The prion protein M129V polymorphism

Autor: Pawel P. Liberski, Elizabeth H. Corder, Maria Barcikowska, Sylwia M. Gresner, Ewa Golanska, Anna Pfeffer, Małgorzata Mossakowska, Tomasz Sobów, Aleksandra Szybinska, Monika Sieruta, Izabela Klich, Malgorzata Chodakowska-Zebrowska

Publikováno v: Prion. 7:244-247

The PRNP gene encodes the cellular isoform of prion protein (PrP (c) ). The M129V polymorphism influences the risk of prion diseases and may modulate the rate of neurodegeneration with age. We present the first study of the polymorphism among Polish

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bb90b85eaddb42f8e9a2e0bd135b1249
https://doi.org/10.4161/pri.23903

Polycomb genes expression as a predictor of poor clinical outcome in children with medulloblastoma

Autor: Krzysztof Zakrzewski, Magdalena Zakrzewska, Beata Zalewska-Szewczyk, Sylwia M. Gresner, Sylwester Piaskowski, Pawel P. Liberski

Publikováno v: Child's Nervous System

Introduction Medulloblastoma is the most frequent type of embryonal tumor in the pediatric population, accounting for 20–25% of all brain tumors in children. Recently, the suspected contribution of the Polycomb group (PcG) genes in medulloblastoma

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::346e7c51200f61c0b8b55f4778d89062
http://europepmc.org/articles/PMC3015167

Neuronal and astrocytic cells, obtained after differentiation of human neural GFAP-positive progenitors, present heterogeneous expression of PrPc

Autor: Piotr Rieske, Barbara Krynska, Paul Brown, S. Ausim Azizi, Monika Witusik, Sylwia M. Gresner, Pawel P. Liberski, Krystyna Hulas-Bigoszewska

Publikováno v: Brain Research. 1186:65-73

PrP(c) is a cellular isoform of the prion protein with an unknown normal function. One of the putative physiological roles of this protein is its involvement in cell differentiation. Recently, in vitro and in vivo studies showed that GFAP-positive ce

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::53434578abbf4f7326e7a827de088416
https://doi.org/10.1016/j.brainres.2007.10.039

Novel gene expression model for outcome prediction in paediatric medulloblastoma

Autor: Krzysztof Zakrzewski, Magdalena Zakrzewska, Sylwia M. Gresner, Beata Zalewska-Szewczyk, Pawel P. Liberski

Publikováno v: Journal of molecular neuroscience : MN. 51(2)

Medulloblastoma is the most frequent type of embryonal tumour in the paediatric population. The disease progression in patients with this tumour may be connected with the presence of stem/tumour-initiating cells, but the precise source and characteri

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::01a32dc3621198d97f70bec410dc414b
https://pubmed.ncbi.nlm.nih.gov/23649504

Glioblastoma-derived spheroid cultures as an experimental model for analysis of EGFR anomalies

Autor: Ewelina Stoczynska-Fidelus, Sylwester Piaskowski, James W. Ironside, Sylwia M. Gresner, Dominika Kulczycka-Wojdala, Pawel P. Liberski, Michał Bieńkowski, Wielisław Papierz, Krystyna Hulas-Bigoszewska, Piotr Rieske, Krzysztof Zakrzewski, Magdalena Zakrzewska, Maciej Kolasa, Monika Witusik-Perkowska, Robert Stawski, Dariusz J. Jaskólski

Publikováno v: Witusik-Perkowska, M, Rieske, P, Hulas-Bigoszewska, K, Zakrzewska, M, Stawski, R, Kulczycka-Wojdala, D, Bienkowski, M, Stoczynska-Fidelus, E, Gresner, S M, Piaskowski, S, Jaskolski, D J, Papierz, W, Zakrzewski, K, Kolasa, M, Ironside, J W & Liberski, P P 2011, ' Glioblastoma-derived spheroid cultures as an experimental model for analysis of EGFR anomalies ', Journal of Neuro-Oncology, vol. 102, no. 3, pp. 395-407 . https://doi.org/10.1007/s11060-010-0352-0
Journal of Neuro-Oncology

Glioblastoma cell cultures in vitro are frequently used for investigations on the biology of tumors or new therapeutic approaches. Recent reports have emphasized the importance of cell culture type for maintenance of tumor original features. Neverthe

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d5449f7b7f38fd5712fb09d17d9ce2c2
https://www.pure.ed.ac.uk/ws/files/8535381/Glioblastoma_derived_spheroid_cultures_as_an_experimental_model_for_analysis_of_EGFR_anomalies.pdf