Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Sylvie Dutka-Malen"'
Autor:
Marc Galimand, Stefan Evers, Barbara Casadewall, Murielle Charles, Patrice Courvalin, Sylvie Dutka-Malen
Publikováno v:
Journal of Molecular Evolution. 42:706-712
The D-alanine:D-alanine-ligase-related enzymes can have three preferential substrate specificities. Usually, these enzymes synthesize D-alanyl-D-alanine. In vancomycin-resistant Gram-positive bacteria, structurally related enzymes synthesize D-alanyl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6dcfc9b455095133c9d64fb285935ca9
https://doi.org/10.1007/bf02338803
https://doi.org/10.1007/bf02338803
Autor:
Sylvie Dutka-Malen, Michel Tabart, Guy Picaut, Yvette Huet, Jean-Francois Desconclois, Nadine Berthaud
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 11:919-921
We describe here the synthesis and biological evaluation of a series of benzo[b]naphthyridones, a new family of tricyclic antibacterial compounds that have a gram-positive spectrum of activity. RP60556A, one of the most potent of these compounds, is
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9f585fd1ab91d9fea477eed18699b2e2
https://doi.org/10.1016/s0960-894x(01)00091-9
https://doi.org/10.1016/s0960-894x(01)00091-9
Autor:
Nadine Berthaud, Jean-Francois Desconclois, Guy Picaut, Michel Tabart, Sylvie Dutka-Malen, Yvette Huet
Publikováno v:
ChemInform. 32
We describe here the synthesis and biological evaluation of a series of benzo[b]naphthyridones, a new family of tricyclic antibacterial compounds that have a Gram-positive spectrum of activity. RP60556A, one of the most potent of these compounds, is
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::aaca255eb8f7e75a53ae69d8413dc48f
https://doi.org/10.1002/chin.200150148
https://doi.org/10.1002/chin.200150148
Publikováno v:
Antimicrobial Agents and Chemotherapy. 36:2005-2008
Nearly all strains of Enterococcus gallinarum are resistant to low levels of vancomycin. The glycopeptide resistance gene vanC from E. gallinarum BM4174 has recently been cloned and sequenced. A probe specific for vanC hybridized with a 2.7-kb EcoRI
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a53fa14539f1d5982a0cd81c14e29232
https://doi.org/10.1128/aac.36.9.2005
https://doi.org/10.1128/aac.36.9.2005
Autor:
Patrice Courvalin, Sylvie Dutka-Malen, Timothy D. H. Bugg, Christopher T. Walsh, Michel Arthur
Publikováno v:
Biochemistry. 30:2017-2021
High-level glycopeptide resistance in Enterococcus faecium BM4147 is mediated by a 38-kDa protein VanA, whose amino acid sequence is related to Gram-negative D-alanine:D-alanine (D-Ala-D-Ala) ligases [Dutka-Malen, S., Molinas, C., Arthur, M., & Courv
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a8dd6acbcfbd972c2a26efbc39528e10
https://doi.org/10.1021/bi00222a002
https://doi.org/10.1021/bi00222a002
Autor:
Patrice Courvalin, Sylvie Dutka-Malen
Publikováno v:
Antimicrobic Newsletter. 7:81-86
The glycopeptides vancomycin and teicoplanin constitute an important class of antibiotics for the treatment of severe infections due to Gram-positive bacteria, including staphylococci, enterococci, and streptococci. These antibiotics inhibit late sta
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ea6a3184db3fe05c115e6289f15acb73
https://doi.org/10.1016/0738-1751(90)90027-a
https://doi.org/10.1016/0738-1751(90)90027-a
Autor:
Sylvie Wentzler, Lavergne Marc Pierre, Nadine Berthaud, Sylvie Dutka-Malen, Jean-Luc Malleron, Guy Picaut, Michel Tabart
Publikováno v:
Bioorganicmedicinal chemistry letters. 13(7)
The synthesis and antibacterial activity of benzo[f][1,7]naphtyridone derivatives are reported. These compounds are potent antibacterial agents with a Gram-positive spectrum of activity. They are active against multi-resistant cocci, especially Staph
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::531e64f190a38fcac51f38ac60413292
https://pubmed.ncbi.nlm.nih.gov/12657275
https://pubmed.ncbi.nlm.nih.gov/12657275
Autor:
Annie Canu, Bülent Bozdogan, Celine Feger, Roland Leclercq, Virginie Zarrouk, Bruno Fantin, Sylvie Dutka-Malen, Brigitte Malbruny
Publikováno v:
Antimicrobial agents and chemotherapy. 46(7)
The mechanism of resistance to the streptogramin antibiotics quinupristin and dalfopristin was studied in aStaphylococcus aureusclinical isolate selected under quinupristin-dalfopristin therapy, in four derivatives ofS. aureusRN4220 selected in vitro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bb8dbce442051243986e195f939bfba0
https://pubmed.ncbi.nlm.nih.gov/12069975
https://pubmed.ncbi.nlm.nih.gov/12069975
Autor:
Patrice Courvalin, S. Evers, Richard Quintiliani, Sylvie Dutka-Malen, Florence Depardieu, Peter E. Reynolds, Michel Arthur
Publikováno v:
The Journal of infection. 32(1)
Inducible resistance to high levels of glycopeptide antibiotics in clinical isolates of enterococci is mediated by Tn1546 or related transposons. Tn1546 encodes the VanH dehydrogenase which reduces pyruvate to D-lactate (D-Lac) and the VanA ligase wh
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c887ddb512d9c91466bf7c3bf18af12c
https://pubmed.ncbi.nlm.nih.gov/8852545
https://pubmed.ncbi.nlm.nih.gov/8852545
Publikováno v:
Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases. 1(1)
Twenty-four clinical isolates of Staphylococcus aureus collected from various geographic areas and four reference strains were studied by (i) agar diffusion with disks impregnated with 5 microg oxacillin and reading after incubation at 30C for 24 hou
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::10feafe3b597bc47ff172c5c914ef98c
https://pubmed.ncbi.nlm.nih.gov/11866722
https://pubmed.ncbi.nlm.nih.gov/11866722