Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Sylvie Thirot"'
Publikováno v:
ResearcherID
Methylation reactions occurring between trimethyl orthocarboxylates or N,N-dimethylcarboxamide dimethyl acetals and various hydroxylated heterocycles, involving a lactam-lactim tautomeric equilibrium, were investigated as an alternative to classic me
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::360ab2b1da82325a66bb09bec430b167
https://doi.org/10.1002/1099-0690(200206)2002:11<1763::aid-ejoc1763>3.0.co
https://doi.org/10.1002/1099-0690(200206)2002:11<1763::aid-ejoc1763>3.0.co
Autor:
Dominique Hourdet, Sylvie Thirot, Valessa Barbier, Jan Sudor, Michelle Millequant, Jean-Louis Viovy, Dominique Godfrin, Julien Blanchard
Publikováno v:
ELECTROPHORESIS. 22:720-728
A new family of matrices for DNA sequencing by capillary electrophoresis is presented. These matrices combine easy injection with high sieving performances, due to thermal switching between a low and a high viscosity state through a modest increase i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bda0d838e0be88f857abd0ac7e5ae07c
https://doi.org/10.1002/1522-2683(200102)22:4<720::aid-elps720>3.0.co
https://doi.org/10.1002/1522-2683(200102)22:4<720::aid-elps720>3.0.co
Publikováno v:
Tetrahedron. 52:10427-10440
Whereas thermal cyclisation of variously substituted 2,3-diarylacrylazides easily provided a new way to 3-aryl-isoquinolones, nitration of these compounds mainly led to corresponding 3-aryl-4-nitro-isoquinolones. After reduction into 4-amino-3-aryl-i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::944e6fc4e3bd0ab0236f2d768eb7703a
https://doi.org/10.1016/0040-4020(96)00579-0
https://doi.org/10.1016/0040-4020(96)00579-0
Publikováno v:
ChemInform. 27
Whereas thermal cyclisation of variously substituted 2,3-diarylacrylazides easily provided a new way to 3-aryl-isoquinolones, nitration of these compounds mainly led to corresponding 3-aryl-4-nitro-isoquinolones. After reduction into 4-amino-3-aryl-i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::80df98314632f51e458a9f536117357e
https://doi.org/10.1002/chin.199651128
https://doi.org/10.1002/chin.199651128
Autor:
Yasmina Saoudi, Corinne Guetta-Landras, Alexandra Erve, David S. Grierson, Andrei V. Popov, Sylvie Thirot, Chi-Hung Nguyen, Jean-Claude Florent
Publikováno v:
Nucleic Acids Research
Nucleic Acids Research, Oxford University Press, 2006, 34 (5), pp.e43. ⟨10.1093/nar/gkl011⟩
Nucleic Acids Research, 2006, 34 (5), pp.e43. ⟨10.1093/nar/gkl011⟩
Nucleic Acids Research, Oxford University Press, 2006, 34 (5), pp.e43. ⟨10.1093/nar/gkl011⟩
Nucleic Acids Research, 2006, 34 (5), pp.e43. ⟨10.1093/nar/gkl011⟩
International audience; N'-(2,8-Dimethoxy-12-methyl-dibenzo [c,h] [1,5] naphthyridin-6-yl)-N,N-dimethyl-propane-1,3-diamine (BENA435) is a new cell-membrane permeant DNA dye with absorption/emission maxima in complex with DNA at 435 and 484 nm. This
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f487230813c2d8e7fcf51dbe79b24248
https://www.hal.inserm.fr/inserm-00380059
https://www.hal.inserm.fr/inserm-00380059
Autor:
Stephane Leonce, Paola B. Arimondo, Claude Monneret, Dominique Guianvarc'h, Laurence Kraus-Berthier, Maria Duca, Alain Pierré, Daniel Dauzonne, Pierre Renard, Sylvie Thirot, Emmanuel Bertounesque, Philippe Meresse, Bruno Pfeiffer
Publikováno v:
Journal of medicinal chemistry. 48(2)
Etoposide (VP-16) is a potent human DNA topoisomerase II poison, derived from 4'-demethylepipodophyllotoxin, widely used in cancer chemotherapy. Continuous efforts have driven to synthesize new related compounds, presenting decreased toxic side effec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7c27b05e3824723b4dbfe2243948b49e
https://pubmed.ncbi.nlm.nih.gov/15658872
https://pubmed.ncbi.nlm.nih.gov/15658872
Publikováno v:
Bioorganic and Medicinal Chemistry
Bioorganic and Medicinal Chemistry, Elsevier, 2004, 12 (5), pp.969-977. ⟨10.1016/j.bmc.2003.12.013⟩
Bioorganic and Medicinal Chemistry, Elsevier, 2004, 12 (5), pp.969-977. ⟨10.1016/j.bmc.2003.12.013⟩
Described here are the syntheses and preliminary biological evaluations of the first two enzymatically activated prodrugs of docetaxel (Taxotere®) reported to date. These prodrugs were designed as potential candidates for selective chemotherapy in A
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e2218a6475a88fc8c6885fcab099aa0b
https://hal.archives-ouvertes.fr/hal-02137812
https://hal.archives-ouvertes.fr/hal-02137812
Autor:
Bruno Pfeiffer, Pierre Renard, Sylvie Thirot, Frédéric Schmidt, Stéphane Angenault, Claude Monneret
Publikováno v:
Bioorganic and Medicinal Chemistry Letters
Bioorganic and Medicinal Chemistry Letters, Elsevier, 2003, 13 (5), pp.947-950. ⟨10.1016/s0960-894x(02)01080-6⟩
Bioorganic and Medicinal Chemistry Letters, 2003, 13 (5), pp.947-950. ⟨10.1016/s0960-894x(02)01080-6⟩
Bioorganic and Medicinal Chemistry Letters, Elsevier, 2003, 13 (5), pp.947-950. ⟨10.1016/s0960-894x(02)01080-6⟩
Bioorganic and Medicinal Chemistry Letters, 2003, 13 (5), pp.947-950. ⟨10.1016/s0960-894x(02)01080-6⟩
A glucuronide-based prodrug of SN-38 (7-ethyl-10-hydroxycamptothecin) has been synthesized for use in a Prodrug MonoTherapy Strategy (PMT). Since this prodrug is significantly less cytotoxic than SN-38 itself and efficiently releases the drug in vitr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::db51f7cb9f76b06fdcfde315d962f5f3
https://hal.archives-ouvertes.fr/hal-02137820
https://hal.archives-ouvertes.fr/hal-02137820