Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Sylwia, Olejniczak"'
Autor:
Robert Koralewski, Michał Kowalski, Krzysztof Matyszewski, Sylwia Olejniczak, Piotr L. Sklepkiewicz, Michal Piotrowicz, Czestkowski Wojciech J, Michal Mlacki, Adam Golebiowski, Karolina Dzwonek, Barbara Dymek, Magdalena Salamon, Bartlomiej Borek, Piotr Niedziejko, Agnieszka Bartoszewicz, Marcin Nowotny, Agnieszka Zagozdzon, Mariusz Gruza, Agnieszka Napiorkowska-Gromadzka, Aneta Bartlomiejczak, Pawel Dobrzanski, Marzena Mazur, Gleb Andryianau, Magdalena Kania, Jakub Golab, Pluta Elzbieta, Karol Jedrzejczak, Witold Mozga, Marcin Mazurkiewicz, Tomasz Rejczak, Jacek Olczak, Sylwia Piasecka, Aleksandra Rymaszewska
Publikováno v:
Journal of Medicinal Chemistry. 63:15527-15540
Chitotriosidase (CHIT1) and acidic mammalian chitinase (AMCase) are the enzymatically active chitinases that have been implicated in the pathology of chronic lung diseases such as asthma and inters...
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a2dd9844a8fb40d1518481d781cdfd6d
https://doi.org/10.1021/acs.jmedchem.0c01179
https://doi.org/10.1021/acs.jmedchem.0c01179
Autor:
Robert, Koralewski, Barbara, Dymek, Marzena, Mazur, Piotr, Sklepkiewicz, Sylwia, Olejniczak, Wojciech, Czestkowski, Krzysztof, Matyszewski, Gleb, Andryianau, Piotr, Niedziejko, Michal, Kowalski, Mariusz, Gruza, Bartłomiej, Borek, Karol, Jedrzejczak, Agnieszka, Bartoszewicz, Elżbieta, Pluta, Aleksandra, Rymaszewska, Magdalena, Kania, Tomasz, Rejczak, Sylwia, Piasecka, Michal, Mlacki, Marcin, Mazurkiewicz, Michał, Piotrowicz, Magdalena, Salamon, Agnieszka, Zagozdzon, Agnieszka, Napiorkowska-Gromadzka, Aneta, Bartlomiejczak, Witold, Mozga, Paweł, Dobrzański, Karolina, Dzwonek, Jakub, Golab, Marcin, Nowotny, Jacek, Olczak, Adam, Golebiowski
Publikováno v:
Journal of medicinal chemistry. 63(24)
Chitotriosidase (CHIT1) and acidic mammalian chitinase (AMCase) are the enzymatically active chitinases that have been implicated in the pathology of chronic lung diseases such as asthma and interstitial lung diseases (ILDs), including idiopathic pul
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::b9418f8d294ee157abcdfd2a01099fe4
https://pubmed.ncbi.nlm.nih.gov/33078933
https://pubmed.ncbi.nlm.nih.gov/33078933
Autor:
Sylwia Olejniczak, Anna Mietelska-Porowska, Urszula Wojda, Jakub Golab, Katarzyna Laskowska-Kaszub, Stanislaw Pikul, Mykola Zdioruk, Andrew Want, Agata Klejman, Paulina Koza, Joanna Wojsiat, Witold Konopka, Ewelina Użarowska
Publikováno v:
Cancers
Volume 12
Issue 8
Cancers, Vol 12, Iss 2161, p 2161 (2020)
Volume 12
Issue 8
Cancers, Vol 12, Iss 2161, p 2161 (2020)
Induction of mitotic catastrophe through the disruption of microtubules is an established target in cancer therapy. However, the molecular mechanisms determining the mitotic catastrophe and the following apoptotic or non-apoptotic cell death remain p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::772adcc671c9d9cd7bfcfd639041b2d1
Autor:
Robert Koralewski, Gleb Andryianau, Krzysztof Matyszewski, Bartlomiej Borek, Pluta Elzbieta, Adam Golebiowski, Marcin Mazurkiewicz, Jakub Golab, Barbara Dymek, Piotr Niedziejko, Czestkowski Wojciech J, Michal Piotrowicz, Michał Kowalski, Sylwia Olejniczak, Marzena Mazur, Jacek Olczak, Agnieszka Zagozdzon, Filip Stefaniak, Karolina Dzwonek, Agnieszka Bartoszewicz, Mariusz Gruza, Magdalena Salamon
Publikováno v:
Bioorganic & Medicinal Chemistry Letters
This article describes our work towards the identification of a potent and selective inhibitor of mouse chitotriosidase (mCHIT1). A series of small molecule inhibitors of mCHIT1 and mAMCase have been developed from early lead compound 1 . Examination
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::340f6f7ae7b7c75d35d3b35d53144a21
https://doi.org/10.1016/j.bmcl.2017.12.047
https://doi.org/10.1016/j.bmcl.2017.12.047
Autor:
Agnieszka Bartoszewicz, Aleksandra Rymaszewska, Agnieszka Zagozdzon, Jakub Golab, Pawel Dobrzanski, Marcin Mazurkiewicz, Filip Stefaniak, Czestkowski Wojciech J, Adam Golebiowski, Bartlomiej Borek, Karolina Dzwonek, Robert Koralewski, Piotr L. Sklepkiewicz, Krzysztof Matyszewski, Barbara Dymek, Sylwia Olejniczak, Marzena Mazur, Michał Piotrowicz, Magdalena Salamon, Jacek Olczak, Pluta Elzbieta, Karol Jedrzejczak, Witold Mozga
Publikováno v:
Journal of medicinal chemistry. 62(15)
Acidic mammalian chitinase (AMCase) and chitotriosidase-1 (CHIT1) are two enzymatically active proteins produced by mammals capable of cleaving the glycosidic bond in chitin. Based on the clinical findings and animal model studies, involvement of chi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7391f2edfc78a24c715b46724e5643ef
https://pubmed.ncbi.nlm.nih.gov/31291098
https://pubmed.ncbi.nlm.nih.gov/31291098
Autor:
Piotr L. Sklepkiewicz, Czestkowski Wojciech J, Bruce R. Conway, Ryan Sheeler, Tom Noonan, Alexandra Cousido-Siah, Alberto Podjarny, Sylwia Olejniczak, Agnieszka Zagozdzon, Jacek Olczak, Anna Jedrzejczak, Andre Mitschler, Adam Golebiowski, Paul Beckett, Firas Fadel, Karolina Dzwonek, Marzena Mazur, William M. Hungerford, Barbara Dymek, Robert Koralewski, Jakub Golab, Keyvan Mahboubi
Publikováno v:
Journal of Medicinal Chemistry
This article highlights our work toward the identification of a potent, selective, and efficacious acidic mammalian chitinase (AMCase) inhibitor. Rational design, guided by X-ray analysis of several inhibitors bound to human chitotriosidase (hCHIT1),
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::20e71f10924a2a26218929e3bfde2f2d
https://pubmed.ncbi.nlm.nih.gov/29283260
https://pubmed.ncbi.nlm.nih.gov/29283260