The food-contaminant deoxynivalenol modifies eating by targeting anorexigenic neurocircuitry.

Autor: Clémence Girardet, Marion S Bonnet, Rajae Jdir, Medhi Sadoud, Sylvie Thirion, Catherine Tardivel, Julien Roux, Bruno Lebrun, Nicolas Wanaverbecq, Lourdes Mounien, Jérôme Trouslard, André Jean, Michel Dallaporta, Jean-Denis Troadec

Publikováno v: PLoS ONE, Vol 6, Iss 10, p e26134 (2011)

Physiological regulations of energy balance and body weight imply highly adaptive mechanisms which match caloric intake to caloric expenditure. In the central nervous system, the regulation of appetite relies on complex neurocircuitry which disturban

Externí odkaz: https://doaj.org/article/3a9e3ff99f5a494288ab718b91d7a4d9

Supplementary Figure 2 from Somatostatin Receptor sst2 Decreases Cell Viability and Hormonal Hypersecretion and Reverses Octreotide Resistance of Human Pituitary Adenomas

Autor: Anne Barlier, Alain Enjalbert, Thierry Brue, Henry Dufour, Dominique Figarella-Branger, Richard Cohen, Bettina Couderc, Anne Laure Germanetti, Ginette Gunz, Alexandru Saveanu, Catherine Roche, Sylvie Thirion, Julie Acunzo

Supplementary Figure 2 from Somatostatin Receptor sst2 Decreases Cell Viability and Hormonal Hypersecretion and Reverses Octreotide Resistance of Human Pituitary Adenomas

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2b84e33feabb334eb5309cfc62c43aaa
https://doi.org/10.1158/0008-5472.22376748.v1

Supplementary Figure 1 from Somatostatin Receptor sst2 Decreases Cell Viability and Hormonal Hypersecretion and Reverses Octreotide Resistance of Human Pituitary Adenomas

Autor: Anne Barlier, Alain Enjalbert, Thierry Brue, Henry Dufour, Dominique Figarella-Branger, Richard Cohen, Bettina Couderc, Anne Laure Germanetti, Ginette Gunz, Alexandru Saveanu, Catherine Roche, Sylvie Thirion, Julie Acunzo

Supplementary Figure 1 from Somatostatin Receptor sst2 Decreases Cell Viability and Hormonal Hypersecretion and Reverses Octreotide Resistance of Human Pituitary Adenomas

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::71365637198ee3726c9c68790e9c55fe
https://doi.org/10.1158/0008-5472.22376751.v1

Inactivation of PITX2 Transcription Factor Induced Apoptosis of Gonadotroph Tumoral Cells

Autor: Thierry Brue, Catherine Roche, Julie Acunzo, Céline Defilles, Anne Barlier, Isabelle Pellegrini, Alain Enjalbert, Thomas Graillon, Sylvie Thirion, Henry Dufour, Marie-Helene Quentien, Dominique Figarella-Branger

Publikováno v: Endocrinology
Endocrinology, Endocrine Society, 2011, 152 (10), pp.3884-92. ⟨10.1210/en.2011-1216⟩
Endocrinology, 2011, 152 (10), pp.3884-92. ⟨10.1210/en.2011-1216⟩

International audience; Nonfunctioning pituitary adenomas (NFPA; gonadotroph derived), even not inducing hormonal hypersecretion, cause significant morbidity by compression neighboring structures. No effective and specific medical methods are availab

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::64b239e62233dfa6587b3b9b0952fb0a
https://doi.org/10.1210/en.2011-1216

Somatostatin Receptor sst2 Decreases Cell Viability and Hormonal Hypersecretion and Reverses Octreotide Resistance of Human Pituitary Adenomas

Autor: Thierry Brue, Bettina Couderc, Richard B. Cohen, Alexandru Saveanu, Catherine Roche, Anne Laure Germanetti, Julie Acunzo, Ginette Gunz, Sylvie Thirion, Anne Barlier, Henry Dufour, Dominique Figarella-Branger, Alain Enjalbert

Publikováno v: Cancer Research. 68:10163-10170

In human somatotroph adenomas, growth hormone (GH) hypersecretion can be inhibited by somatostatin analogues such as octreotide. Unfortunately, serum GH levels reach normal values in only 60% of treated patients. The decreased sensitivity to octreoti

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0813680d90a51bd29c8a146deefb39da
https://doi.org/10.1158/0008-5472.can-08-1857