In VivoNMDA Receptor Activation Accelerates Motor Unit Maturation, Protects Spinal Motor Neurons, and Enhances SMN2 Gene Expression in Severe Spinal Muscular Atrophy Mice

Autor: Claude Pariset, Sylvie Lécolle, Olivier Biondi, Jocelyn Côté, Camille Lancelin, Gabriel Sanchez, Frédéric Charbonnier, Séverine Deforges, Philippe Lopes, Julien Branchu, Christophe Chanoine

Publikováno v: The Journal of Neuroscience. 30:11288-11299

Spinal muscular atrophy (SMA), a lethal neurodegenerative disease that occurs in childhood, is caused by the misexpression of the survival of motor neuron (SMN) protein in motor neurons. It is still unclear whether activating motor units in SMA corre

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::43c36626ad4a5c72c1c5ae745e4e12e8
https://doi.org/10.1523/jneurosci.1764-10.2010

Exercise-Induced Activation of NMDA Receptor Promotes Motor Unit Development and Survival in a Type 2 Spinal Muscular Atrophy Model Mouse

Autor: Hung Li, Philippe Lopes, Sylvie Lécolle, Séverine Deforges, Carmen Cifuentes-Diaz, Bruno Della Gaspera, Frédéric Charbonnier, Christophe Chanoine, Clément Grondard, Claude Pariset, Olivier Biondi

Publikováno v: Journal of Neuroscience
Journal of Neuroscience, Society for Neuroscience, 2008, 28 (4), pp.953-62. ⟨10.1523/JNEUROSCI.3237-07.2008⟩
Journal of Neuroscience, Society for Neuroscience, 2008, 28 (4), pp.953-62. <10.1523/JNEUROSCI.3237-07.2008>

Spinal muscular atrophy (SMA) is an inborn neuromuscular disorder caused by low levels of survival motor neuron protein, and for which no efficient therapy exists. Here, we show that the slower rate of postnatal motor-unit maturation observed in type

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1319a1cf6bbf0eca938087e589393c25
https://doi.org/10.1523/jneurosci.3237-07.2008

IGF-II is up-regulated and myofibres are hypertrophied in regenerating soleus of mice lacking FGF6

Autor: Anne-Sophie Armand, Bruno Della Gaspera, Thierry Launay, Christophe Chanoine, Daniel Birnbaum, Sylvie Lécolle, Claude Pariset, Frédéric Di Fiore, Frédéric Charbonnier

Publikováno v: Experimental Cell Research. 297:27-38

Important functions in myogenesis have been proposed for FGF6, a member of the fibroblast growth factor family accumulating almost exclusively in the myogenic lineage. However, the use of FGF6(-/-) mutant mice gave contradictory results and the role

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1313b20f4fcaf36fbe2c1a300a9f6a3b
https://doi.org/10.1016/j.yexcr.2004.02.021

A new role for the calcineurin/NFAT pathway in neonatal myosin heavy chain expression via the NFATc2/MyoD complex during mouse myogenesis

Autor: Suzie Lefebvre, Frédéric Charbonnier, Nissrine Daou, Christophe Chanoine, Sylvie Lécolle, Anne-Sophie Armand, Bruno Della Gaspera

Publikováno v: Development (Cambridge, England). 140(24)

The calcineurin/NFAT (nuclear factor of activated T-cells) signaling pathway is involved in the modulation of the adult muscle fiber type, but its role in the establishment of the muscle phenotype remains elusive. Here, we show that the NFAT member N

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3ee3eb55f7fc1e16d57d0773d776e079
https://pubmed.ncbi.nlm.nih.gov/24301466

Effects of inositol hexasulphate, a casein kinase inhibitor, on dentine phosphorylated proteins in organ culture of mouse tooth germs

Autor: Sylvie Lécolle, Maria Angelica Torres-Quintana, Michel Goldberg

Publikováno v: Archives of Oral Biology. 43:597-610

To study the effects of impaired protein phosphorylation on dentine formation and mineralization, inositol hexasulphate, an intracellular type I and type II casein kinase inhibitor, was used in an in vitro organotypic culture system. Mandibular first

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e2f096ce41816298cd0a6afcdac193e6
https://doi.org/10.1016/s0003-9969(98)00037-5