Zobrazeno 1 - 10
of 37
pro vyhledávání: '"Sylvie Guerder"'
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
Dendritic cells (DCs) form a collection of antigen-presenting cells (APCs) that are distributed throughout the body. Conventional DCs (cDCs), which include the cDC1 and cDC2 subsets, and plasmacytoid DCs (pDCs) constitute the two major ontogenically
Externí odkaz:
https://doaj.org/article/f17a0ebac99644a8b1e0ffad71c8f8ca
Autor:
Corinne Aubel, Frédérique Penault-Lorca, F. Magnier, Clémence Dubois, Emmanuelle Mounetou, Mahchid Bamdad, Fanny Martin, Pierre Daumar, Chervin Hassel, Sylvie Guerder
Publikováno v:
Journal of Clinical Medicine, Vol 9, Iss 1, p 64 (2019)
Journal of Clinical Medicine
Journal of Clinical Medicine, MDPI, 2019, 9 (1), pp.64. ⟨10.3390/jcm9010064⟩
Journal of Clinical Medicine, 2019, 9 (1), pp.64. ⟨10.3390/jcm9010064⟩
Volume 9
Issue 1
Journal of Clinical Medicine
Journal of Clinical Medicine, MDPI, 2019, 9 (1), pp.64. ⟨10.3390/jcm9010064⟩
Journal of Clinical Medicine, 2019, 9 (1), pp.64. ⟨10.3390/jcm9010064⟩
Volume 9
Issue 1
The Triple-Negative Breast Cancer subtype (TNBC) is particularly aggressive and heterogeneous. Thus, Poly-ADP-Ribose Polymerase inhibitors were developed to improve the prognosis of patients and treatment protocols are still being evaluated. In this
Publikováno v:
Immunogenetics
Immunogenetics, 2019, 71 (3), pp.223-232. ⟨10.1007/s00251-018-1078-y⟩
Immunogenetics, Springer Verlag, 2019, 71 (3), pp.223-232. ⟨10.1007/s00251-018-1078-y⟩
Immunogenetics, 2019, 71 (3), pp.223-232. ⟨10.1007/s00251-018-1078-y⟩
Immunogenetics, Springer Verlag, 2019, 71 (3), pp.223-232. ⟨10.1007/s00251-018-1078-y⟩
International audience; The lifespan of T cells is determined by continuous interactions of their T cell receptors (TCR) with self-peptide-MHC (self-pMHC) complexes presented by different subsets of antigen-presenting cells (APC). In the thymus, deve
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0acc50af89ab11461537b79f18501d6d
https://www.hal.inserm.fr/inserm-02410117
https://www.hal.inserm.fr/inserm-02410117
Publikováno v:
European Journal of Immunology. 46:609-618
The elimination of solid tumors largely depends on effective T-cell priming by dendritic cells (DCs). For decades, studies focusing on antitumoral immune responses have been performed with tumors transplanted subcutaneously (s.c.). These studies howe
Publikováno v:
The Journal of Immunology. 195:1964-1973
Multiple studies highlighted the overtly self-reactive T cell repertoire in the diabetes-prone NOD mouse. This autoreactivity has primarily been linked to defects in apoptosis induction during central tolerance. Previous studies suggested that thymus
Publikováno v:
European Journal of Immunology. 45:1946-1956
Although central tolerance induces the deletion of most autoreactive T cells, some autoreactive T cells escape thymic censorship. Whether potentially harmful autoreactive T cells present distinct TCRαβ features remains unclear. Here, we analyzed th
Autor:
Sylvie Guerder, Abdoulraouf Ramadan, Lennart T. Mars, Paul Menut, Karim Mahiddine, Laurent Serre, Maeva Girard, Nelly Rouquié, Bertrand Leobon, Liliana E. Lucca
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 199(11)
The genetic predisposition to multiple sclerosis (MS) is most strongly conveyed by MHC class II haplotypes, possibly by shaping the autoimmune CD4 T cell repertoire. Whether Ag-processing enzymes contribute to MS susceptibility by editing the peptide
Publikováno v:
Journal of Immunological Methods. 384:103-110
Mice with virtually all T cells expressing a single T cell receptor (TCR) on their surface have been instrumental in understanding the development of immature thymocytes. For many years, such an engineering has been achieved essentially by inserting
Publikováno v:
médecine/sciences. 24:972-976
After more than 20 years of hegemony, the Th1-Th2 paradigm was recently shaken by the discovery of a novel population of CD4 effector T cells, the Th17 cells. Th17 effector cells produce IL-17 and IL-22 and thus have pro-inflammatory properties notab
Autor:
F. Susan Wong, Sylvie Guerder, Ian J. Thomas, David C. Wraith, Richard M. Smith, Richard A. Flavell, Liliana G. Petrich de Marquesini, Li Wen, Rommel Ravanan
Publikováno v:
The Journal of Immunology. 179:5936-5946
CD80 and CD86 both costimulate T cell activation. Their individual effects in vivo are difficult to study as they are coordinately up-regulated on APCs. We have studied mice expressing rat insulin promoter (RIP)-CD80 and RIP-CD86 on the NOD and NOD.s