Zobrazeno 1 - 10
of 1 041
pro vyhledávání: '"Synaptic currents"'
Autor:
Binbin Zhao, Dongfeng Wei, Qinghua Long, Qingjie Chen, Fushun Wang, Linlin Chen, Zefei Li, Tong Li, Tao Ma, Wei Liu, Linshuang Wang, Caishui Yang, Xiaxia Zhang, Ping Wang, Zhanjun Zhang
Publikováno v:
Journal of Pharmaceutical Analysis, Vol 14, Iss 3, Pp 348-370 (2024)
Emerging research suggests a potential association of progression of Alzheimer's disease (AD) with alterations in synaptic currents and mitochondrial dynamics. However, the specific associations between these pathological changes remain unclear. In t
Externí odkaz:
https://doaj.org/article/267654d38bfb4ef2afe0dc07ed609829
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 15 (2022)
Chronic Postsurgical Pain (CPSP) is well recognized to impair cognition, particularly memory. Mounting evidence suggests anatomic and mechanistic overlap between pain and cognition on several levels. Interestingly, the drugs currently used for treati
Externí odkaz:
https://doaj.org/article/280fa59d381946e9b2e5d56a6eb3092f
Autor:
Amira Latif-Hernandez, Victor Sabanov, Tariq Ahmed, Katleen Craessaerts, Takashi Saito, Takaomi Saido, Detlef Balschun
Publikováno v:
Alzheimer’s Research & Therapy, Vol 12, Iss 1, Pp 1-15 (2020)
Abstract Background Intensive basic and preclinical research into Alzheimer’s disease (AD) has yielded important new findings, but they could not yet been translated into effective therapies. One of the reasons is the lack of animal models that suf
Externí odkaz:
https://doaj.org/article/1e4786f2544f436092354c5f169b3626
Autor:
Vincenzo Giacco, Giulia Panattoni, Manuela Medelin, Elena Bonechi, Alessandra Aldinucci, Clara Ballerini, Laura Ballerini
Publikováno v:
Journal of Neuroinflammation, Vol 16, Iss 1, Pp 1-14 (2019)
Abstract Background Synaptic dysfunction, named synaptopathy, due to inflammatory status of the central nervous system (CNS) is a recognized factor potentially underlying both motor and cognitive dysfunctions in neurodegenerative diseases. To gain kn
Externí odkaz:
https://doaj.org/article/09c62134d94d4fa9bd1bea76fbf8fffb
Publikováno v:
Neurobiology of Disease, Vol 152, Iss , Pp 105274- (2021)
It has been reported that hyperexcitability occurs in a subset of patients with Alzheimer's disease (AD) and hyperexcitability could contribute to the disease. Several studies have suggested that the hippocampal dentate gyrus (DG) may be an important
Externí odkaz:
https://doaj.org/article/e8a1aeff944a43e7880a72a9942ba8db
Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.
K zobrazení výsledku je třeba se přihlásit.
Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.
K zobrazení výsledku je třeba se přihlásit.
Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.
K zobrazení výsledku je třeba se přihlásit.
Publikováno v:
Journal of the Royal Statistical Society. Series B (Statistical Methodology), 1999 Jan 01. 61(1), 191-212.
Externí odkaz:
https://www.jstor.org/stable/2680745
Autor:
Antonietta Gentile, Alessandra Musella, Francesca De Vito, Diego Fresegna, Silvia Bullitta, Francesca Romana Rizzo, Diego Centonze, Georgia Mandolesi
Publikováno v:
Journal of Neuroinflammation, Vol 15, Iss 1, Pp 1-13 (2018)
Abstract Background Laquinimod is an immunomodulatory drug under clinical investigation for the treatment of the progressive form of multiple sclerosis (MS) with both anti-inflammatory and neuroprotective effects. Excitotoxicity, a prominent pathophy
Externí odkaz:
https://doaj.org/article/f601bf4bc3d248faaf69f7066fcf3b0b