Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Sylvie Délos"'
Publikováno v:
International Journal of Cancer. 75:840-846
The aim of this study on testosterone (T) metabolism in benign prostatic hyperplasia (BPH) and prostatic cancer was to compare the formation of metabolites in freshly isolated epithelial cells and in cells of long-term cultures (2 passages) and to id
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bdbd95dca4f4492840004c09b37b0b01
https://doi.org/10.1002/(sici)1097-0215(19980316)75:6<840::aid-ijc5>3.0.co
https://doi.org/10.1002/(sici)1097-0215(19980316)75:6<840::aid-ijc5>3.0.co
Publikováno v:
The Journal of Steroid Biochemistry and Molecular Biology. 55:375-383
We compare testosterone (T) metabolism in primary cultures of epithelial cells and fibroblasts separated from benign prostate hypertrophy (BPH) and prostate cancer tissues. In all cultures, androstenedione (delta 4) formed by oxidation of T by 17 bet
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8bfb8cf86d7db56c65f77efca2277e98
https://doi.org/10.1016/0960-0760(95)00184-0
https://doi.org/10.1016/0960-0760(95)00184-0
Autor:
Rothwell Tate, O. Guirou, Jean-Pierre Raynaud, Sylvie Délos, Pierre-Marie Martin, Catherine Iehlé
Publikováno v:
The Journal of Steroid Biochemistry and Molecular Biology. 54:273-279
The present study describes the independent expression of the type 1 and 2 isoforms of human 5 alpha-reductase in the baculovirus-directed insect cell expression system and the selectivity of their inhibition. The catalytic properties and kinetic par
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::44b72e6ae9d335a1905903d53ef89e1e
https://doi.org/10.1016/0960-0760(95)00134-l
https://doi.org/10.1016/0960-0760(95)00134-l
Publikováno v:
The Journal of Steroid Biochemistry and Molecular Biology. 46:177-182
In the human prostate, the enzyme steroid 5 alpha-reductase (h5 alpha R) catalyses the conversion of testosterone into the more potent androgen, dihydrotestosterone. Two distinct cDNAs coding for h 5 alpha R in the human prostate have been previously
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d677aafc8414a04bc0ad5e28126843d9
https://doi.org/10.1016/0960-0760(93)90292-5
https://doi.org/10.1016/0960-0760(93)90292-5
Publikováno v:
The Journal of steroid biochemistry and molecular biology. 48(4)
The purpose of this study was 2-fold: (1) to identify the 5 alpha-reductase (5 alpha-R) isozyme(s) present in DU 145 cells, a human cell-line of low androgen sensitivity derived from a cerebral metastasis of an epithelial prostate cancer; and (2) to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::90cb657d7235cc3abd4822197893b233
https://pubmed.ncbi.nlm.nih.gov/8142312
https://pubmed.ncbi.nlm.nih.gov/8142312
Publikováno v:
Pharmacological Research. 31:31
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bf9be622d7069812162ab930865ded1f
https://doi.org/10.1016/1043-6618(95)86383-4
https://doi.org/10.1016/1043-6618(95)86383-4