Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Sylvie LeGall"'
Autor:
Sylvie LeGall, Angela Meier, Judith Hellman, Mark A. Brockman, Galit Alter, Daniel G. Kavanagh, Hendrik Streeck, Todd J. Suscovich, Aranya Bagchi, Harlyn K. Sidhu, Marcus Altfeld
Publikováno v:
AIDS. 22:655-658
Increased PD-L1 expression has been reported in HIV-1-infected individuals, but the mechanisms leading to PD-L1 upregulation remain to be elucidated. Here we demonstrate that HIV-1-derived Toll-like receptor (TLR)7/8 ligands can induce MyD88-dependen
Autor:
Sylvie LeGall, Christian Brander, DB Weiner, Barbara K. Felber, Beatriz Mothe, A Valentin, Margherita Rosati, James I. Mullins, Matthieu Rolland, Viraj Kulkarni, G.N. Pavlakis, Niranjan Y. Sardesai
Publikováno v:
Retrovirology, Vol 9, Iss Suppl 2, p O67 (2012)
Retrovirology
Retrovirology
Background Immunodominance and sequence diversity are major hurdles in the development of effective HIV vaccines. We tested the hypothesis that a vaccine candidate composed of strictly Conserved Elements (CE) of the HIV proteome excluding the variabl
Publikováno v:
The Journal of Immunology. 194:149.8-149.8
Understanding the underlying immunological mechanisms of spontaneous HIV control by HIV+ elite controllers (EC) remains an important step in the development of efficient HIV vaccines and functional cures. To understand control mechanisms triggered by
Autor:
Sylvie LeGall, EH Doyle, RJ Lindsay, Julie Boucau, Marcus Altfeld, M Griesbeck, J. Judy Chang
Publikováno v:
Retrovirology
Retrovirology, Vol 9, Iss Suppl 2, p P176 (2012)
Retrovirology, Vol 9, Iss Suppl 2, p P176 (2012)
Background We previously showed that plasmacytoid dendritic cells (pDCs) derived from females can produce significantly more IFN-alpha in response to HIV-1 and HIV-1-encoded TLR7/8 ligands than pDCs derived from males, resulting in stronger secondary
Inherent baseline levels of phosphorylated IRF7 impact pDC IFNα response to TLR7 stimulation (108.8)
Autor:
Morgane Griesbeck, Erin Doyle, Robert Lindsay, Julie Boucau, Sylvie LeGall, Marcus Altfeld, J. Judy Chang
Publikováno v:
The Journal of Immunology. 188:108.8-108.8
Background: We previously showed that plasmacytoid dendritic cells (pDCs) derived from females can produce significantly more IFNα in response to HIV-1 and HIV-1-encoded TLR7/8 ligands than pDCs derived from males, resulting in stronger secondary ac