Zobrazeno 1 - 10
of 35
pro vyhledávání: '"Sylvie Pilote"'
Autor:
Benoit Drolet, Sylvie Pilote, Carolanne Gélinas, Alida-Douce Kamaliza, Audrey Blais-Boilard, Jessica Virgili, Dany Patoine, Chantale Simard
Publikováno v:
Pharmaceutics, Vol 9, Iss 4, p 44 (2017)
Arachidonic acid can be metabolized by cytochrome P450 (CYP450) enzymes in a tissue- and cell-specific manner to generate vasoactive products such as epoxyeicosatrienoic acids (EETs-cardioprotective) and hydroxyeicosatetraenoic acids (HETEs-cardiotox
Externí odkaz:
https://doaj.org/article/0168996e41bb44f294edfdb3e8525da2
Autor:
Mehdi El Hassani, Daniel J. G. Thirion, Kevin Koloskoff, Elias Matouk, Chantale Simard, Isabelle Cloutier, Sylvie Pilote, Amélie Marsot
Publikováno v:
Therapeutic Drug Monitoring. 45:259-264
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a6287aa3e0e4abff0703a0cbff4379e1
https://doi.org/10.1097/ftd.0000000000001053
https://doi.org/10.1097/ftd.0000000000001053
Autor:
Atziri Corin Chavez Alvarez, Chahrazed Bouzriba, Emmanuel Moreau, Philippe Auzeloux, Sophie Besse, Vincent Ouellette, Mitra Zarifi Khosroshahi, Marie-France Côté, Sylvie Pilote, Elisabeth Miot-Noirault, Jean-Michel Chezal, Chantale Simard, René C -Gaudreault, Sébastien Fortin
Publikováno v:
Journal of Medicinal Chemistry. 66:2477-2497
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7946defc659970b3f1ce92b47aaf85da
https://doi.org/10.1021/acs.jmedchem.2c01268
https://doi.org/10.1021/acs.jmedchem.2c01268
Publikováno v:
Journal of cardiovascular pharmacology. 80(4)
Bradycardia and QTc interval prolongation on the ECG have been reported with remdesivir (Veklury), an antiviral drug recently approved for treating severely ill patients with COVID-19. The objective was to evaluate the effects of remdesivir on cardia
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e5610304fd3739d849cb7df4ea274584
https://pubmed.ncbi.nlm.nih.gov/35881906
https://pubmed.ncbi.nlm.nih.gov/35881906
Autor:
Chantale Simard, Mehdi El Hassani, Amélie Marsot, Sylvie Pilote, Sara Soufsaf, Isabelle Cloutier
Publikováno v:
British journal of clinical pharmacologyREFERENCES. 88(5)
Aim Some population pharmacokinetic models have been developed using height to explain some of the interindividual variability in tobramycin pharmacokinetics in cystic fibrosis patients. However, their predictive performance when extrapolated to othe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b74ed04c23da33003c2842581f7211d3
https://pubmed.ncbi.nlm.nih.gov/34820875
https://pubmed.ncbi.nlm.nih.gov/34820875
Autor:
Chantale Simard, Sylvie Pilote, Benoit Drolet, Jean Champagne, Andrew D. Krahn, François Philippon, Zachary Laksman, Christian Steinberg
Publikováno v:
Experimental physiologyREFERENCES. 106(3)
NEW FINDINGS What is the role of SCN5A-C683R? SCN5A-C683R is a novel variant associated with an uncommon phenotype of adrenaline-triggered ventricular arrhythmia in the absence of a distinct ECG phenotype. What is the main finding and its importance?
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c6ff8c12d82dc0d74ec28fc4d42fc6c4
https://pubmed.ncbi.nlm.nih.gov/33480457
https://pubmed.ncbi.nlm.nih.gov/33480457
Autor:
Sébastien Fortin, Mathieu Gagné-Boulet, Chantale Simard, Atziri Corin Chavez Alvarez, Sylvie Pilote, René C.-Gaudreault, Chahrazed Bouzriba
Publikováno v:
Cancer Research. 81:1359-1359
Breast cancers (BC) are the most common cancers among women in North America. Several BC show high relapse rates or chemoresistance to current chemotherapies. Hence it is essential to develop new therapies to cure BC that would otherwise be lethal du
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9b54eb3ddd7f79cc1f2978d5c7d98d28
https://doi.org/10.1158/1538-7445.am2021-1359
https://doi.org/10.1158/1538-7445.am2021-1359
Publikováno v:
Fundamental & Clinical Pharmacology. 31:392-402
Cardiac arrhythmias and ECG abnormalities including bradycardia, prolongation of the QT interval, and atrioventricular (AV) conduction blocks have been extensively observed with fingolimod, the first marketed oral drug for treating the relapsing-remi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2112402bf537fc815ed46da00b45c13f
https://doi.org/10.1111/fcp.12284
https://doi.org/10.1111/fcp.12284
Publikováno v:
Biopharmaceutics & Drug Disposition. 36:183-203
Background: The guinea-pig is an excellent animal model for studying cardiopulmonary physiology/pharmacology. Interestingly, it also possesses a number of drug-metabolizing enzymes found in humans, such as CYP1A, CYP2D and CYP3A. Objective: To evalua
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::df5ae96852edcbd9584e1a4c9eab4d59
https://doi.org/10.1002/bdd.1931
https://doi.org/10.1002/bdd.1931
Autor:
Jessica Virgili, Dany Patoine, Audrey Blais-Boilard, Sylvie Pilote, Benoit Drolet, Chantale Simard, Carolanne Gélinas, Alida-Douce Kamaliza
Publikováno v:
Pharmaceutics
Pharmaceutics; Volume 9; Issue 4; Pages: 44
Pharmaceutics, Vol 9, Iss 4, p 44 (2017)
Pharmaceutics; Volume 9; Issue 4; Pages: 44
Pharmaceutics, Vol 9, Iss 4, p 44 (2017)
Arachidonic acid can be metabolized by cytochrome P450 (CYP450) enzymes in a tissue- and cell-specific manner to generate vasoactive products such as epoxyeicosatrienoic acids (EETs-cardioprotective) and hydroxyeicosatetraenoic acids (HETEs-cardiotox
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9f882e9b2290ef65d81d4c44bd9aab89
http://europepmc.org/articles/PMC5750650
http://europepmc.org/articles/PMC5750650