Zobrazeno 1 - 10
of 204
pro vyhledávání: '"Syma Khalid"'
Autor:
Augustinas Silale, Yiling Zhu, Jerzy Witwinowski, Robert E. Smith, Kahlan E. Newman, Satya P. Bhamidimarri, Arnaud Baslé, Syma Khalid, Christophe Beloin, Simonetta Gribaldo, Bert van den Berg
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-18 (2023)
Abstract The outer membrane (OM) in diderm, or Gram-negative, bacteria must be tethered to peptidoglycan for mechanical stability and to maintain cell morphology. Most diderm phyla from the Terrabacteria group have recently been shown to lack well-ch
Externí odkaz:
https://doaj.org/article/6a9b8496a39b4441b39a450187bae21d
Autor:
Thibaud Dieudonné, Felix Kümmerer, Michelle Juknaviciute Laursen, Charlott Stock, Rasmus Kock Flygaard, Syma Khalid, Guillaume Lenoir, Joseph A. Lyons, Kresten Lindorff-Larsen, Poul Nissen
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-14 (2023)
Abstract Asymmetric distribution of phospholipids in eukaryotic membranes is essential for cell integrity, signaling pathways, and vesicular trafficking. P4-ATPases, also known as flippases, participate in creating and maintaining this asymmetry thro
Externí odkaz:
https://doaj.org/article/aa9dfcfc11924f8586ac72110b5b9aa1
Publikováno v:
QRB Discovery, Vol 5 (2024)
The resistance–nodulation–division efflux machinery confers antimicrobial resistance to Gram-negative bacteria by actively pumping antibiotics out of the cell. The protein complex is powered by proton motive force; however, the proton transfer me
Externí odkaz:
https://doaj.org/article/fdb3c26839df461089698a384a6b0e5a
Autor:
Jan Böhning, Mnar Ghrayeb, Conrado Pedebos, Daniel K. Abbas, Syma Khalid, Liraz Chai, Tanmay A. M. Bharat
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-12 (2022)
Fibres formed by protein TasA are important components of the extracellular matrix in biofilms developed by the bacterium Bacillus subtilis. Here, Böhning et al. use electron cryomicroscopy and other techniques to show how TasA globular monomers ass
Externí odkaz:
https://doaj.org/article/b0538577ebde418a875b0e611cff7203
Autor:
Kahlan E Newman, Syma Khalid
Publikováno v:
PLoS Computational Biology, Vol 19, Iss 1, p e1010841 (2023)
The outer membrane factor CmeC of the efflux machinery CmeABC plays an important role in conferring antibiotic and bile resistance to Campylobacter jejuni. Curiously, the protein is N-glycosylated, with the glycans playing a key role in the effective
Externí odkaz:
https://doaj.org/article/8cdbb75325384a35a8b18a8ec0196015
Autor:
Kahlan E Newman, Sarah N Tindall, Sophie L Mader, Syma Khalid, Gavin H Thomas, Marjan W Van Der Woude
Publikováno v:
eLife, Vol 12 (2023)
Acylation of diverse carbohydrates occurs across all domains of life and can be catalysed by proteins with a membrane bound acyltransferase-3 (AT3) domain (PF01757). In bacteria, these proteins are essential in processes including symbiosis, resistan
Externí odkaz:
https://doaj.org/article/9849aac2dd3d4b87b58d6130bbf696ab
Autor:
Daniel Mann, Junping Fan, Kamolrat Somboon, Daniel P. Farrell, Andrew Muenks, Svetomir B. Tzokov, Frank DiMaio, Syma Khalid, Samuel I. Miller, Julien R. C. Bergeron
Publikováno v:
Communications Biology, Vol 4, Iss 1, Pp 1-9 (2021)
Daniel Mann et al. describe a higher-resolution structure of the maintenance of lipid asymmetry inner membrane complex (MlaBDEF) in the Gram-negative pathogen, Acinetobacter baumannii. With this improved structural map, the authors clarify the second
Externí odkaz:
https://doaj.org/article/85d066ee80af486582adf7e304e0d791
Autor:
Punam Rattu, Flo Glencross, Sophie L. Mader, Chris-Kriton Skylaris, Stephen J. Matthews, Sarah L. Rouse, Syma Khalid
Publikováno v:
Computational and Structural Biotechnology Journal, Vol 19, Iss , Pp 6417-6430 (2021)
Two proteins of the Escherichia coli membrane protein complex, CsgG and CsgF, are studied as proteinaceous nanopores for DNA sequencing. It is highly desirable to control the DNA as it moves through the pores, this requires characterisation of DNA tr
Externí odkaz:
https://doaj.org/article/fd4ef18f4e964d0f82717acf95699cd1
Uptake of monoaromatic hydrocarbons during biodegradation by FadL channel-mediated lateral diffusion
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-13 (2020)
The uptake of hydrophobic molecules by bacterial FadL channels is implicated in quorum sensing, interactions with eukaryotic hosts and biodegradation of many pollutants. Insights into monoaromatic hydrocarbon uptake by TodX and CymD channels suggest
Externí odkaz:
https://doaj.org/article/5cfd1adca51841c49a30a6512bdd70e4
Autor:
Punam Rattu, Flo Glencross, Sophie L. Mader, Chris-Kriton Skylaris, Stephen J. Matthews, Sarah L. Rouse, Syma Khalid
Publikováno v:
Computational and Structural Biotechnology Journal, Vol 20, Iss , Pp 1027- (2022)
Externí odkaz:
https://doaj.org/article/237975da14904d9a883d4d7d50bfed58