Výsledky vyhledávání - "Sylvie Tymciu"

Validation of iQ-Check E. coli O157:H7 Real-Time PCR Test Kit for Detection of Escherichia coli O157:H7 in Selected Foods

Autor: Wendy F Lauer, Pierre Sonigo, Sylvie Tymciu, Caroline D Sidi

Publikováno v: Journal of AOAC INTERNATIONAL. 92:1095-1104

iQ-Check E. coli O157:H7 (Bio-Rad Laboratories, Hercules, CA) is a real-time PCR kit for detection of E. coli O157:H7 from selected foods. Specific fluorescent oligonucleotide probes are used to detect target DNA during the amplification, by hybridiz

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::9b99f95354c81125cc6541a6259159d9
https://doi.org/10.1093/jaoac/92.4.1095

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Radiosynthesis and ex vivo evaluation of [11C]-SIB-1553A as a PET radiotracer for β4 selective subtype nicotinic acetylcholine receptor

Autor: Martine Dhilly, Danièle Debruyne, Louisa Barré, Thomas Bourdier, Franck Sobrio, Sylvie Tymciu, Thomas Quentin

Publikováno v: Nuclear Medicine and Biology. 35:377-385

[11C]-SIB-1553A ((+/-)-4-[2-((N-[11C]-methyl)-2-pyrrolidinyl)ethyl]thiophenol) was labelled with carbon-11 (t1/2=20.4 min) and evaluated in vivo as potential radiotracer for noninvasive assessment of the beta4 subunit nicotinic acetylcholine neurotra

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::982bdb98b63f4273a8332d5582609358
https://doi.org/10.1016/j.nucmedbio.2007.11.011

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Synthesis and biological evaluation of novel fluoro and iodo quinoline carboxamides as potential ligands of NK-3 receptors for in vivo imaging studies

Autor: Louisa Barré, Marie-Claire Lasne, Martine Dhilly, Idriss Bennacef, Cécile Perrio, Sylvie Tymciu, Danielle Debruyne

Publikováno v: Bioorganic & Medicinal Chemistry. 12:4533-4541

In order to develop radioligands of human NK-3 receptor (hNK-3r) for imaging studies by positron emission tomography (PET) or single photon emission computed tomography (SPECT), a new series of fluoro- and iodo-quinoline carboxamides were synthesized

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1551adae168287f2a52af87708aebfca
https://doi.org/10.1016/j.bmc.2004.05.020

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Enhancement of Antibody Responses in DNA Vaccination Using a Vector Encoding a Universal T-Helper Cell Epitope

Autor: Sylvie Tymciu, Anne Wijkhuisen, Coralie Durieux-Alexandrenne, Jean-Yves Couraud, Yveline Frobert, Christophe Créminon, Didier Boquet, Jacques Grassi

Publikováno v: DNA and Cell Biology. 23:395-402

DNA vaccination appears as a very promising approach to raise protective antibodies against a variety of proteins from pathogens or tumor cells, but is often hindered by the low immunogenicity of the genetic vectors used for the immunizations. To enh

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e1f1fab17cc13696f472e2c2b890a35c
https://doi.org/10.1089/104454904323145281

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Lithiation of Functionalized Fluoroquinolines: Synthesis of Dihalo-2-phenylquinoline-4-carboxamides and in Vitro Evaluation as NK-3 Receptor Ligands for Medical Imaging Studies

Autor: Louisa Barré, Sylvie Tymciu, Cécile Perrio, Florence Mongin, Marie‐Claire Lasne, Idriss Bennacef, Martine Dhilly, Guy Quéguiner

Publikováno v: The Journal of Organic Chemistry. 69:2622-2625

Fluoroiodo-2-phenylquinoline-4-carboxamides, analogues of NK-3 antagonist SB 223412, were synthesized and evaluated as NK-3 ligands with the aim of developing radioligands suitable for both Positron Emission Tomography (PET) and Single Photon Emissio

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::75e9babd34fde58aa85a1c6b6ecb5c4a
https://doi.org/10.1021/jo0358426

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Validation of iQ-Check E. coli O157:H7 real-time PCR test kit for detection of Escherichia coli O157:H7 in selected foods

Autor: Wendy F, Lauer, Sylvie, Tymciu, Caroline D, Sidi, Pierre, Sonigo

Publikováno v: Journal of AOAC International. 92(4)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::a619969fab37406b70d69c8c808bb1ee
https://pubmed.ncbi.nlm.nih.gov/19714978

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Synthesis and biological evaluation of halogenated naphthyridone carboxamides as potential ligands for in vivo imaging studies of substance P receptors

Autor: Anne Wijkhuisen, Marie Claire Lasne, † Caroline Bagot-Guéret, Louisa Barré,† and, Cécile Perrio, Patrick Emond, Mircea Darabantu, Marie-Delphine Le Bas, Sylvie Tymciu, Denis Guilloteau

Publikováno v: Bioconjugate chemistry. 14(3)

With the aim of developing new radioligands for in vivo studies of substance P receptors using positron emission tomography or single photon emission computed tomography, 2- and 3-halo naphthyridone-6-carboxamide derivatives were synthesized. Their a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c38dbc2235d22b8d1bb4e62277aea98e
https://pubmed.ncbi.nlm.nih.gov/12757389

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Pharmacological properties of peptides derived from an antibody against the tachykinin NK(1) receptor for the neuropeptide substance P

Autor: Sylvie Tymciu, Christophe Créminon, Jean-Yves Couraud, Yveline Frobert, Coralie Alexandrenne, Anne Wijkhuisen, M. Conrath, J. Fischer, Didier Boquet, Jacques Grassi

Publikováno v: European Journal of Pharmacology
European Journal of Pharmacology, Elsevier, 2003, 468 (3), pp.175-182
European Journal of Pharmacology, 2003, 468 (3), pp.175-182

Two peptides were derived from the structural analysis of a previously described monoclonal antibody [Mol. Immunol. 37 (2000) 423] against the tachykinin NK 1 receptor for the neuropeptide substance P. Here we show that these two peptides were able t

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::29b398efd028cdbeb45c167ddc646516
https://hal.archives-ouvertes.fr/hal-00109876

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