Zobrazeno 1 - 10 of 34 pro vyhledávání: '"Sylvie Coscoy"'
1
Akademický článek
A role for Dynlt3 in melanosome movement, distribution, acidity and transfer
Autor: Zackie Aktary, Alejandro Conde-Perez, Florian Rambow, Mathilde Di Marco, François Amblard, Ilse Hurbain, Graça Raposo, Cédric Delevoye, Sylvie Coscoy, Lionel Larue
Publikováno v: Communications Biology, Vol 4, Iss 1, Pp 1-15 (2021)
Aktary et al. identify novel roles for the dynein light chain Dynlt3 in melanosome transport, maturation, and transfer to keratinocytes. They also find that the Wnt/βcatenin signalling pathway controls Dynlt3 levels and thus also contributes to the
Externí odkaz: https://doaj.org/article/63bc3c1ea59f4abfb5884cb3200a500b
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2
Akademický článek
A Multitubular Kidney-on-Chip to Decipher Pathophysiological Mechanisms in Renal Cystic Diseases
Autor: Sarah Myram, Bastien Venzac, Brice Lapin, Aude Battistella, Fanny Cayrac, Bertrand Cinquin, Charles Cavaniol, Giacomo Gropplero, Isabelle Bonnet, Sophie Demolombe, Stéphanie Descroix, Sylvie Coscoy
Publikováno v: Frontiers in Bioengineering and Biotechnology, Vol 9 (2021)
Autosomal Dominant Polycystic Kidney Disease (ADPKD) is a major renal pathology provoked by the deletion of PKD1 or PKD2 genes leading to local renal tubule dilation followed by the formation of numerous cysts, ending up with renal failure in adultho
Externí odkaz: https://doaj.org/article/228122e82c43454b8846384e590894c0
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3
Akademický článek
Dynamics of Endothelial Engagement and Filopodia Formation in Complex 3D Microscaffolds
Autor: Pierre Ucla, Xingming Ju, Melisa Demircioglu, Sarah Baiz, Laurent Muller, Stéphane Germain, Catherine Monnot, Vincent Semetey, Sylvie Coscoy
Publikováno v: International Journal of Molecular Sciences, Vol 23, Iss 5, p 2415 (2022)
The understanding of endothelium–extracellular matrix interactions during the initiation of new blood vessels is of great medical importance; however, the mechanobiological principles governing endothelial protrusive behaviours in 3D microtopograph
Externí odkaz: https://doaj.org/article/0eb9fdc793db467b867fde738cbc49c2
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4
Akademický článek
Loss of the Metastasis Suppressor NME1, But Not of Its Highly Related Isoform NME2, Induces a Hybrid Epithelial–Mesenchymal State in Cancer Cells
Autor: Anda Huna, Béatrice Nawrocki-Raby, Teresita Padilla-Benavides, Julie Gavard, Sylvie Coscoy, David Bernard, Mathieu Boissan
Publikováno v: International Journal of Molecular Sciences, Vol 22, Iss 7, p 3718 (2021)
Epithelial–mesenchymal transition (EMT) is important for the initial steps of metastasis. Although it is well accepted that the nucleoside diphosphate kinase NME1 is a metastasis suppressor, its effect on EMT remains poorly documented, as does that
Externí odkaz: https://doaj.org/article/71f2557a87d540809c573373e5ef3e62
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5
Akademický článek
Mechanosensitive Adaptation of E-Cadherin Turnover across adherens Junctions.
Autor: Simon de Beco, Jean-Baptiste Perney, Sylvie Coscoy, François Amblard
Publikováno v: PLoS ONE, Vol 10, Iss 6, p e0128281 (2015)
In the natural and technological world, multi-agent systems strongly depend on how the interactions are ruled between their individual components, and the proper control of time-scales and synchronization is a key issue. This certainly applies to liv
Externí odkaz: https://doaj.org/article/3760dbf1cb3646c4b3b910d147bebab9
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7
A role for Dynlt3 in melanosome movement, distribution, acidity and transfer
Autor: Alejandro Conde-Perez, Mathilde Di Marco, Sylvie Coscoy, Cédric Delevoye, Florian Rambow, Lionel Larue, Graça Raposo, Zackie Aktary, François Amblard, Ilse Hurbain
Publikováno v: Communications Biology, Vol 4, Iss 1, Pp 1-15 (2021)
Communications Biology
Communications Biology, 2021, 4 (1), pp.423. ⟨10.1038/s42003-021-01917-5⟩
Communications Biology, Nature Publishing Group, 2021, 4 (1), pp.423. ⟨10.1038/s42003-021-01917-5⟩
Skin pigmentation is dependent on cellular processes including melanosome biogenesis, transport, maturation and transfer to keratinocytes. However, how the cells finely control these processes in space and time to ensure proper pigmentation remains u
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6128aaffe8f0da93543fcdc7d845c617
https://doaj.org/article/63bc3c1ea59f4abfb5884cb3200a500b
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8
Mutations in calmodulin-binding domains of TRPV4/6 channels confer invasive properties to colon adenocarcinoma cells
Autor: Atousa Arbabian, Param Priya Singh, Mircea Iftinca, Hervé Isambert, Christophe Altier, Sylvie Coscoy
Publikováno v: Channels
Channels, Taylor & Francis, 2020, 14 (1), pp.101-109. ⟨10.1080/19336950.2020.1740506⟩
International audience; Transient receptor potential (TRP) channels form a family of polymodal cation channels gated by thermal, mechanical, or chemical stimuli, with many of them involved in the control of proliferation, apoptosis, or cell cycle. Fr
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::44d110e7feca2a3f330fbf52f4bfd456
https://doi.org/10.1080/19336950.2020.1740506
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9
Dynamics of Endothelial Engagement and Filopodia Formation in Complex 3D Microscaffolds
Autor: Pierre Ucla, Xingming Ju, Melisa Demircioglu, Sarah Baiz, Laurent Muller, Stéphane Germain, Catherine Monnot, Vincent Semetey, Sylvie Coscoy
Publikováno v: International Journal of Molecular Sciences
International Journal of Molecular Sciences, 2022, 23 (5), ⟨10.3390/ijms23052415⟩
International Journal of Molecular Sciences; Volume 23; Issue 5; Pages: 2415
The understanding of endothelium–extracellular matrix interactions during the initiation of new blood vessels is of great medical importance; however, the mechanobiological principles governing endothelial protrusive behaviours in 3D microtopograph
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e13546506d1db612b94704236ef3919d
https://pubmed.ncbi.nlm.nih.gov/35269558
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10
Loss of the Metastasis Suppressor NME1, But Not of Its Highly Related Isoform NME2, Induces a Hybrid Epithelial–Mesenchymal State in Cancer Cells
Autor: David Bernard, Sylvie Coscoy, Teresita Padilla-Benavides, Anda Huna, Julie Gavard, B. Nawrocki-Raby, Mathieu Boissan
Publikováno v: International Journal of Molecular Sciences
International Journal of Molecular Sciences, MDPI, 2021, 22 (7), pp.3718. ⟨10.3390/ijms22073718⟩
International Journal of Molecular Sciences, 2021, 22 (7), pp.3718. ⟨10.3390/ijms22073718⟩
International Journal of Molecular Sciences, Vol 22, Iss 3718, p 3718 (2021)
Volume 22
Issue 7
International audience; Epithelial–mesenchymal transition (EMT) is important for the initial steps of metastasis. Although it is well accepted that the nucleoside diphosphate kinase NME1 is a metastasis suppressor, its effect on EMT remains poorly
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c62b0a04657086a04449d7c5920bceeb
https://www.hal.inserm.fr/inserm-03191241
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