Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Sylvie Gontier"'
Autor:
Kirsten Bjergarde, Cécile Delorme, Pierre-Yves Abecassis, Alain Krick, Jean-Paul Nicolas, Gilles Doerflinger, Sébastien Perron, Michel Murer, Houlfa Guizani, Bruno Filoche-Romme, Sylvette Lachaud, Ronan Le Moigne, Céline Prévost, Cécile Combeau, Jacques Mauger, Jean-Christophe Carry, Stéphanie Pouzieux, Laure Delarbre, Laurent Schio, Francois Clerc, Marie-Line Monteiro, Hervé Minoux, Sylvie Monget, Thomas Bertrand, Véronique Crocq-Stuerga, Ma Nina, Francis Gasse, Odile Angouillant-Boniface, Rémi Lebel, Sébastien Maignan, Sylvie Gontier, Anil Nair, Eric Parmantier
Publikováno v:
Journal of medicinal chemistry. 58(1)
The Aurora family of serine/threonine kinases is essential for mitosis. Their crucial role in cell cycle regulation and aberrant expression in a broad range of malignancies have been demonstrated and have prompted intensive search for small molecule
Autor:
Patrick Jimonet, François Audiau, Michel Barreau, Jean-Charles Blanchard, Alain Boireau, Yvette Bour, Marie-Annick Coléno, Adam Doble, Gilles Doerflinger, Claudine Do Huu, Marie-Hélène Donat, Jean Marie Duchesne, Pierre Ganil, Claude Guérémy, Eliane Honoré, Bernard Just, Roselyne Kerphirique, Sylvie Gontier, Philippe Hubert, Pierre M. Laduron, Joseph Le Blevec, Mireille Meunier, Jean-Marie Miquet, Conception Nemecek, Martine Pasquet, Odile Piot, Jeremy Pratt, Jean Rataud, Michel Reibaud, Jean-Marie Stutzmann, Serge Mignani
Publikováno v:
Journal of medicinal chemistry. 42(15)
Two series of analogues of riluzole, a blocker of excitatory amino acid mediated neurotransmission, have been synthesized: monosubstituted 2-benzothiazolamines and 3-substituted derivatives. Of all the compounds prepared in the first series, only 2-b