Zobrazeno 1 - 10
of 39
pro vyhledávání: '"Sylvie Jorieux"'
Autor:
Céline Borras, Kimberley Delaunay, Yousri Slaoui, Toufik Abache, Sylvie Jorieux, Marie-Christine Naud, Mohamed El Sanharawi, Emmanuelle Gelize, Patricia Lassiaz, Na An, Laura Kowalczuk, Cédric Ayassami, Alexandre Moulin, Francine Behar-Cohen, Frédéric Mascarelli, Virginie Dinet
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
A common allele (402H) of the complement factor H (FH) gene is the major risk factor for age-related macular degeneration (AMD), the leading cause of blindness in the elderly population. Development and progression of AMD involves vascular and inflam
Externí odkaz:
https://doaj.org/article/3646d397d2b940178ae9e6eb1094d66d
Autor:
Céline Monnet, Alexandre Fontayne, Benjamin Beaufils, Emilie Jacque, Anais Engrand, Lennart T. Mars, Aurélie Dehenne, Christophe De Romeuf, Nathalie Fournier, Aurélie Terrier, Anne-Sophie Dezetter, Philippe Mondon, Mathilde Bas, Virginie Pochet-Beghin, Sylvie Jorieux, Cécile Beghin, Gilles Dupont
Publikováno v:
The Journal of Immunology. 202:1582-1594
The long serum t1/2 of IgGs is ensured by their interaction with the neonatal Fc receptor (FcRn), which salvages IgG from intracellular degradation. Fc glycosylation is thought not to influence FcRn binding and IgG longevity in vivo. In this article,
Autor:
Olivier Levy, Sophie Lavalette, Przemyslaw Sapieha, Xavier Guillonneau, Matthew C. Pickering, William Raoul, Shulong J. Hu, Emmanuel L. Gautier, Lucie Poupel, Philippe Karoyan, Julie Rayes, Alexandre Fauvet, José-Alain Sahel, Thomas Denèfle, Fanny Beguier, J.-B. Conart, Claire L. Harris, Patrick Sullivan, Bertrand Calippe, Catherine Fitting, Sébastien Augustin, Florian Sennlaub, Sylvie Jorieux, Hugo Charles-Messance
Publikováno v:
Immunity
Immunity, 2017, 46 (2), pp.261-272. ⟨10.1016/j.immuni.2017.01.006⟩
Immunity, Elsevier, 2017, 46 (2), pp.261-272. 〈10.1016/j.immuni.2017.01.006〉
Immunity, Elsevier, 2017, 46 (2), pp.261-272. ⟨10.1016/j.immuni.2017.01.006⟩
Immunity, 2017, 46 (2), pp.261-272. ⟨10.1016/j.immuni.2017.01.006⟩
Immunity, Elsevier, 2017, 46 (2), pp.261-272. 〈10.1016/j.immuni.2017.01.006〉
Immunity, Elsevier, 2017, 46 (2), pp.261-272. ⟨10.1016/j.immuni.2017.01.006⟩
International audience; Variants of the CFH gene, encoding complement factor H (CFH), show strong association with age-related macular degeneration (AMD), a major cause of blindness. Here, we used murine models of AMD to examine the contribution of C
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ccfa4e1d9e48f1ff053d36dc4083e34b
https://www.hal.inserm.fr/inserm-01755551
https://www.hal.inserm.fr/inserm-01755551
Autor:
Nathalie Souyris, Fabien Crozet, Christian Behrens, Céline Monnet, Alexandra Jacquet, Sylvie Jorieux, Ouafa Zaki, Khalil Bouayadi, Alexandre Fontayne, Nathalie Fournier, Rémi Urbain, Christophe De Romeuf, Philippe Mondon
Publikováno v:
mAbs. 6:422-436
While glyco-engineered monoclonal antibodies (mAbs) with improved antibody-dependent cell-mediated cytotoxicity (ADCC) are reaching the market, extensive efforts have also been made to improve their pharmacokinetic properties to generate biologically
Publikováno v:
Biologicals : journal of the International Association of Biological Standardization. 44(4)
Albumin displays several important functions for homeostasis amongst which the maintenance of the plasma redox-state. The study aim was to compare the redox state of pharmaceutical human albumin preparations since it reflects the oxidation-reduction
Autor:
Arnaud Glacet, Vincent Vieillard, Christine Gaucher, Charles-Antoine Dutertre, Dominique Bourel, J F Prost, Sylvie Jorieux, Magali Le Garff-Tavernier, Hélène Merle-Béral, Nathalie Fournier, Nicolas Bihoreau, Jean-Luc Teillaud, Christian Behrens, Christophe De Romeuf, Bruno Cazin, Roland Beliard
Publikováno v:
British Journal of Haematology. 140:635-643
Patients with chronic lymphocytic leukaemia (CLL) treated with a combination of fludarabine, cyclophosphamide and rituximab show a high response rate. However, only a poor response is observed following rituximab monotherapy. The use of chemo-immunot
Autor:
Philippe Mondon, Nathalie Fournier, Christian Behrens, Sylvie Jorieux, Christophe De Romeuf, Rã©Mi Urbain, Alexandre Fontayne, Khalil Bouayadi, Cã©Line Monnet
Publikováno v:
Frontiers in Immunology
Frontiers in Immunology, Vol 6 (2015)
Frontiers in Immunology, Vol 6 (2015)
Despite the reasonably long half-life of immunoglogulin G (IgGs), market pressure for higher patient convenience while conserving efficacy continues to drive IgG half-life improvement. IgG half-life is dependent on the neonatal Fc receptor (FcRn), wh
Autor:
Renée Ménez, Enrico A. Stura, Jean-Luc Teillaud, Sophie Sibéril, Charlotte Boix, Wolf H. Fridman, Charles-Antoine Dutertre, Emmanuelle Bonnin, Sylvie Jorieux
Publikováno v:
Immunology Letters. 106:111-118
The binding of IgG antibodies to receptors for the Fc region of IgG (FcgammaR) is a critical step for the initiation and/or the control of effector immune functions once immune complexes have been formed. Site-directed and random mutagenesis as well
Autor:
Edith Fressinaud, M. Guicheteau, Claudine Mazurier, M. Fontenay-Roupie, Dominique Meyer, Lysiane Hilbert, Sylvie Jorieux
Publikováno v:
British Journal of Haematology. 127:184-189
Type 2N von Willebrand disease (VWD) is characterized by a markedly decreased affinity of von Willebrand factor (VWF) for factor VIII (FVIII). The FVIII binding site has been localized within the first 272 amino acid residues of mature VWF, encoded b
Autor:
Claudine Mazurier, Dominique Meyer, Valérie Proulle, Armelle Parquet, Lysiane Hilbert, Jenny Goudemand, Rémi Favier, Sylvie Jorieux, Edith Fressinaud
Publikováno v:
British Journal of Haematology. 120:627-632
In type 2N von Willebrand disease (VWD), von Willebrand factor (VWF) is characterized by a markedly decreased affinity for Factor VIII (FVIII), and the mutations responsible are essentially located in the D' domain of VWF. We report the identificatio