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Akademický článek

The Influence of the Mixed DPC:SDS Micelle on the Structure and Oligomerization Process of the Human Cystatin C

Autor: Przemyslaw Jurczak, Emilia Sikorska, Paulina Czaplewska, Sylwia Rodziewicz-Motowidlo, Igor Zhukov, Aneta Szymanska

Publikováno v: Membranes, Vol 11, Iss 1, p 17 (2020)

Human cystatin C (hCC), a member of the superfamily of papain-like cysteine protease inhibitors, is the most widespread cystatin in human body fluids. Physiologically active hCC is a monomer, which dimerization and oligomerization lead to the formati

Externí odkaz: https://doaj.org/article/641739305b824e7bb7e02adb148f26cf

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Prevention of domain swapping inhibits dimerization and amyloid fibril formation of cystatin C: use of engineered disulfide bridges, antibodies, and carboxymethylpapain to stabilize the monomeric form of cystatin C

Autor: Maria, Nilsson, Xin, Wang, Sylwia, Rodziewicz-Motowidlo, Robert, Janowski, Veronica, Lindström, Patrik, Onnerfjord, Gunilla, Westermark, Zbigniew, Grzonka, Mariusz, Jaskolski, Anders, Grubb

Publikováno v: The Journal of biological chemistry. 279(23)

Amyloidogenic proteins like cystatin C and prion proteins have been shown to form dimers by exchange of subdomains of the monomeric proteins. This process, called "three-dimensional domain swapping," has also been suggested to play a part in the gene

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::b1d0ac46d5041c4e71b57ff92c61abbc
https://pubmed.ncbi.nlm.nih.gov/15028721

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Periodical

Medical University of Gdansk Researchers Describe Advances in Tissue Engineering (A novel chitosan-peptide system for cartilage tissue engineering with adipose-derived stromal cells).

Publikováno v: Stem Cell Week; 12/5/2024, p295-295, 1p

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Periodical

Findings from Medical University of Gdansk Broaden Understanding of Melanoma [Targeting BTLA with the peptide inhibitor HVEM(14-39) - A new way to restore the activity of T cells in melanoma].

Publikováno v: Immunotherapy Weekly; 6/11/2024, p775-775, 1p

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Akademický článek

The Influence of the Mixed DPC:SDS Micelle on the Structure and Oligomerization Process of the Human Cystatin C.

Autor: Jurczak, Przemyslaw¹ (AUTHOR) emilia.sikorska@ug.edu.pl, Sikorska, Emilia¹ (AUTHOR) s.rodziewicz-motowidlo@ug.edu.pl, Czaplewska, Paulina² (AUTHOR) paulina.czaplewska@ug.edu.pl, Rodziewicz-Motowidlo, Sylwia¹ (AUTHOR), Zhukov, Igor^3,4 (AUTHOR) przemyslaw.jurczak@ug.edu.pl, Szymanska, Aneta¹ (AUTHOR) przemyslaw.jurczak@ug.edu.pl

Publikováno v: Membranes. Jan2021, Vol. 11 Issue 1, p17. 1p.

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