Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Sylwia Chelstowska"'
Autor:
Ali Vaziri-Gohar, Jonathan J. Hue, Ata Abbas, Hallie J. Graor, Omid Hajihassani, Mehrdad Zarei, George Titomihelakis, John Feczko, Moeez Rathore, Sylwia Chelstowska, Alexander W. Loftus, Rui Wang, Mahsa Zarei, Maryam Goudarzi, Renliang Zhang, Belinda Willard, Li Zhang, Adam Kresak, Joseph E. Willis, Gi-Ming Wang, Curtis Tatsuoka, Joseph M. Salvino, Ilya Bederman, Henri Brunengraber, Costas A. Lyssiotis, Jonathan R. Brody, Jordan M. Winter
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-13 (2023)
Abstract Pancreatic Ductal Adenocarcinoma (PDAC) is highly resistant to chemotherapy. Effective alternative therapies have yet to emerge, as chemotherapy remains the best available systemic treatment. However, the discovery of safe and available adju
Externí odkaz:
https://doaj.org/article/d2faef86ea85483498c70286f6d2ac00
Autor:
Jason M. Arne, Made Airanthi K. Widjaja-Adhi, Taylor Hughes, Kevin W. Huynh, Josie A. Silvaroli, Sylwia Chelstowska, Vera Y. Moiseenkova-Bell, Marcin Golczak
Publikováno v:
Journal of Lipid Research, Vol 58, Iss 4, Pp 719-730 (2017)
The esterification of alcohols with fatty acids is a universal mechanism to form inert storage forms of sterols, di- and triacylglycerols, and retinoids. In ocular tissues, formation of retinyl esters is an essential step in the enzymatic regeneratio
Externí odkaz:
https://doaj.org/article/83fd6e21e1de493c8405571a696ea69c
Autor:
Thomas Trischman, Marcin Golczak, Josie A. Silvaroli, Sylwia Chelstowska, Ilya Bederman, Made Airanthi K. Widjaja-Adhi, Rony R. Sayegh
Publikováno v:
FASEB J
Lipids secreted by the meibomian glands (MGs) of the eyelids are essential to the protection of the eye’s surface. An altered meibum composition represents the primary cause of evaporative dry eye disease (DED). Despite the critical importance of t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::72ef36dacca57b5d7b96120e438e8083
https://doi.org/10.1096/fj.202001191r
https://doi.org/10.1096/fj.202001191r
Autor:
Piotr Socha, Elizabeth Shumbayawonda, Abhishek Roy, Caitlin Langford, Paul Aljabar, Malgorzata Wozniak, Sylwia Chełstowska, Elzbieta Jurkiewicz, Rajarshi Banerjee, Ken Fleming, Maciej Pronicki, Kamil Janowski, Wieslawa Grajkowska
Publikováno v:
Journal of Pathology Informatics, Vol 15, Iss , Pp 100372- (2024)
Background: Chronic liver disease diagnoses depend on liver biopsy histopathological assessment. However, due to the limitations associated with biopsy, there is growing interest in the use of quantitative digital pathology to support pathologists. W
Externí odkaz:
https://doaj.org/article/2b86709eac224c63bd682dda77183019
Autor:
Jakub Nalepa, Szymon Adamski, Krzysztof Kotowski, Sylwia Chelstowska, Magdalena Machnikowska-Sokolowska, Oskar Bozek, Agata Wisz, Elzbieta Jurkiewicz
Publikováno v:
Computers in Biology and Medicine. 142:105237
Optic pathway gliomas are low-grade neoplastic lesions that account for approximately 3-5% of brain tumors in children. Assessing tumor burden from magnetic resonance imaging (MRI) plays a central role in its efficient management, yet it is a challen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fe93447faef4900d077bc0eb6c1f4f0e
https://doi.org/10.1016/j.compbiomed.2022.105237
https://doi.org/10.1016/j.compbiomed.2022.105237
Publikováno v:
Biochemistry. 56:4489-4499
Vitamin A (all-trans-retinol) is metabolized to the visual chromophore (11-cis-retinal) in the eyes and to all-trans-retinoic acid, a hormone like compound, in most tissues. A key enzyme in retinoid metabolism is lecithin:retinol acyltransferase (LRA
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c391b8a423d61b22deb79f9cc355680f
https://doi.org/10.1021/acs.biochem.7b00451
https://doi.org/10.1021/acs.biochem.7b00451
Autor:
Josie A. Silvaroli, Made Airanthi K. Widjaja-Adhi, Philip D. Kiser, Samantha M. Horwitz, Surajit Banerjee, William S. Blaner, Sylwia Chelstowska, Thomas Trischman, Marcin Golczak
Publikováno v:
ACS chemical biology. 14(3)
Cellular retinol-binding proteins (CRBPs) facilitate the uptake and intracellular transport of vitamin A. They integrate retinoid metabolism, playing an important role in regulating the synthesis of bioactive vitamin A metabolites. Thus, CRBPs consti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aec4ee93906ec86a998d7837fc2dec8f
https://pubmed.ncbi.nlm.nih.gov/30721022
https://pubmed.ncbi.nlm.nih.gov/30721022
Autor:
Sylwia Chelstowska, Taylor E. T. Hughes, Kevin W. Huynh, Marcin Golczak, Josie A. Silvaroli, Vera Y. Moiseenkova-Bell, Made Airanthi K. Widjaja-Adhi, Jason M. Arne
Publikováno v:
Journal of Lipid Research, Vol 58, Iss 4, Pp 719-730 (2017)
The esterification of alcohols with fatty acids is a universal mechanism to form inert storage forms of sterols, di- and triacylglycerols, and retinoids. In ocular tissues, formation of retinyl esters is an essential step in the enzymatic regeneratio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b9f912cb3855afd19eeeda7b8a52c7cc
https://europepmc.org/articles/PMC5392747/
https://europepmc.org/articles/PMC5392747/
Publikováno v:
Lung
Objectives We conducted a study on usefulness of the tuberculin skin test (TST) and the Quantiferon-TB Gold IT (QFT) tests as predictors of radiological changes after contact with tuberculosis. Materials and Methods The study group consisted of TB-ex
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::50525f6f30cfa176fd96a9745eeb9688
https://doi.org/10.1007/s00408-014-9637-y
https://doi.org/10.1007/s00408-014-9637-y
Publikováno v:
Scopus-Elsevier
Europe PubMed Central
Europe PubMed Central
Introduction For many years, Poland has had a mandatory vaccination program against tuberculosis, which recommended repeated vaccinations from birth to adulthood. Therefore, the clinical value of the tuberculin skin test (TST) in diagnosing latent tu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0232ed71329227cc6e9d2e8f6a4712d4
https://doi.org/10.20452/pamw.2075
https://doi.org/10.20452/pamw.2075