Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Sylwia Król"'
Autor:
Sylwia Król, Nicklas Österlund, Faraz Vosough, Jüri Jarvet, Sebastian Wärmländer, Andreas Barth, Leopold L. Ilag, Mazin Magzoub, Astrid Gräslund, Cecilia Mörman
Publikováno v:
iScience, Vol 26, Iss 4, Pp 106576- (2023)
Externí odkaz:
https://doaj.org/article/2eb4a04c8bd24ddb81b608cb993a6a93
Autor:
Lucía Gallego-Villarejo, Cecilia Wallin, Sylwia Król, Jennifer Enrich-Bengoa, Albert Suades, Marcel Aguilella-Arzo, María José Gomara, Isabel Haro, Sebastian Wärmlander, Francisco J. Muñoz, Astrid Gräslund, Alex Perálvarez-Marín
Publikováno v:
Computational and Structural Biotechnology Journal, Vol 20, Iss , Pp 5672-5679 (2022)
Amyloid β-peptide (Aβ) misfolding into β-sheet structures triggers neurotoxicity inducing Alzheimer’s disease (AD). Molecules able to reduce or to impair Aβ aggregation are highly relevant as possible AD treatments since they should protect aga
Externí odkaz:
https://doaj.org/article/41f9e8a18a724612a8ff51043ed9619a
Autor:
David J Yanofsky, Justin M Di Trani, Sylwia Król, Rana Abdelaziz, Stephanie A Bueler, Peter Imming, Peter Brzezinski, John L Rubinstein
Publikováno v:
eLife, Vol 10 (2021)
The imidazopyridine telacebec, also known as Q203, is one of only a few new classes of compounds in more than 50 years with demonstrated antituberculosis activity in humans. Telacebec inhibits the mycobacterial respiratory supercomplex composed of co
Externí odkaz:
https://doaj.org/article/1d6aa07f32734bd39aa34dc44cea219b
Autor:
Sylwia Król, Nicklas Österlund, Faraz Vosough, Jüri Jarvet, Sebastian Wärmländer, Andreas Barth, Leopold L. Ilag, Mazin Magzoub, Astrid Gräslund, Cecilia Mörman
Publikováno v:
iScience, Vol 24, Iss 8, Pp 102852- (2021)
Summary: Substantial research efforts have gone into elucidating the role of protein misfolding and self-assembly in the onset and progression of Alzheimer’s disease (AD). Aggregation of the Amyloid-β (Aβ) peptide into insoluble fibrils is closel
Externí odkaz:
https://doaj.org/article/d74b1b8349294068ae186acea6f04255
Autor:
Anja Henning-Knechtel, Sunil Kumar, Cecilia Wallin, Sylwia Król, Sebastian K.T.S. Wärmländer, Jüri Jarvet, Gennaro Esposito, Serdal Kirmizialtin, Astrid Gräslund, Andrew D. Hamilton, Mazin Magzoub
Publikováno v:
Cell Reports Physical Science, Vol 1, Iss 2, Pp 100014- (2020)
Summary: Amyloid proteins and peptides are a major contributing factor to the development of various neurodegenerative disorders, including Alzheimer’s and prion diseases. Previously, a designed cell-penetrating peptide (CPP) comprising a hydrophob
Externí odkaz:
https://doaj.org/article/5d236af9e01344af9941d4946465ac90
Autor:
Faraz Vosough, Cecilia Mörman, Nicklas Österlund, Leopold L. Ilag, Sebastian K.T.S. Wärmländer, Sylwia Król, Andreas Barth, Astrid Gräslund, Jüri Jarvet, Mazin Magzoub
Publikováno v:
iScience
iScience, Vol 24, Iss 8, Pp 102852-(2021)
iScience, Vol 24, Iss 8, Pp 102852-(2021)
Summary Substantial research efforts have gone into elucidating the role of protein misfolding and self-assembly in the onset and progression of Alzheimer’s disease (AD). Aggregation of the Amyloid-β (Aβ) peptide into insoluble fibrils is closely
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::914fbf3c3aaef563e7e82f4fc2bab451
https://europepmc.org/articles/PMC10119786/
https://europepmc.org/articles/PMC10119786/
Publikováno v:
Biochimica et biophysica acta. Bioenergetics. 1863(7)
The M. smegmatis respiratory III
Autor:
Sylwia Król, Rana Abdelaziz, John L. Rubinstein, Stephanie A. Bueler, Peter Brzezinski, David J. Yanofsky, Justin M. Di Trani, Peter Imming
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1bdd4553845187e47ed01caa66326b35
https://doi.org/10.7554/elife.71959.sa2
https://doi.org/10.7554/elife.71959.sa2
Autor:
Peter Brzezinski, Sylwia Król, John L. Rubinstein, David J. Yanofsky, Peter Imming, Justin M. Di Trani, Rana Abdelaziz, Stephanie A. Bueler
Publikováno v:
eLife, Vol 10 (2021)
The imidazopyridine telacebec, also known as Q203, is one of only a few new classes of compounds in more than 50 years with demonstrated antituberculosis activity in humans. Telacebec inhibits the mycobacterial respiratory supercomplex composed of co
Autor:
Sylwia Król, Peter Brzezinski, David J. Yanofsky, Justin M. Di Trani, Stephanie A. Bueler, John L. Rubinstein, Peter Imming, Rana Abdelaziz
The imidazopyridine telacebec, also known as Q203, is one of only a few new classes of compounds in more than fifty years with demonstrated antituberculosis activity in humans. Telacebec inhibits the mycobacterial respiratory supercomplex composed of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a6a8f7cdbb8b552de718889c58801210
https://doi.org/10.1101/2021.07.06.451285
https://doi.org/10.1101/2021.07.06.451285