Výsledky vyhledávání - "Sylwia, Machcinska"

Akademický článek

Hypoxia and Foxn1 alter the proteomic signature of dermal fibroblasts to redirect scarless wound healing to scar-forming skin wound healing in Foxn1−/− mice

Autor: Barbara Gawronska-Kozak, Sylwia Machcinska-Zielinska, Katarzyna Walendzik, Marta Kopcewicz, Mirva Pääkkönen, Joanna Wisniewska

Publikováno v: BMC Biology, Vol 22, Iss 1, Pp 1-28 (2024)

Abstract Background Foxn1−/− deficient mice are a rare model of regenerative skin wound healing among mammals. In wounded skin, the transcription factor Foxn1 interacting with hypoxia-regulated factors affects re-epithelialization, epithelial-mes

Externí odkaz: https://doaj.org/article/33328056436a41b5b95c0bf8d1f7c447

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Akademický článek

Gender Differences in Post-Operative Human Skin

Autor: Barbara Gawronska-Kozak, Marta Kopcewicz, Sylwia Machcinska-Zielinska, Katarzyna Walendzik, Joanna Wisniewska, Justyna Drukała, Tomasz Wasniewski, Joanna Rutkowska, Piotr Malinowski, Michał Pulinski

Publikováno v: Biomedicines, Vol 11, Iss 10, p 2653 (2023)

Although the impact of age, gender, and obesity on the skin wound healing process has been extensively studied, the data related to gender differences in aspects of skin scarring are limited. The present study performed on abdominal human intact and

Externí odkaz: https://doaj.org/article/0939ece4a8ac4cdaa77a479ec9939132

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Histology Scoring System for Murine Cutaneous Wounds

Autor: Mari van de Vyver, Johanna Nunez, Michelle Maartens, Emma Rogers, Trivia Frazier, Sylwia Machcinska, Kiara Boodhoo, Katie Hamel, Benjamin Levi, Chase A. Pagani, Barbara Gawronska-Kozak, Katarzyna Walendzik, Joanna Wisniewska, Marta Kopcewicz, Jeffrey M. Gimble

Publikováno v: Stem Cells Dev

Monitoring wound progression over time is a critical aspect for studies focused on in-depth molecular analysis or on evaluating the efficacy of potential novel therapies. Histopathological analysis of wound biopsies can provide significant insight in

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f9a87c81f1f9ce380fde494b1d760a99
https://doi.org/10.1089/scd.2021.0124

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Hypoxia reveals a new function of Foxn1 in the keratinocyte antioxidant defense system

Autor: Sylwia Machcinska, Katarzyna Walendzik, Marta Kopcewicz, Joanna Wisniewska, Anne Rokka, Mirva Pääkkönen, Mariola Slowinska, Barbara Gawronska‐Kozak

Publikováno v: The FASEB Journal. 36

Skin exposed to environmental threats, including injuries and oxidative stress, develops an efficient but not fully recognized system of repair and antioxidant protection. Here, using mass spectrometry analysis (LC-MS/MS), followed by in vitro and in

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b2a01060cc4ed235b1ecc3dd5272b613
https://doi.org/10.1096/fj.202200249rr

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Adipose-Derived Stromal/Stem Cells from Large Animal Models: from Basic to Applied Science

Autor: Sylwia Machcinska, Katarzyna Walendzik, Anna Szóstek-Mioduchowska, Marta Kopcewicz, Joanna Bukowska, Barbara Gawronska-Kozak

Publikováno v: Stem Cell Reviews and Reports

Adipose-derived stem cells (ASCs) isolated from domestic animals fulfill the qualitative criteria of mesenchymal stem cells, including the capacity to differentiate along multiple lineage pathways and to self-renew, as well as immunomodulatory capaci

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::44ca03f541f565893d4b28651de52bc6
https://doi.org/10.1007/s12015-020-10049-y

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Dermal White Adipose Tissue (dWAT) Is Regulated by Foxn1 and Hif-1α during the Early Phase of Skin Wound Healing

Autor: Barbara Gawronska-Kozak, Katarzyna Walendzik, Sylwia Machcinska, Artur Padzik, Marta Kopcewicz, Joanna Wiśniewska

Publikováno v: International Journal of Molecular Sciences
International Journal of Molecular Sciences; Volume 23; Issue 1; Pages: 257
International Journal of Molecular Sciences, Vol 23, Iss 257, p 257 (2022)

Dermal white adipose tissue (dWAT) is involved in the maintenance of skin homeostasis. However, the studies concerning its molecular regulation are limited. In the present paper, we ask whether the introduction of two transcription factors, Foxn1 and

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::82377de66da261ba37b9d469a86c7968
http://europepmc.org/articles/PMC8745105

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Age, Diet and Epidermal Signaling Modulate Dermal Fibroblasts' Adipogenic Potential

Autor: Barbara Gawronska-Kozak, Joanna Bukowska, Marta Kopcewicz, Jeffrey M. Gimble, Sylwia Machcinska, Katarzyna Walendzik

Publikováno v: International Journal of Molecular Sciences
Volume 21
Issue 23

The recognition of a distinct fat depot, the dermal white adipose tissue (dWAT), points out the complexity of the interaction among skin resident cells: keratinocytes, dermal fibroblasts (DFs) and adipocytes in response to physiological (diet, age) a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::04f3c6de56c381e2b1fdad063a8323a6
https://pubmed.ncbi.nlm.nih.gov/33255750

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Impairment of the Hif-1α regulatory pathway in Foxn1-deficient (Foxn1

Autor: Sylwia, Machcinska, Marta, Kopcewicz, Joanna, Bukowska, Katarzyna, Walendzik, Barbara, Gawronska-Kozak

Publikováno v: FASEB journal : official publication of the Federation of American Societies for Experimental BiologyREFERENCES. 35(2)

Hypoxia and hypoxia-regulated factors (eg, hypoxia-inducible factor-1α [Hif-1α], factor inhibiting Hif-1α [Fih-1], thioredoxin-1 [Trx-1], aryl hydrocarbon receptor nuclear translocator 2 [Arnt-2]) have essential roles in skin wound healing. Using

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::205d0f6f7946f676de0c3e44d4acf493
https://pubmed.ncbi.nlm.nih.gov/33475195

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