Zobrazeno 1 - 10
of 105
pro vyhledávání: '"Sylvie Rusakiewicz"'
Autor:
Devanjali Dutta, L. Francisco Lorenzo-Martín, François Rivest, Nicolas Broguiere, Lucie Tillard, Simone Ragusa, Nathalie Brandenberg, Sylke Höhnel, Damien Saugy, Sylvie Rusakiewicz, Krisztian Homicsko, George Coukos, Matthias P. Lutolf
Publikováno v:
npj Precision Oncology, Vol 8, Iss 1, Pp 1-7 (2024)
Abstract Immunotherapy has emerged as a new standard of care for certain cancer patients with specific cellular and molecular makeups. However, there is still an unmet need for ex vivo models able to readily assess the effectiveness of immunotherapeu
Externí odkaz:
https://doaj.org/article/500b8010d8694a5e80a921b03b5440e1
Autor:
Julien Schmidt, Johanna Chiffelle, Marta A. S. Perez, Morgane Magnin, Sara Bobisse, Marion Arnaud, Raphael Genolet, Julien Cesbron, David Barras, Blanca Navarro Rodrigo, Fabrizio Benedetti, Alexandra Michel, Lise Queiroz, Petra Baumgaertner, Philippe Guillaume, Michael Hebeisen, Olivier Michielin, Tu Nguyen-Ngoc, Florian Huber, Melita Irving, Stéphanie Tissot-Renaud, Brian J. Stevenson, Sylvie Rusakiewicz, Denarda Dangaj Laniti, Michal Bassani-Sternberg, Nathalie Rufer, David Gfeller, Lana E. Kandalaft, Daniel E. Speiser, Vincent Zoete, George Coukos, Alexandre Harari
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-15 (2023)
Abstract The success of cancer immunotherapy depends in part on the strength of antigen recognition by T cells. Here, we characterize the T cell receptor (TCR) functional (antigen sensitivity) and structural (monomeric pMHC-TCR off-rates) avidities o
Externí odkaz:
https://doaj.org/article/07eeb33e654749ddb84ed54edf7d260f
Autor:
Solange Peters, Urania Dafni, Panagiota Zygoura, Sanjay Popat, Mary O'Brien, Rolf A Stahel, Alessandra Curioni-Fontecedro, Georges Coukos, Amy Roy, Riyaz Shah, Krisztian Homicsko, James Spicer, Stephen P Finn, David Gilligan, Maxim Norkin, Stephanie Tissot, Nicholas Shakarishvili, Anthony Pope, Patricia Fisher, Sylvie Rusakiewicz, Ekaterina Fortis, Nesa Marti, Roswitha Kammler
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 11, Iss 10 (2023)
Background Few tissue biomarkers exist to date that could enrich patient with cancer populations to benefit from immune checkpoint blockade by programmed cell death protein 1/ligand-1 (PD-/L-1) inhibitors. PD-L1 expression has value in this context i
Externí odkaz:
https://doaj.org/article/6dd7fca327104b5ea4d8c47266ef755b
Autor:
George Coukos, Andrea Facciabene, Lana E Kandalaft, Christopher Neal, Dallas Flies, Justine Michaux, HuiSong Pak, Michal Bassani-Sternberg, Sarah F Adams, Sylvie Rusakiewicz, Georgia A McCann, Alizée J Grimm, Cheryl L-L Chiang, Ananda Mookerjee, Stephanie Jean, Florian Huber, Denarda Dangaj, Phyllis A Gimotty
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 8, Iss 2 (2020)
Background Novel therapeutic strategies in ovarian cancer (OC) are needed as the survival rate remains dismally low. Although dendritic cell-based cancer vaccines are effective in eliciting therapeutic responses, their complex and costly manufacturin
Externí odkaz:
https://doaj.org/article/d316f697081c43c3827481d33801e498
Autor:
Alexandre Ivagnès, Meriem Messaoudene, Gautier Stoll, Bertrand Routy, Aurélie Fluckiger, Takahiro Yamazaki, Kristina Iribarren, Connie P. M. Duong, Laetitia Fend, Anne Caignard, Isabelle Cremer, Axel LeCesne, Julien Adam, Charles Honoré, Olivier Mir, Loïc Chaigneau, Anne Berger, Pierre Validire, Christos Christidis, Valérie Le Brun-Ly, Mark J. Smyth, Xavier Mariette, Benoît L. Salomon, Guido Kroemer, Sylvie Rusakiewicz, Laurence Zitvogel
Publikováno v:
OncoImmunology, Vol 7, Iss 12 (2018)
Natural Killer (NK) cells control metastatic dissemination of murine tumors and are an important prognostic factor in several human malignancies. However, tumor cells hijack many of the NK cell functional features compromising their tumoricidal activ
Externí odkaz:
https://doaj.org/article/827dd603e2a54f17ad4e4777d94b2028
Autor:
Gaël Boivin, Pradeep Kalambaden, Julien Faget, Sylvie Rusakiewicz, Pierre Montay-Gruel, Etienne Meylan, Jean Bourhis, Guy Lesec, Marie-Catherine Vozenin
Publikováno v:
Frontiers in Oncology, Vol 8 (2018)
Immune-based anti-cancer strategies combined with radiation therapy (RT) are actively being investigated but many questions remain, such as the ideal treatment scheme and whether a potent immune response can be generated both locally and systemically
Externí odkaz:
https://doaj.org/article/3ec8f00a0d8d49ce8631cdd869cc95f2
Autor:
Nicolas Jacquelot, Jonathan M. Pitt, David P. Enot, Maria Paula Roberti, Connie P. M. Duong, Sylvie Rusakiewicz, Alexander M. Eggermont, Laurence Zitvogel
Publikováno v:
OncoImmunology, Vol 6, Iss 8 (2017)
Existing clinical, anatomopathological and molecular biomarkers fail to reliably predict the prognosis of cutaneous melanoma. Biomarkers for determining which patients receive adjuvant therapies are needed. The emergence of new technologies and the d
Externí odkaz:
https://doaj.org/article/c79e6bff49d74b6fbe3298685cce8dde
Autor:
Benjamin Besse, Mélinda Charrier, Valérie Lapierre, Eric Dansin, Olivier Lantz, David Planchard, Thierry Le Chevalier, Alain Livartoski, Fabrice Barlesi, Agnès Laplanche, Stéphanie Ploix, Nadège Vimond, Isabelle Peguillet, Clotilde Théry, Ludovic Lacroix, Inka Zoernig, Kavita Dhodapkar, Madhav Dhodapkar, Sophie Viaud, Jean-Charles Soria, Katrin S. Reiners, Elke Pogge von Strandmann, Frédéric Vély, Sylvie Rusakiewicz, Alexander Eggermont, Jonathan M. Pitt, Laurence Zitvogel, Nathalie Chaput
Publikováno v:
OncoImmunology, Vol 5, Iss 4 (2016)
Dendritic cell-derived exosomes (Dex) are small extracellular vesicles secreted by viable dendritic cells. In the two phase-I trials that we conducted using the first generation of Dex (IFN-γ-free) in end-stage cancer, we reported that Dex exerted n
Externí odkaz:
https://doaj.org/article/c7a0a68f62ab4eb68ba7db4a61d68e2f
Autor:
Anne I. Kraemer, Chloe Chong, Florian Huber, HuiSong Pak, Brian J. Stevenson, Markus Müller, Justine Michaux, Emma Ricart Altimiras, Sylvie Rusakiewicz, Laia Simó-Riudalbas, Evarist Planet, Maciej Wiznerowicz, Julien Dagher, Didier Trono, George Coukos, Stephanie Tissot, Michal Bassani-Sternberg
Publikováno v:
Nature cancer, vol. 4, no. 5, pp. 608-628
One key barrier to improving efficacy of personalized cancer immunotherapies that are dependent on the tumor antigenic landscape remains patient stratification. Although patients with CD3+CD8+ T cell-inflamed tumors typically show better response to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e7c7f7bff6f08a7d5efa2ad8565da395
https://doi.org/10.1038/s43018-023-00548-5
https://doi.org/10.1038/s43018-023-00548-5
Autor:
Anne Caignard, Marie-Françoise Avril, Antoine Toubert, Eric Pasmant, Ariel Savina, Fanny Bouquet, Houssem Benlalam, Brigitte Dréno, Florence Faure, Frédéric Vély, Eric Vivier, Laurence Zitvogel, Sylvie Rusakiewicz, Meriem Messaoudene, Emmanuelle Fourmentraux-Neves, Marina Colombo, Alexandra Frazao
List of antibodies used for flow cytometry.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a943f8011c94347f5285b8acb16e7518
https://doi.org/10.1158/2326-6066.22538722
https://doi.org/10.1158/2326-6066.22538722
