Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Sylvie Raher"'
Autor:
Isabelle Corre, Sylvie Hermouet, Eric Lippert, Anne Godard, Yannick Jacques, Sylvie Raher, Danielle Pineau
Publikováno v:
Cytokine. 20:178-183
We studied the production of interleukin (IL)-11 and IL-8, two cytokines known to affect erythropoiesis, in polycythemia vera (PV). In vivo, IL-11 was detected more frequently in serum and bone marrow (BM) plasma of PV patients than in controls (heal
Autor:
Olivier Boisteau, Yannick Jacques, Sylvie Raher, Jérôme Bernard, Sigrid Dubois, Sabine Leroy, Stephane Minvielle, Philippe Lehours, Anne Godard, Florence Magrangeas
Publikováno v:
Journal of Biological Chemistry. 274:26978-26984
We report the existence of eight different interleukin-15 receptor alpha-chain (IL-15Ralpha) transcripts resulting from exon-splicing mechanisms within the IL-15Ralpha gene. Two main classes of transcripts can be distinguished that do or do not (Delt
Autor:
Dominique Heymann, Yannick Jacques, Sylvie Raher, Frédéric Blanchard, Nadia Bentouimou, M M Hallet, Michel Chérel, Anne Godard
Publikováno v:
Cytokine. 8:197-205
The structure of Leukaemia Inhibitory Factor (LIF) and Oncostatin M (OSM) receptors is not completely resolved. Heterodimerization of gp190 and gp130 has been proposed to form a high af?nity receptor (type I) shared by LIF and OSM, while heterodimeri
Autor:
Jean Harb, Sylvie Raher, Frédéric Blanchard, Sophie Ringeard, Dominique Heymann, Anne Godard, Danielle Lassort
Publikováno v:
Cytokine. 7:111-117
ICAM-1-mediated cell-cell adhesion is essential for different immunologic functions including non-MHC-restricted cytotoxicity. The shedding of a soluble form off ICAM-1 from melanoma impairs immune recognition and leads to tumour escape. Pretreatment
Autor:
Frédéric Blanchard, Benjamin Chaigne-Delalande, Anne Godard, Patricia Vusio, Laurence Duplomb, Yannick Jacques, Sylvie Raher
Publikováno v:
Endocrinology. 144(12)
The calcium-independent mannose 6-phosphate receptor (CIMPR) is a receptor for multiple ligands, including leukemia inhibitory factor (LIF), an IL-6 type cytokine, and IGF-II. CIMPR targets newly synthesized ligands to lysosomes and induces internali
Publikováno v:
Cytokine. 12(5)
This study investigates the production of interleukin (IL-)1beta by cultured human bone marrow stromal cells. RT-PCR experiments indicate that two-thirds of cultures constitutively express IL-1beta mRNA transcripts. Their cell-associated IL-1beta lev
Autor:
Bernard Hoflack, Yannick Jacques, Sylvie Raher, Frédéric Blanchard, Anne Godard, Laurence Duplomb, Patricia Vusio
Publikováno v:
The Journal of biological chemistry. 274(35)
Leukemia inhibitory factor (LIF) is a multifunctional cytokine belonging to the interleukin-6 subfamily of helical cytokines, all of which use the glycoprotein (gp) 130 subunit for signal transduction. The specific receptor for LIF, gp190, binds this
Publikováno v:
Cytokine. 11(8)
Bone marrow stromal cells regulate marrow haematopoiesis by secreting interleukins (IL) such as IL-8. Lipid mediators modulate IL-8 synthesis in numerous cell types. We have investigated the effects of 5 lipid mediators (PAF, PGE(2), LTB(4), 12-HETE
Autor:
Vincent Pitard, Sophie Daburon, Anne Godard, Yannick Jacques, Sylvie Raher, Frédéric Blanchard, Jean-Luc Taupin, Jean-François Moreau, Véronique Miossec
Publikováno v:
The Journal of biological chemistry. 274(20)
The gp190 transmembrane protein, the low affinity receptor for the leukemia inhibitory factor (LIF), belongs to the hematopoietin family of receptors characterized by the cytokine binding domain (CBD). gp190 is one of the very few members of this fam
Autor:
Vincent Praloran, A Besse, Yves Denizot, R Nachat, Sylvie Raher, Franck Trimoreau, Anne Godard
Publikováno v:
Biochimica et biophysica acta. 1449(1)
Leukemia inhibitory factor (LIF), interleukin 6 (IL-6) and IL-8 are important regulators of inflammation and hematopoiesis. Human bone marrow stromal cells regulate marrow hematopoiesis by secreting cytokines. By using reverse-transcriptase polymeras