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pro vyhledávání: '"Synaptic pharmacology"'
Akademický článek
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Autor:
Hanna Regus-Leidig, Anneka Joachimsthaler, Andreas Feigenspan, Martina Löhner, Johann Helmut Brandstätter, Kaspar Gierke, Jan Kremers, Susanne Schoch, Jenny Atorf, Tanja M. Müller, Henrik Martens, Angela Peukert, Norbert Babai
Publikováno v:
The Journal of Neuroscience. 37:7848-7863
RAB3A-interacting molecule (RIM) proteins are important regulators of transmitter release from active zones. At conventional chemical synapses, RIMs contribute substantially to vesicle priming and docking and their loss reduces the readily releasable
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d8a68f20d5cb4f5b72183eae70e61175
https://doi.org/10.1523/jneurosci.2795-16.2017
https://doi.org/10.1523/jneurosci.2795-16.2017
Autor:
Ulyana Lalo, Yuriy Pankratov
Publikováno v:
Cell Calcium. 64:91-101
Dynamic alteration of the synaptic strength is one of the most important processes occurring in the nervous system. Combination of electrophysiology, confocal imaging and molecular biology led to significant advances in this research field. Yet, a pr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::170f27a77b4db52d2110ba8d3706e48c
https://doi.org/10.1016/j.ceca.2017.01.008
https://doi.org/10.1016/j.ceca.2017.01.008
Autor:
Judith J.M. Jans, Nanda M. Verhoeven-Duif, Mieke M. van Haelst, Gijs van Haaften, Glen R. Monroe, Karen Duran, Katarzyna Pienkowska, Holger Taschenberger, Ron van Empelen, Timothy A. Ryan, Peter M. van Hasselt, Heleen C. Van Teeseling, Francesco Michelassi, Nathaniel Calloway, Gepke Visser, Noa Lipstein, Inge Cuppen, Jeremy S. Dittman, Olaf Jahn, Annemieke M. V. Evelein, Nils Brose, Jeong-Seop Rhee, Jacob A. S. Vorstman, Sven Thoms
Publikováno v:
Journal of Clinical Investigation
Journal of Clinical Investigation, 127(3), 1005-1018. The American Society for Clinical Investigation
Journal of clinical investigation, 127(3), 1005-1018. The American Society for Clinical Investigation
Journal of Clinical Investigation, 127(3), 1005. The American Society for Clinical Investigation
Lipstein, N, Verhoeven-Duif, N M, Michelassi, F E, Calloway, N, Van Hasselt, P M, Pienkowska, K, Van Haaften, G, Van Haelst, M M, Van Empelen, R, Cuppen, I, Van Teeseling, H C, Evelein, A M V, Vorstman, J A, Thoms, S, Jahn, O, Duran, K J, Monroe, G R, Ryan, T A, Taschenberger, H, Dittman, J S, Rhee, J S, Visser, G, Jans, J J & Brose, N 2017, ' Synaptic UNC13A protein variant causes increased neurotransmission and dyskinetic movement disorder ', Journal of Clinical Investigation, vol. 127, no. 3, pp. 1005-1018 . https://doi.org/10.1172/JCI90259
The Journal of Clinical Investigation
Journal of Clinical Investigation, 127(3), 1005-1018. The American Society for Clinical Investigation
Journal of clinical investigation, 127(3), 1005-1018. The American Society for Clinical Investigation
Journal of Clinical Investigation, 127(3), 1005. The American Society for Clinical Investigation
Lipstein, N, Verhoeven-Duif, N M, Michelassi, F E, Calloway, N, Van Hasselt, P M, Pienkowska, K, Van Haaften, G, Van Haelst, M M, Van Empelen, R, Cuppen, I, Van Teeseling, H C, Evelein, A M V, Vorstman, J A, Thoms, S, Jahn, O, Duran, K J, Monroe, G R, Ryan, T A, Taschenberger, H, Dittman, J S, Rhee, J S, Visser, G, Jans, J J & Brose, N 2017, ' Synaptic UNC13A protein variant causes increased neurotransmission and dyskinetic movement disorder ', Journal of Clinical Investigation, vol. 127, no. 3, pp. 1005-1018 . https://doi.org/10.1172/JCI90259
The Journal of Clinical Investigation
Munc13 proteins are essential regulators of neurotransmitter release at nerve cell synapses. They mediate the priming step that renders synaptic vesicles fusion-competent, and their genetic elimination causes a complete block of synaptic transmission
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::19b041988f891359914dc395bd5339bc
https://doi.org/10.1172/jci90259
https://doi.org/10.1172/jci90259
Autor:
Ana Covelo, Alfonso Araque
Publikováno v:
Neuroscience. 323:62-66
Fifteen years ago the concept of the “tripartite synapse” was proposed to conceptualize the functional view that astrocytes are integral elements of synapses. The signaling exchange between astrocytes and neurons within the tripartite synapse res
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3e63e820d3255c11beadf7fc52b36b85
https://doi.org/10.1016/j.neuroscience.2015.02.036
https://doi.org/10.1016/j.neuroscience.2015.02.036
Autor:
Richard Robitaille, Aude Panatier
Publikováno v:
Neuroscience. 323:29-34
In the brain, astrocytes occupy a key position between vessels and synapses. Among their numerous functions, these glial cells are key partners of neurons during synaptic transmission. Astrocytes detect transmitter release through receptors and trans
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::afbb995d4eb5c9cf401d8b54a3d79cf3
https://doi.org/10.1016/j.neuroscience.2015.03.063
https://doi.org/10.1016/j.neuroscience.2015.03.063
3rd International Congress of the Turkish-Neuroendocrinology-Society -- JUN 29-JUL 01, 2018 -- Malatya, TURKEY WOS: 000445952400025 … Turkish Neuroendocrinol Society
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::416442b0e67abb14b7caa5833e934b40
https://hdl.handle.net/20.500.11831/6822
https://hdl.handle.net/20.500.11831/6822
Publikováno v:
Nature neuroscience
Organization of signaling complexes at excitatory synapses by membrane-associated guanylate kinase (MAGUK) proteins regulates synapse development, plasticity, senescence and disease. Post-translational modification of MAGUK family proteins can drive
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f5e1423cb1058e33291f2151b201be86
https://doi.org/10.1038/nn.4140
https://doi.org/10.1038/nn.4140
Publikováno v:
The Journal of General Physiology
A band of microtubules ringing the retinal bipolar cell synaptic terminal may be crucial to supply and anchor the mitochondria required to sustain transmitter release.
A set of bipolar cells in the retina of goldfish contains giant synaptic term
A set of bipolar cells in the retina of goldfish contains giant synaptic term
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ad6836998d587a4e6bfbe9df731c0084
https://doi.org/10.1085/jgp.201511396
https://doi.org/10.1085/jgp.201511396
Publikováno v:
Neuroscience. 291:155-166
The strength of synaptic transmission between a neuron and multiple postsynaptic partners can vary considerably. We have studied synaptic heterogeneity using the glutamatergic Drosophila neuromuscular junction (NMJ), which contains multiple synaptic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3367a05293cddac74c7bbe4fa86bc32e
https://doi.org/10.1016/j.neuroscience.2015.01.069
https://doi.org/10.1016/j.neuroscience.2015.01.069