, Behaviour and Mental Health, Faculty of Medical and Human Sciences, University of Manchester, United Kingdom., Hooper NM; Institute of Brain, Behaviour and Mental Health, Faculty of Medical and Human Sciences, University of Manchester, United Kingdom., Vardy ER; Salford Royal NHS Foundation Trust, Salford, United Kingdom., Wu D; Guangzhou Institutes of Biomedicine and Health, Chinese Academy of Sciences, Guangzhou, China., Unwin RD; Centre for Advanced Discovery and Experimental Therapeutics (CADET), Central Manchester University Hospitals NHS Foundation Trust, and Institute of Human Development, Faculty of Medical and Human Sciences, University of Manchester, United Kingdom., Faull RL; Centre for Brain Research, Faculty of Medical and Health Sciences, University of Auckland, New Zealand., Dowsey AW; Centre for Advanced Discovery and Experimental Therapeutics (CADET), Central Manchester University Hospitals NHS Foundation Trust, and Institute of Human Development, Faculty of Medical and Human Sciences, University of Manchester, United Kingdom., Cooper GJ; School of Biological Sciences, and Maurice Wilkins Centre for Molecular Biodiscovery, Faculty of Science, University of Auckland, New Zealand.; Centre for Brain Research, Faculty of Medical and Health Sciences, University of Auckland, New Zealand.; Centre for Advanced Discovery and Experimental Therapeutics (CADET), Central Manchester University Hospitals NHS Foundation Trust, and Institute of Human Development, Faculty of Medical and Human Sciences, University of Manchester, United Kingdom.

Publikováno v: Scientific reports [Sci Rep] 2016 Jun 09; Vol. 6, pp. 27524. Date of Electronic Publication: 2016 Jun 09.

Widespread heterogeneous neuronal loss across the cerebral cortex in Huntington's disease.

Autor: Nana AL; Department of Anatomy with Radiology, University of Auckland, Auckland, New Zealand Centre for Brain Research, University of Auckland, Auckland, New Zealand., Kim EH; Department of Anatomy with Radiology, University of Auckland, Auckland, New Zealand Centre for Brain Research, University of Auckland, Auckland, New Zealand., Thu DC; Department of Anatomy with Radiology, University of Auckland, Auckland, New Zealand Brain Mind Institute, École Polytechnique Fédérale de Lausanne (EPFL), Lausanne, Switzerland., Oorschot DE; Department of Anatomy, Otago School of Medical Sciences, and the Brain Health Research Centre, University of Otago, Dunedin, New Zealand., Tippett LJ; Centre for Brain Research, University of Auckland, Auckland, New Zealand Department of Psychology, University of Auckland, Auckland, New Zealand., Hogg VM; Centre for Brain Research, University of Auckland, Auckland, New Zealand Department of Psychology, University of Auckland, Auckland, New Zealand., Synek BJ; Centre for Brain Research, University of Auckland, Auckland, New Zealand Department of Forensic Pathology, Auckland City Hospital, Auckland, New Zealand., Roxburgh R; Centre for Brain Research, University of Auckland, Auckland, New Zealand Department of Neurology, Auckland City Hospital, Auckland, New Zealand., Waldvogel HJ; Department of Anatomy with Radiology, University of Auckland, Auckland, New Zealand Centre for Brain Research, University of Auckland, Auckland, New Zealand., Faull RL; Department of Anatomy with Radiology, University of Auckland, Auckland, New Zealand Centre for Brain Research, University of Auckland, Auckland, New Zealand.

Publikováno v: Journal of Huntington's disease [J Huntingtons Dis] 2014; Vol. 3 (1), pp. 45-64.